U-Elbasvir noGrazoprevir

-Delile

• Ngaphambi kokuthatha i-elbasvir ne-grazoprevir,
• I-Elbasvir ne-grazoprevir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha:

Kungenzeka ukuthi usungenwe yi-hepatitis B (igciwane elithelela isibindi futhi lingadala ukulimala kwesibindi) kepha ungabi nazimpawu zesifo. Kulokhu, ukuthatha inhlanganisela ye-elbasvir ne-grazoprevir kungandisa ubungozi bokuthi ukutheleleka kwakho kuzoba kubi kakhulu noma kusongele impilo futhi uzoba nezimpawu. Tshela udokotela wakho uma ngabe uke waba nokutheleleka ngegciwane le-hepatitis B. Udokotela wakho uzokuyalela ukuhlolwa kwegazi ukuze abone ukuthi uke waba nokutheleleka kwesifo sikashukela B. Udokotela wakho uzokuhlola futhi nangezimpawu zokutheleleka kwesifo sokusha kwesibindi kohlobo B ngesikhathi nangezinyanga ezimbalwa ngemuva kokwelashwa kwakho. Uma kunesidingo, udokotela wakho angakunika imithi yokwelapha lesi sifo ngaphambi nangesikhathi sokwelashwa kwakho ngokuhlanganiswa kwe-elbasvir ne-grazoprevir. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva kokwelashwa kwakho, shayela udokotela wakho ngokushesha: ukukhathala ngokweqile; ukuphuzi kwesikhumba noma kwamehlo; ukulahlekelwa ukudla; isicanucanu noma ukuhlanza; indle ephaphathekile; ubuhlungu ohlangothini olungaphezulu kwesokudla sendawo yesisu; noma umchamo omnyama.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile ngaphambi, ngesikhathi, nangemva kokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ekuhlanganisweni kwe-elbasvir ne-grazoprevir.

Khuluma nodokotela wakho ngobungozi (s) bokuthatha inhlanganisela ye-elbasvir ne-grazoprevir.

Inhlanganisela ye-elbasvir ne-grazoprevir isetshenziswa yodwa noma ihlanganiswe ne-ribavirin (i-Copegus, i-Rebetol, i-Ribasphere, i-Virazole) ukwelapha uhlobo oluthile lokutheleleka okungapheli (kwesikhathi eside) kwesifo sokusha kwesibindi kohlobo C (ukuvuvukala kwesibindi okubangelwa igciwane). U-Elbasvir usesigabeni semithi elwa namagciwane ebizwa nge-HCV NS5A inhibitors. Isebenza ngokuvimba igciwane elibangela ukusha kwesibindi kohlobo C ekusakazekeni ngaphakathi komzimba. I-Grazoprevir isekilasini lemithi ebizwa nge-protease inhibitors. Isebenza ngokunciphisa inani le-virus ye-hepatitis C (HCV) emzimbeni. Akwaziwa ukuthi i-elbasvir ne-grazoprevir zivimbela ukusakazeka kwesifo sokusha kwesibindi kohlobo C kwabanye abantu.

Inhlanganisela ye-elbasvir ne-grazoprevir iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa nokudla noma ngaphandle kokudla kanye nsuku zonke amasonto ayi-12 kuya kwayi-16. Thatha i-elbasvir ne-grazoprevir ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-elbasvir ne-grazoprevir njengoba nje kuyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Qhubeka uthathe i-elbasvir ne-grazoprevir noma ngabe uzizwa uphilile. Ubude bokwelashwa kwakho buxhomeke esimeni sakho, ukuthi uphendula kahle kanjani emithini, nokuthi ngabe unemiphumela emibi kakhulu yini. Ungayeki ukuthatha i-elbasvir ne-grazoprevir ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-elbasvir ne-grazoprevir,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-elbasvir, grazoprevir, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-elbasvir kanye ne-grazoprevir. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-atazanavir (Reyataz), carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), cyclosporine (Gengraf, Neoral, Sandimmune), darunavir (Prezista, e Prezcobix), efavirenz (Sustiva, in Atripla), lopina eKaletra), phenytoin (Dilantin, Phenytek), rifampin (Rifadin, Rimactane, eRifamate, eRifater), saquinavir (Invirase), iSt John's wort, noma tipranavir (Aptivus). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-elbasvir ne-grazoprevir uma uthatha eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: bosentan (Tracleer); i-cobicistat ethathwe kanye ne-elvitegravir, emtricitabine, ne-tenofovir (Genvoya, Stribild); i-etravirine (Intelence); imithi yokwelapha i-cholesterol ephezulu njenge-atorvastatin (Lipitor, eCaduet), i-fluvastatin (Lescol XL), i-lovastatin (i-Altoprev), i-rosuvastatin (i-Crestor), ne-simvastatin (i-Zocor, e-Vytorin); ketoconazole; i-modafinil (i-Provigil); nafcillin; i-tacrolimus (Astagraf, Envarsus, Prograf, nabanye); kanye ne-warfarin (Coumadin, Jantoven). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-elbasvir ne-grazoprevir, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo lwesifo sesibindi ngaphandle kwesifo sokusha kwesibindi kohlobo C. Udokotela wakho angakutshela ukuthi ungathathi i-elbasvir ne-grazoprevir.
• utshele udokotela wakho uma uke walinda noma ulinde ukufakelwa isibindi noma uma unegciwane lengculazi (i-HIV).
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-elbasvir ne-grazoprevir, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Elbasvir ne-grazoprevir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ikhanda
• ubunzima bokulala noma ukulala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha:

• ubuthongo
• ukudideka
• ukuvuvukala kwendawo yesisu
• ukuhlanza igazi noma okokusebenza okubukeka njengezizathu zekhofi
• indle emnyama, emnyama, noma enegazi

I-Elbasvir ne-grazoprevir kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungawasusi amaphilisi emaphaketheni kuze kube ngaphambi kokuwasebenzisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi.Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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