Ukuhlolwa kwegazi le-Gamma-glutamyl transferase (GGT)

Ukuhlolwa kwegazi kwe-gamma-glutamyl transferase (GGT) kukala izinga le-enzyme GGT egazini.

Kudingeka isampula yegazi.

Umhlinzeki wezempilo angakutshela ukuthi uyeke ukuthatha imishanguzo engathinta ukuhlolwa.

Izidakamizwa ezingakhuphula izinga le-GGT zifaka:

• Utshwala
• Phenytoin
• I-Phenobarbital

Izidakamizwa ezinganciphisa izinga le-GGT zifaka:

• Amaphilisi okuvimbela inzalo
• Clofibrate

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

I-GGT iyi-enzyme etholakala ezingeni eliphakeme esibindini, ezinso, amanyikwe, inhliziyo nobuchopho. Kutholakala nenani elincane kwezinye izicubu. I-enzyme yiprotheni edala ushintsho oluthile lwamakhemikhali emzimbeni.

Lokhu kuhlolwa kusetshenziselwa ukuthola izifo zesibindi noma zemibhobho yenyongo. Kwenziwa futhi ngezinye izivivinyo (njenge-ALT, AST, ALP, kanye nokuhlolwa kwe-bilirubin) ukutshela umehluko phakathi kokuphazamiseka kwesibindi noma kwe-bile duct kanye nesifo samathambo.

Kungase kwenziwe futhi ukuhlola, noma ukuqapha, ukusetshenziswa kotshwala.

Ububanzi obujwayelekile babantu abadala ngu-5 kuya ku-40 U / L.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezihlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga le-GGT elandisiwe lingahle libangelwe ngenxa yalokhu okulandelayo:

• Ukusetshenziswa kotshwala
• Isifo sikashukela
• Ukugeleza kwe-bile kusuka esibindi kuvinjelwe (cholestasis)
• Ukwehluleka kwenhliziyo
• Isibindi sokuvuvukala esivuthayo (hepatitis)
• Ukuntuleka kokugeleza kwegazi kuye esibindini
• Ukufa kwezicubu zesibindi
• Umdlavuza wesibindi noma isimila
• Isifo samaphaphu
• Isifo samanyikwe
• Ukuqubuka kwesibindi (i-cirrhosis)
• Ukusetshenziswa kwezidakamizwa ezinobuthi esibindini

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane kepha zingafaka:

• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-Hematoma (ukuqoqa igazi ngaphansi kwesikhumba)
• Ukopha ngokweqile
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-Gamma-GT; I-GGTP; I-GGT; I-Gamma-glutamyl transpeptidase

IChernecky CC, iBerger BJ. I-Gamma-glutamyltranspeptidase (GGTP, gamma-glutamyltransferase) - igazi. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 559-560.

IPratt DS. I-chemistry yesibindi nokuhlolwa kokusebenza. Ku: Feldman M, Friedman LS, Brandt LJ, ama-eds. Sleisenger kanye neFordtran's Gastrointestinal and Liver Disease. Umhlaka 10. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 73.