Isimila se-Hypothalamic

Isigaxa se-hypothalamic ukukhula okungajwayelekile ku-hypothalamus gland, etholakala ebuchosheni.

Isizathu esiqondile samathumba we-hypothalamic asaziwa. Kungenzeka ukuthi zibangelwa inhlanganisela yezici zofuzo nezemvelo.

Ezinganeni, izicubu eziningi ze-hypothalamic ngama-gliomas. Ama-gliomas awuhlobo oluvamile lwesimila sobuchopho esivela ekukhuleni okungavamile kwamaseli we-glial, asekela amangqamuzana ezinzwa. Ama-gliomas angenzeka nganoma yisiphi isikhathi. Zivame ukuba nolaka kubantu abadala kunezingane.

Kubantu abadala, izicubu ku-hypothalamus kungenzeka ukuthi umdlavuza osakazeke usuka kwesinye isitho.

Abantu abane-neurofibromatosis (isimo sofuzo) basengozini enkulu yalolu hlobo lwesimila. Abantu abathole ukwelashwa ngemisebe basengozini enkulu yokuthola izicubu ngokujwayelekile.

Lezi zicubu zingadala uhla lwezimpawu:

• Imizwa ye-Euphoric "ephezulu"
• Ukwehluleka ukuchuma (ukungabi nokukhula okujwayelekile ezinganeni)
• Ubuhlungu bekhanda
• Ukungasebenzi kahle
• Ukulahleka kwamafutha omzimba nokudla (cachexia)

Lezi zimpawu zivame ukubonakala ezinganeni ezinamathumba athinta ingxenye engaphambili ye-hypothalamus.

Ezinye izicubu zingadala ukulahleka kombono. Uma izicubu zivimba ukugeleza koketshezi lomgogodla, ukuphathwa ikhanda nokulala kungavela ekuqoqeni uketshezi ebuchosheni (i-hydrocephalus).

Abanye abantu bangaba nokuquleka ngenxa yezicubu zobuchopho. Abanye abantu bangaqala ukuthomba besengcupheni yokushintshwa kokusebenza kwendlala yendlala.

Umhlinzeki wakho wokunakekelwa kwezempilo angabona izimpawu zesimila se-hypothalamic ngesikhathi sokuhlolwa okuvamile. Ukuhlolwa kobuchopho kanye nesistimu yezinzwa (i-neurological), kufaka phakathi ukuhlolwa komsebenzi wokubuka, kungenziwa. Ukuhlolwa kwegazi kokungalingani kwamahomoni nakho kunga-oda.

Ngokuya ngemiphumela yokuhlolwa nokuhlolwa kwegazi, ukuskena kwe-CT noma i-MRI scan kunganquma ukuthi unesimila se-hypothalamic.

Ukuhlolwa kwensimu ebonakalayo kungenziwa ukubheka ukulahleka kombono nokuthola ukuthi isimo siyathuthuka noma siya ngokuya siba sibi.

Ukwelashwa kuya ngokuthi isilonda sinolaka kangakanani, nokuthi ngabe yiglioma noma olunye uhlobo lomdlavuza. Ukwelashwa kungabandakanya inhlanganisela yokuhlinzwa, ukukhishwa kwemisebe nokwelashwa ngamakhemikhali.

Imithi ekhethekile yokwelashwa ngemisebe ingagxila kuthumba. Zingasebenza njengokuhlinzwa, zingabi nengozi encane yezicubu ezizungezile. Ukuvuvukala kobuchopho okubangelwa isimila kungadinga ukwelashwa nge-steroids.

Izicubu ze-Hypothalamic zingaveza ama-hormone noma zithinte ukukhiqizwa kwamahomoni, okuholele ekungalingani okungadinga ukulungiswa. Kwezinye izimo, ama-hormone angadinga ukushintshwa noma anciphiswe.

Imvamisa ungasiza ukucindezela kokugula ngokujoyina iqembu lokwesekwa lapho amalungu abelana ngokuhlangenwe nakho okuvamile nezinkinga.

Umbono uncike ku:

• Uhlobo lwesimila (i-glioma noma olunye uhlobo)
• Indawo yesimila
• Ibanga lesimila
• Usayizi wesimila
• Iminyaka yakho nempilo ejwayelekile

Ngokuvamile, i-gliomas kubantu abadala inolaka kakhulu kunezingane futhi imvamisa iba nemiphumela emibi kakhulu. Izicubu ezibangela i-hydrocephalus zingadala izinkinga eziningi, futhi zingadinga ukuhlinzwa.

Izinkinga zokuhlinzwa kobuchopho zingafaka:

• Ukopha
• Ukulimala kobuchopho
• Ukufa (kuyaqabukela)
• Ukutheleleka

Ukuquleka kungabangelwa isimila noma kunoma iyiphi inqubo yokuhlinzwa ebuchosheni.

IHydrocephalus ingenzeka ngezinye izicubu futhi ingadinga ukuhlinzwa noma ipayipi elibekwe ebuchosheni ukunciphisa ingcindezi yomgogodla.

Izingozi zokwelashwa ngemisebe zifaka phakathi ukulimala kwamangqamuzana obuchopho anempilo lapho kubhujiswa amaseli ezimila.

Imiphumela emibi ejwayelekile evela ekhemotherapy ihlanganisa ukulahlekelwa isifiso sokudla, isicanucanu nokuhlanza nokukhathala.

Shayela umhlinzeki wakho uma wena noma ingane yakho niba nezimpawu zesimila se-hypothalamic. Ukuhlolwa njalo kwezokwelapha kungathola izimpawu zokuqala zenkinga, njengokuzuza ngokweqile kwesisindo noma ukuthomba ngaphambi kwesikhathi.

I-Hypothalamic glioma; Hypothalamus - isimila

UGoodden J, uMallucci C. Optic wendlela yama-hypothalamic gliomas. Ku: Winn HR, ed. Ukuhlinzwa Kwe-Youmans neWinn Neurological. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2017: isahluko 207.

I-Weiss RE. I-Neuroendocrinology kanye nohlelo lwe-neuroendocrine. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 210.