Inaliti ye-Peginterferon Alfa-2b (Sylatron)

-Delile

• Ngaphambi kokujova umjovo we-peginterferon alfa-2b,
• Umjovo wePeginterferon alfa-2b ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

Umjovo wePeginterferon alfa-2b uyatholakala futhi njengomkhiqizo ohlukile (i-PEG-Intron) osetshenziselwa ukwelapha isifo sokusha kwesibindi kohlobo C (ukuvuvukala kwesibindi okubangelwa igciwane). Le monograph inikezela kuphela imininingwane ngomjovo we-peginterferon alfa-2b (Sylatron) osetshenziselwa ukunciphisa amathuba okuthi i-melanoma ebulalayo ibuye ngemuva kokuhlinzwa ukuyikhipha. Uma usebenzisa i-Peg-Intron, funda i-monograph enesihloko esithi Peginterferon alfa-2b (PEG-Intron) ukuze ufunde ngalo mkhiqizo.

Ukuthola umjovo we-peginterferon alfa-2b kungakhuphula ubungozi bokuthi uzoba nezinkinga zempilo yengqondo ebucayi noma esongela impilo, kufaka phakathi ukudangala okukhulu okungadala ukuthi ucabange, uhlele, noma uzame ukuzilimaza noma ukuzibulala; i-psychosis (ubunzima bokucabanga kahle, ukuqonda iqiniso, nokukhulumisana nokuziphatha ngendlela efanele); ne-encephalopathy (ukudideka, izinkinga zememori, nobunye ubunzima obudalwa ukusebenza kobuchopho okungavamile). Tshela udokotela wakho uma uke waba nenkinga yempilo yengqondo noma wake wacabanga ngokuzilimaza noma ukuzibulala. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: imizwa yokudabuka noma yokuphelelwa yithemba; ukucabanga, ukuhlela, noma ukuzama ukuzibulala noma ukuzilimaza; isimilo esinolaka; ukudideka; izinkinga zememori; ukuhlanya, injabulo engajwayelekile; noma ukubona izinto noma ukuzwa amazwi angekho. Qiniseka ukuthi umndeni wakho noma umnakekeli uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukufuna ukwelashwa uma ungakwazi ukuzibiza wedwa.

Gcina wonke ama-aphoyintimenti nodokotela wakho. Udokotela wakho mhlawumbe uzofuna ukukhuluma nawe ngempilo yakho yengqondo okungenani kanye njalo emavikini amathathu ekuqaleni kokwelashwa kwakho kanye kanye njalo ezinyangeni eziyisithupha njengoba ukwelashwa kwakho kuqhubeka. Udokotela wakho angakutshela ukuthi uyeke ukusebenzisa umjovo we-peginterferon alfa-2b uma uba nezimpawu zokugula kwengqondo. Kodwa-ke, uma uba nezinkinga zempilo yengqondo ngesikhathi sokwelashwa kwakho, lezi zinkinga kungenzeka zingapheli lapho uyeka ukuthola umuthi.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-peginterferon alfa-2b futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-peginterferon alfa-2b.

Umjovo wePeginterferon alfa-2b usetshenziswa kubantu abane-malignant melanoma (umdlavuza osongela impilo oqala kumaseli athile esikhumba) abahlinzwe ukukhipha umdlavuza. Lo muthi usetshenziselwa ukunciphisa amathuba okuthi i-melanoma ebulalayo izobuya futhi kufanele iqalwe zingakapheli izinsuku ezingama-84 zokuhlinzwa. Umjovo wePeginterferon alfa-2b usesigabeni semithi ebizwa ngama-interferon. Isebenza ngokumisa ukukhula kwamangqamuzana omdlavuza ukunciphisa amathuba okuthi ibuye i-melanoma ebulalayo.

