I-Lactic acidosis

I-Lactic acidosis ibhekisa ku-lactic acid eyakheke egazini. I-Lactic acid ikhiqizwa lapho amazinga e-oxygen, eba ngamaseli aphansi ngaphakathi kwezindawo zomzimba lapho kwenzeka khona imetabolism.

Isizathu esivame kakhulu se-lactic acidosis yisifo esibi sezokwelapha lapho umfutho wegazi uphansi futhi umoya-mpilo omncane ufinyelela izicubu zomzimba. Ukuvivinya umzimba kakhulu noma ukudlikizela kungadala imbangela yesikhashana ye-lactic acidosis. Izifo ezithile zingadala lesi simo kufaka:

• Ingculaza
• Ukuphuza ngokweqile
• Umdlavuza
• Isifo sokuqina kwesibindi
• Ubuthi be-cyanide
• Ukuhluleka kwezinso
• Ukwehluleka kokuphefumula
• I-Sepsis (ukutheleleka okunzima)

Eminye imithi ayivamile ukudala i-lactic acidosis:

• Amanye ama-inhaler asetshenziselwa ukwelapha i-asthma noma i-COPD
• I-Epinephrine
• I-antibiotic ebizwa nge-linezolid
• I-Metformin, esetshenziselwa ukwelapha isifo sikashukela (imvamisa lapho isetshenziswe ngokweqile)
• Uhlobo olulodwa lomuthi osetshenziselwa ukwelapha ukutheleleka nge-HIV
• I-Propofol

Izimpawu zingafaka:

• Isicanucanu
• Ukuhlanza
• Ubuthakathaka

Ukuhlolwa kungafaka ukuhlolwa kwegazi ukuhlola amazinga e-lactate ne-electrolyte.

Ukwelashwa okuyinhloko kwe-lactic acidosis ukulungisa inkinga yezokwelapha edala isimo.

I-Palmer BF. I-Metabolic acidosis. Ku: Feehally J, Floege J, Tonelli, Johnson RJ, abahleli. I-Nephrology Yomtholampilo Ephelele. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2019: isahluko 12.

Seifter JL. Izinkinga ze-acid-base. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 118.

I-Strayer RJ. Izinkinga ze-acid-base. Ku: Walls RM, Hockberger RS, Gausche-Hill M, et al, ama-eds. Imithi Ephuthumayo yaseRosen: Imiqondo kanye Nokuzijwayeza Komtholampilo. Umhlaka 9. IPhiladelphia, PA: Elsevier Saunders; 2018: isahluko 116.