Ifa elliptocytosis

IHereditary elliptocytosis yisifo esidluliswa emindenini lapho amangqamuzana abomvu egazi abunjwe ngokungajwayelekile. Iyafana nezinye izimo zegazi ezifana ne-spherocytosis yefa kanye ne-ovalocytosis yefa.

I-Elliptocytosis ithinta cishe umuntu oyedwa kwabangu-2 500 befa lasenyakatho neYurophu. Kuvame kakhulu kubantu abadabuka e-Afrika naseMedithera. Kungenzeka ukuthi usethuthukise lesi simo uma othile emndenini wakho enaso.

Izimpawu zingafaka:

• Ukukhathala
• Ukuphelelwa umoya
• Isikhumba esiphuzi namehlo (i-jaundice). Ingaqhubeka isikhathi eside enganeni esanda kuzalwa.

Ukuhlolwa ngumhlinzeki wakho wezokunakekelwa kwempilo kungakhombisa ubende obukhulisiwe.

Imiphumela elandelayo yokuhlola ingasiza ukuxilonga isimo:

• Izinga leBilirubin lingaphakama.
• I-smear yegazi ingakhombisa amangqamuzana egazi abomvu ayisiyingi.
• Ukubalwa kwegazi okuphelele (i-CBC) kungakhombisa ukushoda kwegazi noma izimpawu zokubhujiswa kwamaseli abomvu.
• Izinga le-lactate dehydrogenase lingaphakama.
• Ukucabanga nge-gallbladder kungakhombisa amatshe enyongo.

Alukho ukwelashwa oludingekayo kulesi sifo ngaphandle kokuthi kuvele izimpawu ezinzima zokushoda kwegazi noma kwegazi. Ukuhlinzwa ukususa ubende kunganciphisa izinga lokulimala kwamangqamuzana egazi abomvu.

Iningi labantu abane-elliptocytosis yefa abanazinkinga. Imvamisa abazi ukuthi banesimo.

I-Elliptocytosis kaningi ayinabungozi. Ezimweni ezimnene, angaphansi kuka-15% amangqamuzana abomvu egazi anomumo okwe-elliptical. Kodwa-ke, abanye abantu bangaba nezinkinga lapho kuqhuma khona amaseli abomvu egazi. Lokhu kungenzeka kakhulu uma benesifo segciwane. Abantu abanalesi sifo bangaba ne-anemia, jaundice, ne-gallstones.

Shayela umhlinzeki wakho uma une-jaundice engapheli noma izimpawu ze-anemia noma i-gallstones.

Ukwelulekwa ngofuzo kungafaneleka kubantu abanomlando womndeni walesi sifo abafisa ukuba ngabazali.

I-Elliptocytosis - ifa

• Amaseli abomvu egazi - i-elliptocytosis
• Amaseli egazi

IGallagher PG. Ama-anemia we-hemolytic: ulwelwesi lwegazi elibomvu nokukhubazeka komzimba. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 152.

IGallagher PG. Ukuphazamiseka kwamangqamuzana egazi abomvu. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 45.

IMerguerian MD, iGallagher PG. I-elliptocytosis eyifa, ifa le-pyropoikilocytosis, kanye nokuphazamiseka okuhlobene nako. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahluko 486.