Umjovo wePeginterferon alfa-2b uza njengempuphu yokuxubana noketshezi olunikeziwe bese ujova ngomgogodla (ngaphansi kwesikhumba). Imvamisa ijovwa kanye ngesonto kuze kube yiminyaka emihlanu. Jova umjovo we-peginterferon alfa-2b ngosuku olufanayo njalo ngesonto. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-peginterferon alfa-2b njengoba kuqondisiwe. Ungayifaki ngaphezulu noma ngaphansi kwayo noma uyijoje kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophakeme womjovo we-peginterferon alfa-2b futhi wehlise umthamo wakho ngemuva kwamasonto ayi-8. Udokotela wakho futhi anganciphisa umthamo wakho noma akutshele ukuthi uyeke ukusebenzisa umjovo we-peginterferon alfa-2b okwesikhashana noma unomphela uma uba nemiphumela emibi kakhulu.

Qhubeka nokusebenzisa umjovo we-peginterferon alfa-2b noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa umjovo we-peginterferon alfa-2b ngaphandle kokukhuluma nodokotela wakho.

Ungazijova nge-peginterferon alfa-2b ngokwakho noma umngani noma isihlobo abanikeze imijovo. Wena kanye nomuntu ozojova umuthi kufanele ufunde izinkomba zomkhiqizi zokuxuba nokujova umuthi ngaphambi kokuwusebenzisa okokuqala ekhaya. Cela udokotela wakho akubonise noma umuntu ozojova i-peginterferon alfa-2b ukuthi uyihlanganisa kanjani futhi uyijova.

I-Peginterferon alfa-2b iza ngekithi efaka imijovo edingekayo ukuxuba nokujova umuthi. Ungasebenzisi noma yiluphi olunye uhlobo lwesiponji ukuxuba noma ukujova umuthi wakho. Ungabelani noma usebenzise kabusha imijovo eza nomuthi wakho. Lahla izinaliti, imijovo, nezitsha ezitsheni ezingamelana nokubhoboza ngemuva kokuzisebenzisa kanye. Buza udokotela wakho noma usokhemisi ukuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Bheka isitsha se-peginterferon alfa-2b ngaphambi kokulungiselela umthamo wakho. Bheka ukuthi ibhalwe igama elifanele namandla emithi kanye nosuku lokuphelelwa yisikhathi okungazange kudlule. Imithi esesitsheni ingabukeka njengethebhulethi emhlophe noma emhlophe, noma ithebhulethi ingahle yephulwe yaba yizicucu noma impuphu. Uma ungenayo imishanguzo efanele, imithi yakho iphelelwe yisikhathi, noma ayibukeki ngendlela efanele, shayela usokhemisi wakho futhi ungayisebenzisi leyo vial.

Kufanele uxube kuphela isitsha esisodwa se-peginterferon alfa-2b ngasikhathi. Kungcono ukuxuba umuthi ngaphambi kokuhlela ukuwujova. Kodwa-ke, ungahlanganisa imishanguzo kusengaphambili, uyigcine esiqandisini, bese uyisebenzisa kungakapheli amahora angama-24. Uma udinga ukufaka esiqandisini imithi yakho, qiniseka ukuthi uyikhipha esiqandisini bese uyivumela ukuthi ifike ekamelweni lokushisa ngaphambi kokuyijova.

Ungafaka noma yikuphi emathangeni akho, ingaphandle langaphandle lezingalo zakho, noma isisu sakho ngaphandle kwendawo ezungeze ulwandle noma okhalweni lwakho. Uma uzacile kakhulu, akufanele ujove umuthi endaweni yesisu sakho. Khetha indawo entsha njalo lapho ufaka umuthi wakho. Musa ukujova kunoma iyiphi indawo ecasukile, ebomvu, elimele noma enesifo noma enezibazi, izigaxa noma amanwebu.

Ungase ube nezimpawu ezinjengomkhuhlane, imfiva, ukugodola, ubuhlungu bemisipha, ubuhlungu bamalunga, ukukhathala kanye nekhanda ngemuva kokujova umjovo we-peginterferon alfa-2b. Udokotela wakho uzokutshela ukuthi uthathe i-acetaminophen (Tylenol) imizuzu engama-30 ngaphambi kokujova umthamo wakho wokuqala futhi mhlawumbe ngaphambi kokujova imithamo yakho elandelayo yomjovo we-peginterferon alfa-2b. Ukujova umuthi wakho ngesikhathi sokulala kungasiza ekunciphiseni lezi zimpawu. Qiniseka ukuthi uphuza uketshezi oluningi uma uhlangabezana nezimpawu ezinjengomkhuhlane.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokujova umjovo we-peginterferon alfa-2b,

