I-Efavirenz, i-Emtricitabine, ne-Tenofovir

-Delile

• Ngaphambi kokuthatha i-efavirenz, i-emtricitabine, ne-tenofovir,
• I-Efavirenz, emtricitabine, ne-tenofovir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Efavirenz, emtricitabine, ne-tenofovir akumele isetshenziselwe ukwelapha ukutheleleka ngegciwane le-hepatitis B (HBV; ukutheleleka kwesibindi okuqhubekayo). Tshela udokotela wakho uma unayo noma ucabanga ukuthi ungaba ne-HBV. Udokotela wakho angakuhlola ukuthi unayo yini i-HBV ngaphambi kokuba uqale ukwelashwa kwakho nge-efavirenz, emtricitabine, ne-tenofovir. Uma une-HBV futhi uthatha i-efavirenz, emtricitabine, ne-tenofovir, isimo sakho singase sibe sibi ngokungazelelwe lapho uyeka ukuthatha lo muthi. Udokotela wakho uzokuhlola futhi a-oda izivivinyo zebhu njalo ezinyangeni ezimbalwa ngemuva kokuyeka ukuthatha lo muthi ukubona ukuthi i-HBV yakho isiba kubi kakhulu.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-efavirenz, emtricitabine, naku-tenofovir.

Khuluma nodokotela wakho ngobungozi bokuthatha i-efavirenz, i-emtricitabine, ne-tenofovir.

Inhlanganisela ye-efavirenz, emtricitabine, ne-tenofovir isetshenziswa yodwa noma kanye neminye imithi yokwelapha ukutheleleka ngegciwane lesandulela ngculazi (HIV) kubantu abadala nasezinganeni ezinesisindo esingaphezu kwama-40 kg (88 lb). I-Efavirenz ikwisigaba semithi engeyona i-nucleoside reverse transcriptase inhibitors (NNRTIs). I-Emtricitabine ne-tenofovir basesigabeni semithi ebizwa nge-nucleoside reverse transcriptase inhibitors (NRTIs). Basebenza ngokunciphisa inani le-HIV emzimbeni. Yize i-efavirenz, i-emtricitabine, ne-tenofovir kungeke kuyelaphe i-HIV, le mithi inganciphisa amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezifana nezifo ezinqala noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko kwimpilo yakho kunganciphisa ubungozi bokuthola noma ukudlulisela igciwane le-HIV kwabanye abantu.

Inhlanganisela ye-efavirenz, i-emtricitabine, ne-tenofovir iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku ngamanzi esiswini esingenalutho (okungenani ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla). Thatha i-efavirenz, emtricitabine, ne-tenofovir ngasikhathi sinye nsuku zonke. Ukuthatha i-efavirenz emtricitabine, ne-tenofovir ngesikhathi sokulala kungenza imiphumela ethile engemihle ingakhathazi kangako. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-efavirenz, i-emtricitabine, ne-tenofovir njengoba nje kuyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Qhubeka nokudla i-efavirenz, emtricitabine, ne-tenofovir noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-efavirenz, i-emtricitabine, ne-tenofovir ngaphandle kokukhuluma nodokotela wakho. Uma uyeka ukuthatha i-efavirenz, i-emtricitabine, ne-tenofovir ngisho noma isikhashana, noma weqa imithamo, igciwane lingazwela emithini futhi kungaba nzima ukuselapha.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-efavirenz, i-emtricitabine, ne-tenofovir,

