I-Lurasidone

-Delile

• Ngaphambi kokuthatha i-lurasidone,
• ILurasidone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, noma lezo ezifakwe kuhlu KWEZIXWAYISO EZIBALULEKILE kanye NEZINYATHELO EZIKHETHEKILE, shayela udokotela wakho ngokushesha:

Isexwayiso esibalulekile kubantu abadala asebekhulile abanokuwohloka komqondo:

Ucwaningo lukhombisile ukuthi abantu abadala asebekhulile abanenkinga yokuwohloka komqondo (ukuphazamiseka kobuchopho okuthinta ikhono lokukhumbula, ukucabanga kahle, ukuxhumana, nokwenza imisebenzi yansuku zonke futhi lokho kungadala ushintsho esimweni sengqondo nobuntu) abathatha ama-antipsychotic (imishanguzo yokugula kwengqondo) njenge-lurasidone babe nethuba elandayo lokufa ngesikhathi sokwelashwa. Abantu abadala asebekhulile abanenkinga yokuwohloka komqondo futhi bangaba nethuba elikhulu lokuba nesifo sohlangothi noma i-ministroke ngenkathi belashwa ngama-antipsychotic.

ILurasidone ayivunyelwe yi-Food and Drug Administration (FDA) ekwelapheni ukuphazamiseka kokuziphatha kubantu abadala abanesifo sengqondo esiyingozi. Khuluma nodokotela onqume lo muthi uma wena, ilungu lomndeni, noma umuntu omnakekelayo enesifo sengqondo sokuphazamiseka ngokomqondo futhi ethatha i-lurasidone. Ngeminye imininingwane vakashela iwebhusayithi ye-FDA: http://www.fda.gov/Drugs

Isexwayiso esibalulekile kubantu abanokudangala:

Inani elincane lezingane, intsha, kanye nabantu abadala abancane (abangafika eminyakeni engama-24 ubudala) abathathe imishanguzo yokudangala ngesikhathi sezifundo zokwelashwa baba ukuzibulala (becabanga ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza njalo). Izingane, intsha, kanye nabantu abadala abasebancane abathatha imishanguzo yokulwisana nokucindezelwa ukwelapha ukudangala noma ezinye izifo zengqondo bangase babe sethubeni lokuzibulala kunezingane, intsha kanye nabantu abadala abangawasebenzisi ama-anti-depressants ukwelapha lezi zimo. Kodwa-ke, ochwepheshe abaqiniseki ngokuthi le ngozi ingakanani nokuthi kufanele icatshangelwe kangakanani ekunqumeni ukuthi ingane noma osemusha kufanele yini athathe i-anti-depressant. Izingane ezingaphansi kweminyaka eyishumi ubudala akufanele zivame ukuthatha i-lurasidone ukwelapha ukucindezeleka, kodwa kwezinye izimo, udokotela anganquma ukuthi i-lurasidone iyimithi engcono kakhulu yokwelapha isimo sengane.

Kufanele wazi ukuthi impilo yakho yengqondo ingashintsha ngezindlela ezingalindelekile lapho uthatha i-lurasidone ukwelapha ukudangala noma okunye ukugula kwengqondo noma ngabe ungumuntu omdala ongaphezu kweminyaka engama-24 ubudala. Ungase uzibulale, ikakhulukazi ekuqaleni kokwelashwa kwakho futhi nganoma yisiphi isikhathi lapho umthamo wakho wanda noma wehla. Wena, umndeni wakho, noma umnakekeli wakho kufanele ushayele udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ukucindezeleka okusha noma okuya kuba kubi; ukucabanga ngokuzilimaza noma ukuzibulala, noma ukuhlela noma ukuzama ukwenza kanjalo; ukukhathazeka ngokweqile; ukuyaluza; ukwethuka; ubunzima bokulala noma ukulala; isimilo esinolaka; ukucasuka; ukwenza ngaphandle kokucabanga; ukungahlaliseki okukhulu; nokuhlanya okungajwayelekile. Qiniseka ukuthi umndeni wakho noma umnakekeli wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukubiza udokotela uma ungakwazi ukuzifunela ukwelashwa wedwa.

Umhlinzeki wakho wezokunakekelwa kwempilo uzofuna ukukubona kaningi ngenkathi uthatha i-lurasidone, ikakhulukazi ekuqaleni kokwelashwa kwakho. Qiniseka ukuthi ugcina wonke ama-aphoyintimenti wokuvakashelwa ehhovisi nodokotela wakho.

Kungakhathaliseki ukuthi uneminyaka emingaki, ngaphambi kokuba uthathe i-anti-depressant, wena, umndeni wakho, noma umnakekeli wakho kufanele ukhulume nodokotela wakho ngezingozi nezinzuzo zokwelapha isimo sakho nge-anti-depressant noma ngezinye izindlela zokwelapha. Kufanele futhi ukhulume ngobungozi nezinzuzo zokungaselaphi isimo sakho. Kufanele wazi ukuthi ukuba nokudangala noma esinye isifo sengqondo kusandisa kakhulu ingozi yokuthi uzozibulala. Le ngozi iba phezulu uma wena noma omunye emndenini wakho unenkinga yokuphazamiseka kwengqondo okuguquguqukayo (imizwa eguquka isuke ekucindezelekeni iye ekuthokozeni okungavamile) noma imania noma uke wacabanga noma wazama ukuzibulala. Khuluma nodokotela wakho ngesimo sakho, izimpawu zakho, nomlando wakho wezempilo nowomndeni. Wena nodokotela wakho niyonquma ukuthi hlobo luni lwezokwelapha olulungele nina.

