Ukuhlolwa kwegazi kweMethylmalonic acid

Ukuhlolwa kwegazi kwe-methylmalonic acid kukala inani le-methylmalonic acid egazini.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile okudingekayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

I-Methylmalonic acid yinto ekhiqizwa lapho amaprotheni, abizwa ngama-amino acid, emzimbeni ephuka.

Umhlinzeki wezokunakekelwa kwempilo anga-oda lokhu kuhlolwa uma kunezimpawu ezithile zokuphazamiseka kofuzo, njenge-methylmalonic acidemia. Ukuhlolwa kwalesi sifo kuvame ukwenziwa njengengxenye yokuhlolwa kokuzalwa kwezingane ezisanda kuzalwa.

Lokhu kuhlolwa kungenziwa futhi nezinye izivivinyo ukuhlola ukushoda kukavithamini B12.

Amanani ajwayelekile angama-micromoles ayi-0.07 kuya ku-0.27 ilitha ngalinye.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Inani eliphakeme kunokujwayelekile lingahle libangelwe ukuntuleka kwe-vitamin B12 noma i-methylmalonic acidemia.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukopha ngokweqile
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

• Ukuhlolwa kwegazi

U-Antony AC. Ama-anemias we-Megaloblastic. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 39.

I-Elghetany MT, iSchexneider KI, ukuphazamiseka kwe-Banki K. Erythrocytic. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 32.