• Tshela udokotela kanye nosokhemisi wakho uma uxabana ne-efavirenz, emtricitabine, noma i-tenofovir, noma imuphi omunye umuthi, noma iziphi izithako ze-efavirenz, emtricitabine, kanye namaphilisi e-tenofovir. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-voriconazole (Vfend) noma i-elbasvir ne-grazoprevir (iZepatier). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-efavirenz, i-emtricitabine, ne-tenofovir uma uthatha owodwa noma ngaphezulu wale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunomsoco, okwenzayo noma ohlela ukukuthatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: acyclovir (Sitavig, Zovirax); i-adefovir (Hepsera); imishanguzo; i-artemether ne-lumefantrine (Coartem); atazanavir (Reyataz); i-atorvastatin (Lipitor, eCaduet); i-atovaquone ne-proguanil (Malarone); i-boceprevir (i-Victrelis); i-bupropion (Wellbutrin, iZyban, abanye); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); i-clarithromycin (i-Biaxin, ku-Prevpac); cidofovir; i-cyclosporine (Gengraf, Neoral, Sandimmune); i-darunavir (i-Prezista) ne-ritonavir (i-Norvir); i-delavirdine (i-Rescriptor); i-didanosine (i-Videx); i-diltiazem (iCardizem, iCartia, iDiltzac, iTaztia, iTiazac); i-ethinyl estradiol ne-norgestimate (Estarylla, Ortho-Tri-Cyclen, Sprintec, abanye); i-etonogestrel (Nexplanon, eNuvaring); i-etravirine (Intelence); felodipine; i-fosamprenavir (Lexiva); i-ganciclovir (i-cytovene); i-gentamicin; i-glecaprevir ne-pibrentasvir (iMavyret); indinavir (Crixivan); itraconazole (Onmel, Sporanox); ketoconazole; lamivudine (Epivir, Epivir HBV, kuCombivir, Epzicom, Triumeq, Trizivir); i-ledipasvir ne-sofosbuvir (Harvoni); i-lopinavir ne-ritonavir (Kaletra); i-maraviroc (i-Selzentry); imithi yokukhathazeka, ukugula kwengqondo, nokuhlaselwa; i-methadone (i-Dolophine, i-Methadose); i-nevirapine (i-Viramune); i-nicardipine (Cardene); i-nifedipine (i-Adalat, i-Afeditab, iProcardia); i-phenobarbital; i-phenytoin (iDilantin, Phenytek); imishanguzo yokulwa nokuvuvukala (ama-NSAID) anjenge-celecoxib (Celebrex), ibuprofen (Advil, Motrin), meloxicam (Mobic), ne-naproxen (Aleve, Naprelan, Naprosyn); eminye imishanguzo ye-HIV equkethe i-efavirenz, emtricitabine, ne-tenofovir (Complera, Descovy, Genvoya, Odefsey, Stribild, Truvada, Sustiva, Emtriva, Viread); i-posaconazole (Noxafil); i-pravastatin (Pravachol); i-raltegravir (i-Isentress); i-rifabutin (i-Mycobutin); i-rifampin (i-Rifadin, i-Rimactane, e-Rifamate, i-Rifater); i-ritonavir (iNorvir, eKaletra, Technivie, eViekira Pak); i-saquinavir (i-Invirase); isidambisi; i-sertraline (iZoloft); amaphilisi okulala; simeprevir (Olysio); simvastatin (iZocor, eVytorin); i-sirolimus (i-Rapamune); i-sofosbuvir ne-velpatasvir (i-Epclusa); i-sofosbuvir, i-velpatasvir, ne-voxilaprevir (i-Vosevi); tacrolimus (Astagraf, Envarsus, Prograf); okokunciphisa umzimba; i-valacyclovir (iValtrex); i-valganciclovir (iValcyte); i-verapamil (Calan, Covera, Tarka, Verelan); kanye ne-warfarin (Coumadin, Jantoven). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-efavirenz, emtricitabine, ne-tenofovir, noma ingakhuphula ubungozi bokuthi uzohlaselwa ukulimala kwesibindi ngesikhathi ukwelashwa kwakho nge-efavirenz, emtricitabine, ne-tenofovir, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo. , ngisho nalezo ezingabonakali kulolu hlu.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• Tshela udokotela wakho ukuthi njengamanje noma unesikhathi eside se-QT (inkinga yenhliziyo engajwayelekile engadala ukushaya kwenhliziyo okungajwayelekile, ukuquleka, noma ukufa okungazelelwe), noma amazinga aphansi we-potassium noma i-magnesium egazini lakho, owake waphuza utshwala obuningi, wasebenzisa izidakamizwa zomgwaqo , noma imishanguzo kadokotela esetshenziswe ngokweqile. Phinda utshele udokotela wakho uma uke waba nanoma yiziphi izimo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, ukudangala noma okunye ukugula ngengqondo, izinkinga zamathambo kubandakanya i-osteoporosis (isimo lapho amathambo eba mancane futhi abe buthakathaka futhi aphuke kalula) noma ukuphuka kwamathambo , ukuquleka, noma isifo sesibindi noma sezinso.
