Ukufakwa Kwe-Histrelin

-Delile

• Ngaphambi kokuthola ukufakwa kwe-histrelin,
• Ukufakwa kwe-Histrelin kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

Ukufakwa kwe-Histrelin (Vantas) kusetshenziselwa ukwelapha izimpawu ezihambisana nomdlavuza wesibeletho osezingeni eliphakeme. Ukufakwa kwe-Histrelin (i-Supprelin LA) kusetshenziselwa ukwelapha ukuthomba okuyisisekelo (CPP; isimo esidala ukuthi izingane zikwazi ukungena ebusheni ngokushesha okukhulu, okuholela ekukhuleni okusheshayo kunokukhula kwethambo nokuthuthuka kwezici zobulili) emantombazaneni ngokuvamile aneminyaka ephakathi kwengu-2 nengu-8 ubudala futhi kubafana ngokuvamile abaneminyaka ephakathi kwengu-2 nengu-9 ubudala. Ukufakwa kwe-Histrelin kusekilasini lemithi ebizwa nge-gonadotropin-releasing hormone (GnRH) agonists. Isebenza ngokunciphisa inani lamahomoni athile emzimbeni.

I-Histrelin iza njengokufakwa (ithubhu elincane, elincane, eliguquguqukayo eliqukethe umuthi) elifakwa ngudokotela ngaphakathi kwengalo ephezulu. Udokotela uzosebenzisa umuthi ukunqanda ingalo, enze ukusika okuncane esikhunjeni, bese efaka okufakelwa ngaphansi kwesikhumba). I-cut izovalwa ngemithungo noma imichilo yokuhlinzwa futhi imbozwe ngebhandeshi. Ukufakwa kungafakwa njalo ezinyangeni eziyi-12. Ngemuva kwezinyanga eziyi-12, ukufakelwa kwamanje kufanele kususwe futhi kungashintshwa okunye ukufakelwa ukuqhubeka nokwelashwa. Ukufakwa kwe-Histrelin (Supprelin LA) lapho kusetshenziswa ezinganeni ezinokuthomba ngaphambi kwesikhathi, kungenzeka kumiswe udokotela wengane yakho ngaphambi kweminyaka engu-11 emantombazaneni neminyaka engu-12 kubafana.

Gcina indawo ezungeze ukufakelwa ihlanzekile futhi yomile amahora angama-24 ngemuva kokufakwa. Ungabhukudi noma ugeze ngalesi sikhathi. Shiya ibhandishi endaweni okungenani amahora angama-24. Uma kusetshenziswa imichilo yokuhlinzwa, bayeke baqhubeke baze baziwele bodwa. Gwema ukuphakamisa okunzima nokusebenza ngokomzimba (kufaka phakathi ukudlala okunzima noma ukuzivocavoca izingane) ngengalo ephathekayo izinsuku eziyi-7 ngemuva kokuthola okufakelwayo. Gwema ukushayisa indawo ezungeze ukufakelwa izinsuku ezimbalwa ngemuva kokufakwa.

I-Histrelin ingadala ukwanda kwamahomoni athile emasontweni ambalwa okuqala ngemuva kokufakwa kokufakwa. Udokotela wakho uzokuqapha ngokucophelela nganoma yiziphi izimpawu ezintsha noma eziba nzima ngalesi sikhathi.