I-Lurasidone isetshenziselwa ukwelapha izimpawu ze-schizophrenia (ukugula kwengqondo okubangela ukuphazamiseka noma ukucabanga okungajwayelekile, ukuphelelwa yintshisekelo empilweni, kanye nemizwelo enamandla noma engafanele) kubantu abadala nezingane ezineminyaka engu-13 ubudala nangaphezulu. Ibuye isetshenziselwe ukwelapha ukudangala kubantu abadala kanye nezingane ezineminyaka eyi-10 nangaphezulu ezine-bipolar disorder (manic depress disorder; isifo esibangela iziqephu zokucindezeleka, iziqephu ze-mania, nezinye izimo ezingavamile). ILurasidone nayo iyasetshenziswa kanye ne-lithium (Lithobid) noma i-valproate (Depacon) yokwelapha ukudangala kubantu abadala abane-bipolar disorder. ILurasidone isekilasini lemithi ebizwa ngama-antipyychotic atypical. Isebenza ngokushintsha ukusebenza kwezinto ezithile zemvelo ebuchosheni.

ILurasidone iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa ngokudla (okungenani ama-calories angama-350) kanye ngosuku. Thatha i-lurasidone ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-lurasidone njengoba nje iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

ILurasidone ilawula i-schizophrenia nokudangala kubantu abane-bipolar disorder kepha ayizelaphi lezi zimo. Kungathatha amasonto ambalwa noma ngaphezulu ngaphambi kokuthi uzwe inzuzo ephelele ye-lurasidone. Qhubeka uthathe i-lurasidone noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-lurasidone ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-lurasidone,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-lurasidone, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-lurasidone. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• utshele udokotela wakho uma uthatha i-carbamazepine (Carbatrol, Epitol, Tegretol); i-clarithromycin (i-Biaxin, ku-Prevpac); ketoconazole; mibefradil; i-phenytoin (iDilantin, Phenytek); i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); i-ritonavir (i-Norvir); ISt John's wort; noma i-voriconazole (Vfend). Udokotela wakho uzokutshela ukuthi ungathathi i-lurasidone uma uthatha noma iyiphi yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: imishanguzo; ama-antihistamine; atazanavir (Reyataz); i-bosentan (iTracleer); i-diltiazem (Cardizem, Cartia, Taztia, Tiazac, nabanye); i-efavirenz (iSustiva, e-Atripla); i-erythromycin (E.E.S., E-Mycin, Ery-Tab, abanye); i-etravirine (Intelence); i-fluconazole (iDiflucan); indinavir (Crixivan); ipratropium (Atrovent, e-Combivent, eDuoneb); itraconazole (Sporanox); imithi yokulawula ukukhathazeka, ukuthambisa, amaphilisi okulala, noma ama-tranquilizers; imithi yokulawula umfutho wegazi; imithi ye-glaucoma, isifo sokuvuvukala kwamathumbu, isifo sokuhamba, i-myasthenia gravis, isifo sika-Parkinson, izilonda, noma izinkinga zomchamo; i-modafinil (i-Provigil); nafcillin; nefazodone; i-nelfinavir (i-Viracept); i-phenobarbital; i-pioglitazone (Actos, e-Duetact, e-Actoplus Met); i-rifabutin (i-Mycobutin); noma i-verapamil (Calan, Verelan, abanye, eTarka); Eminye imishanguzo ingaxhumana ne-lurasidone, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma usebenzisa noma wake wasebenzisa izidakamizwa zasemgwaqweni noma usebenzise ngokweqile imithi kadokotela futhi uma uke wahlaselwa isifo sohlangothi noma wake wahlaselwa isifo sohlangothi; i-ministroke (TIA); ubuhlungu besifuba, isifo senhliziyo, noma isifo senhliziyo; ukushaya kwenhliziyo okungajwayelekile; ukwehluleka kwenhliziyo; Isifo sikaParkinson (ukuphazamiseka kwesistimu yezinzwa okubangela ubunzima ngokunyakaza, ukulawula imisipha, nokulinganisela); Isifo i-Alzheimer's (isifo sobuchopho esonakalisa kancane inkumbulo namandla okucabanga, ukufunda, ukuxhumana nokuphatha imisebenzi yansuku zonke); ukuquleka; ukuwohloka komqondo; umdlavuza webele; unenkinga yokugcina ibhalansi yakho; noma isiphi isimo esenza kube nzima ukuthi usigwinye; umfutho wegazi ophakeme noma ophansi; amazinga aphezulu e-prolactin; izinga eliphezulu lamafutha (cholesterol kanye ne-triglycerides) egazini lakho; inani eliphansi lamaseli amhlophe egazi; isifo sezinso; isifo sesibindi; ushukela ophakeme wegazi; noma uma wena noma omunye emndenini wakho unesifo sikashukela noma owake waba naso. Tshela udokotela wakho uma uhlanza kakhulu noma uhudo noma izimpawu zokuphelelwa amandla emzimbeni manje, noma uma uba nalezi zimpawu noma kunini ngesikhathi sokwelashwa kwakho. Phinda utshele udokotela wakho uma wake wakuyeka ukuthatha umuthi wokugula ngengqondo ngenxa yemiphumela emibi kakhulu.
