I-Raltegravir

-Delile

• Ngaphambi kokuthatha i-raltegravir,
• IRaltegravir ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Raltegravir isetshenziswa kanye neminye imithi yokwelapha ukutheleleka ngegciwane lesandulela ngculaza (i-HIV) kubantu abadala nasezinganeni ezinesisindo okungenani esingu-4.5 lbs (2 kg). URaltegravir usesigabeni semithi ebizwa nge-HIV integrase inhibitors. Isebenza ngokunciphisa inani le-HIV egazini. Yize i-raltegravir ingayelaphi i-HIV, ingahle inciphise amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengezifo ezibucayi noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko endleleni yokuphila kunganciphisa ubungozi bokudlulisela (ukusabalalisa) igciwane le-HIV kwabanye abantu.

I-Raltegravir iza njengethebhulethi, ithebhulethi ehlafunwayo, nanjengezindilinga zokumiswa ngomlomo ezizothathwa ngomlomo. IRaltegravir (Isentress^®) amaphilisi, amaphilisi angahlaziyekiyo, nokumiswa ngomlomo kuvame ukuthathwa nokudla noma ngaphandle kokudla kabili ngosuku. IRaltegravir (Isentress^® Amaphilisi e-HD) avame ukuphuzwa nokudla noma ngaphandle kokudla kanye ngosuku. Thatha i-raltegravir ngasikhathi sinye (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-raltegravir njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze. Uma uphuza amaphilisi angahlafunwayo, ungawahlafuna noma uwagwinye wonke.

Ezinganeni ezinenkinga yokuhlafuna, amaphilisi angahlafunwayo angagaywa futhi ahlanganiswe nethisipuni elilodwa (5 ml) loketshezi njengamanzi, ujusi, noma ubisi lwebele enkomishini ehlanzekile. Amaphilisi azomunca uketshezi futhi awele phakathi nemizuzu emibili. Usebenzisa isipuni, gaya noma yiziphi izingcezu zamaphilisi ezisele. Phuza ingxube ngokushesha. Uma noma imuphi umuthi ushiywe enkomishini, engeza enye isipuni (5 ml) ketshezi, ujikeleze ulithathe khona manjalo.

Ngaphambi kokuba uthathe ukumiswa ngomlomo kwe-raltegravir okokuqala, funda imiyalelo ebhaliwe eza nayo echaza ukuthi ungayilungisa kanjani imithi. Sula konke okuqukethwe yiphakethe elilodwa le-granule enkomishini yokuxuba bese ufaka amathisipuni ama-2 (10 ml) wamanzi. Shayela ngomusa okuqukethwe enkomishini yokuxuba imizuzwana engama-45; unganyakazisi. Sebenzisa umjovo wokulinganisa okuhlinzekwe ukukala inani lemithi udokotela wakho akubekile. Sebenzisa ingxube kungakapheli imizuzu engu-30 yokulungiselela bese ulahla noma ikuphi ukumiswa okusele.

Qhubeka uthathe i-raltegravir noma ngabe uzizwa uphilile. Ungayeki ukuphuza i-raltegravir noma eminye imishanguzo elwa ne-HIV ngaphandle kokukhuluma nodokotela wakho. Uma uyeka ukuthatha i-raltegravir noma ukweqa imithamo, isimo sakho singase sibe sibi kakhulu futhi igciwane lingamelana nemithi.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-raltegravir,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-raltegravir, noma imuphi omunye umuthi, noma iziphi izithako emikhiqizweni ye-raltegravir. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi kokulandelayo: ama-antacids aqukethe i-calcium, i-magnesium, noma i-aluminium (Maalox, Mylanta, Tums, nokunye); i-carbamazepine (i-Equetro, iTegretol, iTeril); imithi yokwehlisa i-cholesterol (ama-statins) njenge-atorvastatin (Lipitor, eCaduet), i-fluvastatin (Lescol), i-lovastatin (i-Altoprev), i-pravastatin (i-Pravachol), i-rosuvastatin (i-Crestor), ne-simvastatin (i-Zocor, e-Vytorin); i-etravirine (Intelence); fenofibrate (Antara, Lipofen, Tricor, abanye); gemfibrozil (Lopid); i-phenobarbital; i-phenytoin (iDilantin, Phenytek); i-rifampin (i-Rifadin, i-Rimactane, e-Rifamate, e-Rifater), i-tipranavir (i-Aptivus) ene-ritonavir (i-Norvir); kanye ne-zidovudine (Retrovir, abanye). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma welashwa nge-dialysis (ukwelashwa ukuhlanza igazi lapho izinso zingasebenzi kahle), noma uma uke waba ne-hepatitis, i-cholesterol ephezulu yegazi noma i-triglycerides (izinto ezinamafutha egazini), isifo semisipha noma ukuvuvukala kwemisipha, noma i-rhabdomyolysis (isimo semisipha yamathambo).
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-raltegravir, shayela udokotela wakho. Tshela udokotela wakho uma uncelisa noma uhlela ukuncelisa. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma uthatha i-raltegravir.
• uma une-phenylketonuria (i-PKU, isimo esizuzwe njengefa lapho kufanele kulandelwe ukudla okhethekile ukuvimbela ukubambezeleka kwengqondo), kufanele wazi ukuthi amaphilisi angafuneki aqukethe i-aspartame eyakha i-phenylalanine.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi phakathi nokwelashwa kwakho nge-raltegravir.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi amaphilisi amabili e-raltegravir ngasikhathi sinye ukwenzela umthamo ongekho.

IRaltegravir ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• igesi
• ubuhlungu besisu
• isilungulela
• ukuqwasha
• amaphupho angajwayelekile
• ukudana
• ikhanda

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu bemisipha noma ubumnene
• ubuthakathaka bemisipha
• umchamo onombala omnyama noma kakhola
• ubuhlungu besifuba noma ingcindezi
• ukuqubuka
• imfiva
• amabhamuza esikhumba noma ukuxebuka
• isifuba
• ukulunywa
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, umphimbo, izandla, izinyawo, amaqakala noma izingalo
• ukuphefumula kanzima noma ukugwinya
• ukukhathala ngokweqile
• izilonda zomlomo
• amehlo abomvu, alumayo noma avuvukile
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuphuzi kwesikhumba noma kwamehlo
• indle ephaphathekile
• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• ukushaya kwenhliziyo okusheshayo
• ukuphelelwa umoya
• umkhuhlane, umphimbo obuhlungu, ukukhwehlela, ukugodola nezinye izimpawu zokutheleleka
• ukungabi namandla
• ukuzuza kwesisindo okungaqondakali
• ukuncipha kwenani lomchamo
• ukuvuvukala kuzungeze izinyawo, amaqakala, noma imilenze
• ukozela

I-Raltegravir ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungayikhiphi i-desiccant (iphakethe elincane elifakwe namathebulethi ukumunca umswakama) ebhodleleni lakho.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Gcina konke ukubonana nodokotela wakho kanye nelabhorethri ngenkathi uthatha i-raltegravir. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-raltegravir.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Isentress^®
• Isentress^® I-HD