• utshele udokotela wakho uma ukhulelwe, noma uhlele ukukhulelwa.Akufanele ukhulelwe ngesikhathi sokwelashwa kwakho namasonto ayi-12 ngemuva komthamo wakho wokugcina. Uma ungakhulelwa, kuzofanele ube nokuhlolwa kokukhulelwa okungekuhle ngaphambi kokuthi uqale ukusebenzisa le mithi futhi usebenzise ukulawulwa kokubeletha okusebenzayo ngesikhathi sokwelashwa kwakho. I-Efavirenz, i-emtricitabine, ne-tenofovir kungaphazamisa ukusebenza kwemithi yokuvimbela inzalo yamahomoni (amaphilisi okulawula ukubeletha, amabala, izindandatho, okufakelwa, noma imijovo), ngakho-ke akufanele usebenzise lokhu njengendlela yakho kuphela yokulawula ukubeletha ngesikhathi sokwelashwa kwakho. Kufanele usebenzise indlela yokuvimbela inzalo (idivaysi evimba isidoda ukuthi singene esibelethweni njengekhondomu noma idayaphragm) kanye nanoma iyiphi enye indlela yokulawula ukubeletha oyikhethile. Buza udokotela wakho ukuthi akusize ukhethe indlela yokulawula ukubeletha ezokusebenzela. Uma ukhulelwa ngenkathi uthatha i-efavirenz, i-emtricitabine, ne-tenofovir, shayela udokotela wakho ngokushesha.
• akufanele uncelise ibele uma utheleleke nge-HIV noma uthatha i-efavirenz, i-emtricitabine, ne-tenofovir.
• kufanele wazi ukuthi amafutha omzimba wakho angakhuphuka noma ahambele ezindaweni ezahlukahlukene zomzimba wakho, njengasemhlane wakho ongaphezulu, entanyeni (’’ inyathi ’), amabele, nasesizungeze isisu sakho. Ungaqaphela ukulahleka kwamafutha omzimba ebusweni bakho, emilenzeni nasezingalweni.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho noma zidale ukuthi ezinye izimo zivele. Lokhu kungadala ukuthi uthuthukise izimpawu zalezo zifo noma izimo. Uma unezimpawu ezintsha noma eziya ziba zimbi phakathi nokwelashwa kwakho nge-efavirenz, emtricitabine, ne-tenofovir qiniseka ukutshela udokotela wakho.
• kufanele wazi ukuthi i-efavirenz, i-emtricitabine, ne-tenofovir kungakwenza ukozele, ube nesiyezi, noma ungakwazi ukugxilisa ingqondo. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi i-efavirenz, emtricitabine, ne-tenofovir kungadala ushintsho emicabangweni yakho, ekuziphatheni, noma empilweni yengqondo. Shayela udokotela wakho masisha uma uba nezimpawu ezilandelayo ngenkathi uthatha i-efavirenz: ukudangala, ukucabanga ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo, ukuziphatha okuthukuthele noma okunolaka, ukubona izinto ezingekho (ukubona izinto noma ukuzwa amazwi angekho), imicabango engajwayelekile, noma ukulahlekelwa ukuthintana neqiniso. Qiniseka ukuthi umndeni wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukushayela udokotela wakho uma ungakwazi ukufuna ukwelashwa wedwa.
• buza udokotela wakho mayelana nokusetshenziswa okuphephile kophuzo oludakayo ngenkathi uthatha i-efavirenz, emtricitabine, ne-tenofovir. Utshwala bungenza imiphumela emibi ye-efavirenz, emtricitabine, ne-tenofovir ibe yimbi kakhulu.
• kufanele wazi ukuthi i-efavirenz ingadala izinkinga zesistimu ezingaba yingozi, kufaka phakathi i-encephalopathy (isifo esibi futhi esingaba yingozi ebuchosheni) ezinyangeni noma eminyakeni ngemuva kokuqala ukuthatha i-efavirenz, emtricitabine, ne-tenofovir. Yize izinkinga zesistimu yezinzwa zingase ziqale ngemuva kokuthatha i-efavirenz, i-emtricitabine, ne-tenofovir isikhathi esithile, kubalulekile ukuthi wena nodokotela wakho nazi ukuthi zingabangelwa yi-efavirenz. Shayela udokotela wakho ngokushesha uma uhlangabezana nezinkinga ngebhalansi nokuxhumanisa, ukudideka, izinkinga zememori, nobunye ubunzima obubangelwa ukusebenza kobuchopho okungavamile, nganoma yisiphi isikhathi lapho welashwa nge-efavirenz, emtricitabine, ne-tenofovir. Udokotela wakho angakutshela ukuthi uyeke ukuthatha i-efavirenz, i-emtricitabine, ne-tenofovir.