• Tshela udokotela wakho uma ukhulelwe, ikakhulukazi uma usezinyangeni ezimbalwa ezedlule zokukhulelwa kwakho, noma uma uhlela ukukhulelwa noma ukuncelisa. Uma ukhulelwa ngenkathi uthatha i-lurasidone, shayela udokotela wakho. ILurasidone ingadala izinkinga ezinganeni ezisanda kuzalwa ngemuva kokubeletha uma zithathwa ezinyangeni zokugcina zokukhulelwa.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-lurasidone.
• kufanele wazi ukuthi i-lurasidone ingakwenza ukozele. Ungashayeli imoto noma usebenzise imishini enobungozi uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi ungathola i-hyperglycemia (iyanda kushukela wakho wegazi) ngenkathi uthatha lo muthi, noma ngabe awunaso vele isifo sikashukela. Uma une-schizophrenia, kungenzeka ukuthi ube nesifo sikashukela kunabantu abangenayo i-schizophrenia, futhi ukuthatha i-lurasidone noma imishanguzo efanayo kungakhuphula le ngozi. Tshela udokotela wakho ngokushesha uma unezinye zalezi zimpawu ezilandelayo ngenkathi uthatha i-lurasidone: ukoma ngokweqile, ukuchama kaningi, ukulamba ngokweqile, ukungaboni kahle, noma ubuthakathaka. Kubaluleke kakhulu ukubiza udokotela wakho ngokushesha uma unezinye zalezi zimpawu, ngoba ushukela ophakeme wegazi ungadala isimo esibi esibizwa nge-ketoacidosis. I-Ketoacidosis ingasongela impilo uma ingelashwa kusenesikhathi. Izimpawu ze-ketoacidosis zifaka phakathi umlomo owomile, isicanucanu nokuhlanza, ukuphefumula okuncane, ukuphefumula okunuka izithelo, nokuncipha kokwazi.
• kufanele wazi ukuthi i-lurasidone ingadala isiyezi, ikhanda elikhanyayo, nokuquleka lapho uvuka masinyane usuka endaweni elele. Lokhu kuvame kakhulu lapho uqala ukuthatha i-lurasidone. Ukusiza ukugwema le nkinga, phuma embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
• kufanele wazi ukuthi i-lurasidone ingenza kube nzima ngomzimba wakho ukuphola lapho kushisa kakhulu. Tshela udokotela wakho uma uhlela ukuzivocavoca umzimba noma ukuvezwa ukushisa okukhulu.
• kufanele wazi ukuthi i-lurasidone ingadala ukwanda kwesisindo. Kubalulekile ukuthi uhlolwe isisindo sakho ngezikhathi ezithile ngenkathi uthatha lo muthi.

Ungadli inani elikhulu lamagilebhisi noma uphuze ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Thatha umthamo ophuthelwe ngokudla (okungenani ama-calories angama-350) ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

ILurasidone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isiyezi, ukuzizwa ungagxilile, noma unenkinga yokugcina ibhalansi yakho
• ukukhathazeka
• ubuthakathaka
• ukukhathala
• ukungahlaliseki
• ukuzamazama okungalawuleki kwengxenye yomzimba
• ukunyakaza okuhamba kancane noma ukushova ukuhamba
• isicanucanu
• ukuhlanza
• izinguquko zokudla
• ukwanda kwamathe
• ukukhulisa ibele noma ukukhipha
• isikhathi sokuya esikhathini sekwephuzile noma esilahlekile
• kwehle ikhono lezocansi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, noma lezo ezifakwe kuhlu KWEZIXWAYISO EZIBALULEKILE kanye NEZINYATHELO EZIKHETHEKILE, shayela udokotela wakho ngokushesha:

• isithuthwane
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• ubunzima bokugwinya noma ukuphefumula
• ukuphelelwa umoya
• ukushaya kwenhliziyo okungavamile
• umphimbo obuhlungu, umkhuhlane, ukukhwehlela, ukugodola nezinye izimpawu zokutheleleka
• umkhuhlane, ukujuluka, ukudideka, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, nokuqina kwemisipha okunzima
• ukunyakaza okungajwayelekile kobuso bakho noma komzimba ongeke ukwazi ukukulawula
• ukuwa

ILurasidone ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zebhu ukuze ahlole impendulo yomzimba wakho ku-lurasidone.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• ILatuda^®