Kwesinye isikhathi ukufakwa kwe-histrelin kunzima ukuzizwa ngaphansi kwesikhumba ngakho-ke udokotela kungadingeka asebenzise izivivinyo ezithile, ezinjenge-ultrasound noma i-MRI scan (amasu e-radiology aklanyelwe ukukhombisa izithombe zezakhiwo zomzimba) ukuthola okufakiwe lapho sekuyisikhathi sokukususa. Kwesinye isikhathi, ukufakelwa kwe-histrelin kungahle kuphume kusayithi lokuqala lokufaka kukodwa. Ungakubona noma ungakuboni lokhu kwenzeka. Shayela udokotela wakho ngokushesha uma ucabanga ukuthi lokhu kungenzeka kuwe.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola ukufakwa kwe-histrelin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-histrelin, goserelin (Zoladex), leuprolide (Eligard, Lupaneta Pack, Lupron), nafarelin (Synarel), triptorelin (Trelstar, Triptodur Kit), izinzwa ezifana ne-lidocaine (Xylocaine), noma iyiphi enye imithi, noma iziphi izithako ekufakweni kwe-histrelin. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: amiodarone (Nexterone, Pacerone), anagrelide (Agrylin), bupropion (Aplenzin, Forfivo, Wellbutrin, Zyban, in Contrave), chloroquine, chlorpromazine, cilostazol, ciprofloxacin (Cipro), citalopram (Celexa) , Clarithromycin, disopyramide (Norpace), dofetilide (Tikosyn), donepezil (Aricept), dronedarone (Multaq), escitalopram (Lexapro), flecainide (Tambocor), fluconazole (Diflucan), fluoxetine (Prozac, Sarafemya, Selfemra i-fluvoxamine (i-Luvox), i-haloperidol (i-Haldol), i-ibutilide (i-Corvert), i-levofloxacin, i-methadone (i-Dolophine, i-Methadose), i-moxifloxacin (i-Avelox), i-ondansetron (i-Zuplenz, i-Zofran), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexevaine) i-pimozide (i-Orap), i-procainamide, i-quinidine (e-Nuedexta), i-sertraline (i-Zoloft), i-sotalol (i-Betapace, i-Sorine, i-Sotylize), i-thioridazine, i-vilazodone (i-Viibryd), ne-vortioxetine (i-Trintellix). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-histrelin, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• tshela udokotela wakho uma unezinga eliphansi le-potassium noma i-magnesium egazini lakho. noma uma uke waba nesifo sikashukela, umfutho wegazi ophakeme, i-cholesterol ephezulu, isikhawu se-QT eside (inkinga yenhliziyo engajwayelekile engadala ukushaya kwenhliziyo, ukuquleka, noma ukufa okungazelelwe), umdlavuza osakaze emgogodleni (umgogodla), ukuvinjelwa komchamo (ukuvinjelwa okubangela ubunzima bokuchama), ukuxhuzula, ubuchopho noma izinkinga zemithambo yegazi noma izicubu, ukugula kwengqondo, noma isifo senhliziyo.
• kufanele wazi ukuthi i-histrelin akufanele isetshenziswe kwabesifazane abakhulelwe noma abangakhulelwa. Tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ucabanga ukuthi ukhulelwe ngenkathi uthola ukufakwa kwe-histrelin, shayela udokotela wakho ngokushesha. Ukufakwa kwe-Histrelin kungalimaza umbungu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa i-aphoyintimenti yokwamukela ukufakwa kwe-histrelin noma ukukhishwa kwe-histrelin, kufanele ushayele umhlinzeki wakho wezokunakekelwa kwezempilo khona manjalo ukusetha kabusha isikhathi sakho. Uma kuqhubeka ukwelashwa, ukufakwa okusha kwe-histrelin kufanele kufakwe emasontweni ambalwa.

Ukufakwa kwe-Histrelin kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukulimaza, ukuba buhlungu, ukuqaqamba, noma ukulunywa lapho kufakwe khona ukufakelwa
• isibazi lapho kufakwe khona ukufakelwa
• ukushisa okushisayo (ukuqhuma okungazelelwe kokushisa komzimba okuncane noma okukhulu)
• ukukhathala
• ukuphuma kwegazi esithweni sangasese emantombazaneni
• amabele akhulisiwe
• ukwehla ngosayizi wamasende
• kwehle ikhono lezocansi noma inzalo
• ukuqunjelwa
• ukuzuza kwesisindo
• ubunzima bokulala noma ukulala
• ikhanda
• ukukhala, ukucasuka, ukubekezela, intukuthelo, isimilo esinolaka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ubuhlungu, ukopha, ukuvuvukala, noma ubomvu endaweni lapho kufakwe khona ukufakwa
• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ubuhlungu bamathambo
• ubuthakathaka noma ukuba ndikindiki emilenzeni
• ubuhlungu, ukuvutha, noma ukuhayiza engalweni noma emlenzeni
• inkulumo ehamba kancane noma enzima
• isiyezi noma ukuquleka
• ubuhlungu besifuba
• ubuhlungu ezingalweni, emhlane, entanyeni, noma emhlathini
• ukulahlekelwa amandla okuhamba
• ukuchama okunzima noma awukwazi ukuchama
• igazi emchameni
• ukuncipha kokuchama
• ukopha okungajwayelekile noma ukulinyazwa
• ukukhathala ngokweqile
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuphuzi kwesikhumba noma kwamehlo
• izimpawu ezinjengomkhuhlane
• ukudana, ukucabanga ngokuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo
• isithuthwane

Ukufakwa kwe-Histrelin kungadala ushintsho emathanjeni akho angakhuphula amathuba okuphuka kwamathambo lapho esetshenziswa isikhathi eside. Khuluma nodokotela wakho ngezingozi zokuthola lo muthi.

Ezinganeni ezithola ukufakelwa kwe-histrelin (i-Supprelin LA) yokuthomba ngaphambi kwesikhathi, izimpawu ezintsha noma eziya ziba zimbi zokukhula kocansi kungenzeka emasontweni ambalwa okuqala ngemuva kokufakwa kokufakwa. Emantombazaneni athola ukufakwa kwe-histrelin (i-Supprelin LA) yokuthomba ngaphambi kwesikhathi, ukuphuma kwegazi lesitho sangasese sowesifazane noma ukukhulisa isifuba kungenzeka ngenyanga yokuqala yokwelashwa.

Ukufakwa kwe-Histrelin kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu futhi athathe izilinganiso ezithile ukuhlola impendulo yomzimba wakho ekufakweni kwe-histrelin. Ushukela wegazi kanye ne-hemoglobin yakho eglycosylated (HbA1c) kufanele ihlolwe njalo.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi unokufakelwa kwe-histrelin.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokufakwa kwe-histrelin.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Supprelin LA^®
• Vantas^®