Meningitis - i-cryptococcal

I-Cryptococcal meningitis yigciwane lesikhunta lezicubu ezihlanganisa ubuchopho nomgogodla. Lezi zicubu zibizwa ngokuthi ama-meninges.

Ezimweni eziningi, i-cryptococcal meningitis ibangelwa isikhunta I-Cryptococcus neoformans. Le fungus itholakala enhlabathini emhlabeni jikelele. I-Cryptococcus gattii futhi kungadala i-meningitis, kepha leli fomu lingadala nezifo ezigulini ezinamasosha omzimba ajwayelekile.

Lolu hlobo lwe-meningitis alusabalaliswa lusuka kumuntu luye komunye. Imvamisa, isakazeka emgudwini wegazi iye ebuchosheni isuka kwenye indawo emzimbeni onesifo.

I-Cryptococcus neoformans i-meningitis ivame ukuthinta abantu abanamasosha omzimba abuthakathaka, kufaka phakathi abantu abane-:

• Ingculaza
• I-Cirrhosis (uhlobo lwesifo sesibindi)
• Isifo sikashukela
• Umdlavuza wegazi
• I-Lymphoma
• I-Sarcoidosis
• Ukufakelwa komzimba

Lesi sifo asivamile kubantu abanamasosha omzimba ajwayelekile futhi abanazinkinga zempilo zesikhathi eside.

Leli fomu le-meningitis liqala kancane, ngaphezu kwezinsuku ezimbalwa kuya emasontweni ambalwa. Izimpawu zingafaka:

• Imfiva
• Ukusangana
• Ubuhlungu bekhanda
• Ukushintsha kwesimo sengqondo (ukudideka)
• Isicanucanu nokuhlanza
• Ukuzwela ekukhanyeni
• Intamo eqinile

Umhlinzeki wakho wokunakekelwa kwezempilo uzokuhlola abuze ngezimpawu zakho.

Ukubhoboza i-lumbar (umpompi womgogodla) kusetshenziselwa ukuxilonga i-meningitis. Kulesi sivivinyo, isampula le-cerebrospinal fluid (CSF) liyasuswa emgogodleni wakho bese liyahlolwa.

Olunye uvivinyo olungenziwa lubandakanya:

• Isiko legazi
• I-x-ray yesifuba
• I-antigen ye-Cryptococcal ku-CSF noma igazi, ukufuna amasosha omzimba
• Ukuhlolwa kwe-CSF kokubalwa kwamaseli, i-glucose, namaprotheni
• I-CT scan yekhanda
• Ibala le-Gram, amanye amabala akhethekile, namasiko e-CSF

Imithi yokubulala amagciwane isetshenziselwa ukwelapha lolu hlobo lwe-meningitis. Ukwelashwa ngomjovo (IV, ngokusebenzisa umthambo) nge-amphotericin B ukwelashwa okuvame kakhulu. Kuvame ukuhlanganiswa nomuthi we-antifungal womlomo obizwa nge-5-flucytosine.

Esinye isidakamizwa somlomo, i-fluconazole, ngemithamo ephezulu singasebenza futhi. Uma kudingeka, izonqunywa ngokuhamba kwesikhathi esifundweni sesifo.

Abantu abalulama kwi-cryptococcal meningitis badinga umuthi wesikhathi eside ukuvimbela ukutheleleka ekubuyeni. Abantu abanamasosha omzimba abuthakathaka, njengalabo abane-HIV / AIDS, bazodinga nokwelashwa isikhathi eside ukwenza ngcono amasosha omzimba.

Lezi zinkinga zingavela kulokhu kutheleleka:

• Ukulimala kobuchopho
• Ukuzwa noma ukulahleka kombono
• I-Hydrocephalus (i-CSF eyeqile ebuchosheni)
• Ukuquleka
• Ukufa

I-Amphotericin B ingaba nemiphumela emibi efana nale:

• Isicanucanu nokuhlanza
• Umkhuhlane namakhaza
• Ubuhlungu obuhlangene nemisipha
• Ukulimala kwezinso

Shayela inombolo yakho yendawo ephuthumayo (efana ne-911) uma uba nezimpawu ezinzima ezibhalwe ngenhla. I-meningitis ngokushesha ingaba isifo esongela impilo.

Shayela inombolo yakho yendawo ephuthumayo noma uye egumbini lezimo eziphuthumayo uma usola i-meningitis enganeni encane enalezi zimpawu:

• Ukondla ubunzima
• Ukukhala okuphezulu
• Ukuthukuthela
• Umkhuhlane oqhubekayo, ongachazeki

I-Cryptococcal meningitis

• Isistimu yezinzwa emaphakathi nesistimu yezinzwa ezungezayo

Izikhungo Zokulawulwa Nokuvimbelwa Kwezifo iwebhusayithi. I-fungal meningitis. www.cdc.gov/meningitis/fungal.html. Kubuyekezwe u-Agasti 06, 2019. Kufinyelelwe ngoFebhuwari 18, 2021.

IKauffman CA, Chen S. Cryptococcosis. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 317.

I-JR ephelele. I-Cryptococcosis (I-Cryptococcus neoformans futhi I-Cryptococcus gattii). Ku: Bennett JE, Dolin R, Blaser MJ, ama-eds. Mandell, Douglas, kanye neBennett's Principles and Practice of Infectious Diseases. Umhlaka 9. IPhiladelphia, PA: Elsevier; 2020: isahluko 262.