Ukuboshwa kwe-CSF oligoclonal

I-CSF oligoclonal banding isivivinyo sokubheka amaprotheni ahlobene nokuvuvukala ku-cerebrospinal fluid (CSF). I-CSF iwuketshezi olucacile olugeleza esikhaleni esizungeze intambo yomgogodla nobuchopho.

Ama-oligoclonal band angamaprotheni abizwa ngama-immunoglobulins. Ukuba khona kwala maprotheni kukhombisa ukuvuvukala kwesistimu yezinzwa emaphakathi. Ukuba khona kwama-oligoclonal band kungakhomba ekutholakaleni kwe-multiple sclerosis.

Isampula le-CSF liyadingeka. Ukubhoboza i-lumbar (umpompi womgogodla) kuyindlela ejwayelekile kakhulu yokuqoqa lesi sampula.

Ezinye izindlela zokuqoqa i-CSF zivame ukusetshenziswa, kepha zinganconywa kwezinye izimo. Kubandakanya:

• Ukubhoboza umthombo
• Ukubhoboza okubonakalayo
• Ukususwa kwe-CSF kushubhu esivele iku-CSF, efana ne-shunt noma i-ventricular drain.

Ngemuva kokuthi kuthathwe isampula, ithunyelwa ebhodini ukuze ihlolwe.

Lokhu kuhlolwa kusiza ukusekela ukuxilongwa kwe-multiple sclerosis (MS). Noma kunjalo, akuqinisekisi ukuxilongwa. Amaqembu e-Oligoclonal ku-CSF angabonakala nakwezinye izifo ezinjenge:

• Uhlelo lupus erythematosus
• Ukutheleleka ngegciwane lesandulela ngculaza (i-HIV)
• Unhlangothi

Imvamisa, ibhande elilodwa noma cha kufanele litholakale ku-CSF.

Qaphela: Amabanga wamanani ajwayelekile angahluka kancane kumalabhorethri ahlukile. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izibonelo ezingenhla zibonisa izilinganiso ezivamile zemiphumela yalezi zivivinyo. Amanye ama-laboratories asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezahlukene.

Kunamabhande amabili noma ngaphezulu atholakala kwi-CSF hhayi egazini. Lokhu kungaba uphawu lwe-multiple sclerosis noma okunye ukuvuvukala.

Uketshezi lweCerebrospinal - i-immunofixation

• I-CSF oligoclonal banding - uchungechunge
• Ukubhoboza i-Lumbar (umpompi womgogodla)

UDeluca GC, uGriggs RC. Indlela eya esigulini esinesifo se-neurologic. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 368.

IKarcher DS, iMcPherson RA. I-Cerebrospinal, synovial, uketshezi lomzimba we-serous, nezinye izinhlobo. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 29.