Khuluma nodokotela wakho ngokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Efavirenz, emtricitabine, ne-tenofovir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isifo sohudo
• igesi
• ukugaya ukudla
• mnyama kombala wesikhumba, ikakhulukazi ezintendeni zezandla noma ematheni ezinyawo
• isikhumba esiphaphathekile
• ubunzima bokulala noma ukulala
• ukudideka
• ukukhohlwa
• ukuzizwa uthukuthele, ukhathazekile noma wethukile
• imizwa ejabule ngokungavamile
• amaphupho angajwayelekile
• ubuhlungu obuhlangene noma obuya emuva
• ukulunywa

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuncipha kokuchama
• uchama amanani amakhulu
• ukoma okwandisiwe
• ubuhlungu obuqhubekayo noma obukhulayo bethambo
• ukuphuka kwamathambo
• ubuhlungu ezandleni, ezandleni, ezinyaweni noma emilenzeni
• ubuhlungu bemisipha noma ubuthakathaka
• ukuqubuka
• ukuxebuka, ukushwabana, noma ukuchitha isikhumba
• ukuba ndikindiki, ukushiswa, noma ukuncinza ezandleni, ezingalweni, ezinyaweni noma emilenzeni
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, imilenze, amaqakala noma izinyawo
• ubunzima bokugwinya noma ukuphefumula
• ukushaqeka
• isithuthwane
• izimpawu ezinjengomkhuhlane
• isicanucanu
• ukuhlanza
• ukukhathala ngokweqile
• ukuphuzi kwesikhumba noma kwamehlo; ukunyakaza kwamathumbu okukhanyayo; umchamo omnyama ophuzi noma onsundu; ukulahlekelwa ukudla; ubuhlungu engxenyeni engaphezulu kwesokudla sesisu; ukopha okungavamile noma ukulinyazwa
• ubuthakathaka; ubuhlungu bemisipha; ukuphefumula okuncane noma ukuphefumula okusheshayo; ubuhlungu besisu ngokuhlanza nokuhlanza; izandla nezinyawo ezibandayo noma eziluhlaza okwesibhakabhaka; ukuzizwa unesiyezi noma ikhanda elincane; noma ukushaya kwenhliziyo okusheshayo noma okungajwayelekile

I-Efavirenz, emtricitabine, ne-tenofovir kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukunyakaza komzimba wakho ongeke ukwazi ukukulawula
• isiyezi
• ubunzima bokugxila
• uvalo
• ukudideka
• ukukhohlwa
• ubunzima bokulala noma ukulala
• amaphupho angajwayelekile
• ukozela
• ukusangana (ukubona izinto noma ukuzwa amazwi angekho)
• imizwa ejabule ngokungavamile
• imicabango engajwayelekile

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi uthatha i-efavirenz, i-emtricitabine, ne-tenofovir.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Gcina i-efavirenz, i-emtricitabine ne-tenofovir zikhona. Ungalindi uze uphelelwe yimithi yokugcwalisa imishanguzo yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Atripla^® (njengomkhiqizo ohlanganisiwe oqukethe i-Efavirenz, i-Emtricitabine, i-Tenofovir)