• Tshela udokotela wakho kanye nosokhemisi uma une-aleji kumjovo we-peginterferon alfa-2b (PegIntron, Sylatron), i-interferon alfa-2b (Intron), noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-peginterferon alfa-2b. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.Qiniseka ukuthi usho noma yikuphi okulandelayo: amitriptyline, aripiprazole (Abilify), celecoxib (Celebrex), clomipramine (Anafranil), codeine, desipramine (Norpramin), dextromethorphan (ngokukhwehlela nemithi ebandayo, eNuedexta), diclofenac (Cambia, Cataflam , Flector, Voltaren, abanye), duloxetine (Cymbalta), flecainide (Tambocor), fluvastatin (Lescol), glipizide (Glucotrol), haloperidol (Haldol), ibuprofen (Motrin), imipramine (Tofranil), irbesartan (Avapro), Cozaar), mexiletine, naproxen (Anaprox, Naprosyn), ondansetron (Zofran), paroxetine (Paxil, Pexeva), phenytoin (Dilantin), piroxicam (Feldene), propafenone (Rhythmol), risperidone (Risperdal), rosiganditazone (eBactrim, ngo-Septra), tamoxifen, thioridazine, timolol, tolbutamide, torsemide, tramadol (Conzip, Ultram, Ryzolt), venlafaxine (Effexor), ne-warfarin (Coumadin, Jantoven). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma ngabe uke waba nesifo sokusha kwesibindi noma sokuhlasela kwamasosha omzimba okuzenzakalelayo (isimo lapho amaseli omzimba ahlasela isibindi) noma ukulimala kwesibindi okubangelwa umuthi noma ukugula. Udokotela wakho angakutshela ukuthi ungasebenzisi umjovo we-peginterferon alfa-2b.
• Tshela udokotela wakho uma uke wasebenzisa izidakamizwa zasemgwaqweni noma imishanguzo kadokotela esetshenziswe ngokweqile futhi uma uke waba ne-retinopathy (ukonakala kwamehlo okubangelwa yisifo sikashukela noma ezinye izimo), isifo sikashukela, noma isifo segilo.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha umjovo we-peginterferon alfa-2b, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Buza udokotela wakho ukuthi yini okufanele uyenze uma uphuthelwa umthamo. Musa ukujova umthamo ophindwe kabili ukwenzela okulahlekile.

Umjovo wePeginterferon alfa-2b ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isiyezi
• isifo sohudo
• isicanucanu
• ukuhlanza
• izinkinga ngokunambitha noma ukuhogela
• ukulahlekelwa isifiso sokudla
• ukuba ndikindiki, ukushiswa, noma ukuncinza kwezingalo, izandla, imilenze noma izinyawo
• ukukhwehlela
• ukuqubuka
• ukulahleka kwezinwele

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• ubuhlungu besifuba
• ukuphefumula kanzima
• ukuphuzi kwesikhumba noma kwamehlo
• ukuvuvukala kwesisu
• ubunzima bokugxila
• ukuzwa kubanda noma kushisa ngaso sonke isikhathi
• ukuzuza kwesisindo noma ukwehla
• ukoma okwandisiwe
• ukwanda kokuchama
• umoya othelayo
• ukuncipha noma ukufiphala kwamehlo

Umjovo wePeginterferon alfa-2b ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina imishanguzo engaxutshiwe yemithi ekamelweni lokushisa kanye nokushisa okuthe xaxa nomswakama (hhayi endlini yangasese). Gcina imithi exutshwe esiqandisini bese uyisebenzisa kungakapheli amahora angama-24. Ungavumeli ukuthi umuthi ubanda.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukukhathala ngokweqile
• ikhanda
• ubuhlungu bemisipha
• umphimbo obuhlungu, umkhuhlane, amakhaza nezinye izimpawu zokutheleleka
• ukulimaza noma ukopha okungavamile

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Sylatron^®