Ngabe i-Biologics Inketho Yokwelapha I-PsA?

-Delile

• Ngabe i-biologics isetshenziswa nini?
• Ngubani ofanelekela i-biologics?
• Indawo ye-Psoriasis Area and Severity Index (PASI)
• I-Dermatology Quality of Life Index (DQLI)
• I-Peripheral psoriatic arthritis
• I-axial psoriatic arthritis
• Ubani ongafaneleki ku-biologics?
• Ukuthatha

Ukubuka konke

I-Psoriatic arthritis (i-PsA) uhlobo lwe-arthritis oluthinta abanye abantu abane-psoriasis. Kuyindlela engapheli, evuthayo yesifo samathambo eqala emajoyintini amakhulu.

Esikhathini esedlule, i-PsA ibiphathwa ngokuyinhloko ngemithi yokujova neyomlomo kadokotela. Noma kunjalo, le mithi ayisebenzi ngaso sonke isikhathi. Zingadala nemiphumela engemihle. Ngenxa yalokhu, isizukulwane esisha semithi esibizwa nge-biologics sisetshenziselwa ukwelapha iPSA emaphakathi kuya kwelenzima.

Ama-biologics anamandla, izidakamizwa eziqondene ngqo. Benza ngokuvimba izindlela ezithile zokuvuvukala ezidlala indima ku-psoriasis.

Ngabe i-biologics isetshenziswa nini?

Esikhathini esedlule, i-biologics yayingasetshenziswanga ngaphandle kokuthi ezinye izindlela zokwelapha bezingasebenzi. Izidakamizwa ezingezona ukuvuvukala (i-NSAID) kanye nezidakamizwa zokuguqula izifo (i-DMARD) kungenzeka zinqunywe kuqala.

Kepha imihlahlandlela emisha incoma ukusebenzisa i-biologics njengokwelashwa komugqa wokuqala kwe-PsA. Ngokuya ngezimpawu zakho ze-psoriatic arthritis kanye nomlando wezokwelapha, udokotela wakho angancoma enye ye-biologics eziningana ukuze kutholakale usizo.

Ngubani ofanelekela i-biologics?

Kunconywa ukuthi i-tumor necrosis factor inhibitor (TNFi) biologics isetshenziswe njengenketho yokwelashwa komugqa wokuqala kubantu abane-PsA esebenzayo, okusho ukuthi i-PsA okwamanje edala izimpawu.

Imihlahlandlela emisha evela e-American College of Rheumatology kanye ne-National Psoriasis Foundation nayo incoma ukuzama i-TNFis kuqala kubantu abangazange basebenzise ezinye izindlela zokwelapha ngaphambili.

Uhlelo lwakho lokwelashwa lomuntu ngamunye luzonqunywa ukuthi iPSA yakho inzima kangakanani. Ayikho indlela ethembekile yokuthola ukuthi i-PsA inzima kangakanani iyodwa. Udokotela wakho kungenzeka ahlukanise ukuthi iPSA yakho inamandla kangakanani ngokuya ngokuthi i-psoriasis yakho inzima kangakanani. Izindlela ezimbili odokotela abalinganisa ubunzima be-psoriasis zifaka izinkomba ezingezansi.

Indawo ye-Psoriasis Area and Severity Index (PASI)

Isilinganiso se-PASI sinqunywa ngamaphesenti esikhumba sakho esithintwe yi-psoriasis. Lokhu kuncike ekutheni umzimba wakho unamabala angakanani. Ama-plaque ayizigaxa zesikhumba esikhuphukile, esinamaxolo, esilumayo, esomile nesibomvu.

Udokotela wakho uzonquma isilinganiso sakho se-PASI ngaphambi nangesikhathi sokwelashwa. Umgomo wokwelashwa ukubona ukunciphisa amaphesenti angama-50 kuya kwangu-75 kumaphuzu akho e-PASI.

I-Dermatology Quality of Life Index (DQLI)

Ukuhlolwa kwe-DQLI kubheka umphumela we-psoriasis enhlalakahleni yomuntu ngokomzimba, ngokwengqondo nangokomphakathi.

Isilinganiso se-DQLI sika-6 kuya ku-10 sisho ukuthi i-psoriasis yakho inomthelela olinganiselayo enhlalakahleni yakho. Amaphuzu angaphezu kuka-10 asho ukuthi isimo sinomthelela omkhulu enhlalakahleni yakho.

Udokotela wakho futhi anganquma ukuthi ufanele yini ukuthola i-biologics uma une-peripheral or axial psoriatic arthritis.

I-Peripheral psoriatic arthritis

I-peripheral psoriatic arthritis ibangela ukuvuvukala kwamalunga ezingalweni nasemilenzeni yakho. Lokhu kufaka phakathi:

• Izindololwane
• izihlakala
• izandla
• izinyawo

I-biologic ethile oyibekiwe incike ebukhulwini bezimpawu zakho. Kepha i-infliximab (i-Remicade) noma i-adalimumab (i-Humira) iyona khetho oluthandayo lapho udinga nokulawulwa okusheshayo kwe-psoriasis yesikhumba.

I-axial psoriatic arthritis

I-Axial psoriatic arthritis ibangela ukuvuvukala kwamalunga ezindaweni ezilandelayo:

• umgogodla
• okhalweni
• emahlombe

Ubani ongafaneleki ku-biologics?

Akuwona wonke umuntu ofanele ukwelashwa nge-biologics. Isibonelo, akufanele uthathe i-biologics uma ukhulelwe noma uncelisa. Ezimweni eziningi, nawe akufanele uthathe i-biologics uma une:

• ukutheleleka okungathi sína noma okusebenzayo
• isifo sofuba
• I-HIV noma i-hepatitis, ngaphandle uma isimo sakho silawulwa kahle
• umdlavuza noma nini eminyakeni eyishumi edlule

Uma i-biologics kungeyona inketho ekufanele, udokotela wakho angacabangela eminye imithi, njengezidakamizwa zokuguqula izifo (i-DMARDs) eziguqula izifo.

Ukuthatha

Ukuthola ukwelashwa kwe-PsA kungakulethela ukukhululeka okudingekayo ezimpawu ezibuhlungu. I-Biologics yimithi enamandla engasiza ekwelapheni iPSA. Kungaba yindlela ongayikhetha uma une-PsA elinganiselayo noma enamandla, i-peripheral psoriatic arthritis, noma i-axial psoriatic arthritis.

Qiniseka ukuthi utshela udokotela wakho ngazo zonke izimpawu zakho nokuthi i-PsA iyithinta kanjani impilo yakho. Udokotela wakho uzosebenzela ukukuthola ukwelashwa okufanele.