Semaglutide

-Delile

• Ngaphambi kokuthatha i-semaglutide,
• Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.
• I-Semaglutide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Semaglutide ingakhuphula ubungozi bokuthi uzoba nezicubu zomgudu wegilo, kufaka phakathi i-medullary thyroid carcinoma (MTC; uhlobo lomdlavuza wegilo). Izilwane zaselabhorethri ezinikezwe ama-semaglutide zaba nezimila, kepha akwaziwa ukuthi lo muthi wandisa ingozi yezimila kubantu. Tshela udokotela wakho ukuthi ngabe wena noma omunye emndenini wakho une-MTC noma i-Multiple Endocrine Neoplasia syndrome type 2 (MEN 2; isimo esidala izicubu ezingxenyeni ezingaphezu kweyodwa emzimbeni). Uma kunjalo, udokotela wakho uzokutshela ukuthi ungathathi i-semaglutide. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isigaxa noma ukuvuvukala entanyeni, ukushuba, ubunzima bokugwinya, noma ukuphefumula okuncane.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-semaglutide.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngamaphilisi e-semaglutide futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokuthatha i-semaglutide.

I-Semaglutide isetshenziswa kanye nohlelo lokudla nokuzivocavoca ukulawula amazinga kashukela kubantu abadala abanesifo sikashukela sohlobo lwesibili (isimo lapho umzimba ungasebenzisi khona i-insulin ngokujwayelekile ngakho-ke awukwazi ukulawula inani likashukela egazini) lapho eminye imithi ingalawuleki amazinga kashukela ngokwanele. I-Semaglutide ayisetshenziselwa ukwelapha isifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi i-insulin ngakho-ke awukwazi ukulawula inani likashukela egazini) noma i-ketoacidosis yesifo sikashukela (isimo esibi esingakhula uma ushukela wegazi ongelashwa). I-Semaglutide isekilasini lemithi ebizwa nge-incretin mimetics. Isebenza ngokusiza ama-pancreas ukukhipha inani elifanele le-insulin lapho amazinga kashukela egazi ephezulu. I-insulin isiza ukuhambisa ushukela egazini uye kwezinye izicubu zomzimba lapho usetshenziselwa khona amandla. I-Semaglutide nayo isebenza ngokunciphisa ukuhamba kokudla esiswini.

Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukusebenzisa imithi, ukwenza izinguquko endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela futhi kuthuthukise impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

I-Semaglutide iza njengethebhulethi ukuthatha ngomlomo. Imvamisa iphuzwa esiswini esingenalutho kanye ngosuku lapho uvuka. Thatha i-semaglutide ngesiphuzo samanzi (esingekho ngaphezu kwama-ounces ayi-120) okungenani imizuzu engama-30 ngaphambi kokudla isidlo noma isidlo, uphuze noma uthathe noma imuphi omunye umuthi. Isidakamizwa sisebenza kahle kakhulu uma udla isidlo noma isinongo imizuzu engama-30 kuye kwangama-60 ngemuva kokuthatha umuthi. Udokotela wakho angakhuphula kancane umthamo wakho, kuya ngempendulo yakho ku-semaglutide. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-semaglutide njengoba nje kuqondisiwe. Ungayithathi ngaphezulu noma ngaphansi kwayo noma uyithathe kaningi kunokuqondiswa ilebula lephakeji noma unikezwe ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

I-Semaglutide ilawula isifo sikashukela kepha ayiselaphi. Qhubeka uthathe i-semaglutide noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-semaglutide ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-semaglutide,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergies ku-semaglutide (i-Ozempic, i-Rybelsus), i-alibiglutide (iTanzeum; ayisatholakali e-US); i-dulaglutide (i-Trulicity), i-exenatide (i-Bydureon, i-Byetta), i-liraglutide (i-Saxenda, i-Victoza, e-Xultophy), i-lixisenatide (i-Adlyxin, e-Soliqua), noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-semaglutide. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyiphuzayo ngomlomo ngoba i-semaglutide ingashintsha indlela umzimba wakho oyithatha ngayo le mithi. Futhi qiniseka ukuthi usho i-insulin, i-levothyroxine (i-Euthyrox, i-Levo-T, i-Levoxyl, i-Synthroid, i-Tirosint, abanye), i-sulfonylureas efana ne-glimepiride (i-Amaryl, e-Duetact), i-glipizide (i-Glucotrol), i-glyburide (i-DiaBeta, i-Glynase), i-tolazamide, ne-tolazamide tolbutamide. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba ne-pancreatitis (ukuvuvukala kwamanyikwe), isifo sikashukela sokuphindaphinda (ukulimala kwamehlo okubangelwa yisifo sikashukela), noma isifo sezinso. Phinda utshele udokotela wakho uma usanda kuba nohudo, isicanucanu, noma ukuhlanza noma uma ungakwazi ukuphuza uketshezi ngomlomo, okungadala ukoma (ukulahlekelwa inani elikhulu lamanzi omzimba).
• tshela udokotela wakho uma uhlela ukukhulelwa. Udokotela wakho angakutshela ukuthi uyeke ukuthatha i-semaglutide izinyanga ezimbili ngaphambi kokukhulelwa okuhleliwe.
• utshele udokotela wakho uma ukhulelwe, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-semaglutide, shayela udokotela wakho.
• Uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-semaglutide.
• buza udokotela wakho ukuthi wenzeni uma kunoshintsho olukhulu ekudleni kwakho, ekuzivocavoca umzimba, noma esisindweni; noma uma ugula, uba nesifo noma umkhuhlane, ube nengcindezi engajwayelekile, noma ulimale. Lezi zinguquko nezimo zingathinta ushukela wegazi lakho kanye nenani le-semaglutide ongayidinga.

Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo. Kubalulekile ukudla ukudla okunempilo, ukuzivocavoca umzimba njalo, nokunciphisa isisindo uma kunesidingo. Lokhu kuzosiza ukulawula isifo sakho sikashukela futhi kusize i-semaglutide isebenze kahle.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.

I-Semaglutide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ubuhlungu besisu
• ukuqunjelwa
• ukuncipha kokudla
• isilungulela
• ukubhoboza

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu obuqhubekayo obuqala ngaphezulu kwesobunxele noma maphakathi nesisu kepha bungasabalala buye emhlane, ngokuhlanza noma ngaphandle kokuhlanza
• ukuqubuka; ukulunywa; ukuvuvukala kwamehlo, ubuso, umlomo, ulimi, noma umphimbo; ukuphefumula kanzima noma ukugwinya
• ukuncipha kokuchama; ukuvuvukala kwemilenze, amaqakala, noma izinyawo
• umbono uyashintsha

I-Semaglutide ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Ushukela wegazi kanye ne-hemoglobin eglycosylated (HbA1c) kufanele ihlolwe njalo ukuthola impendulo yakho ku-semaglutide. Udokotela wakho uzokutshela nokuthi ungayihlola kanjani impendulo yakho kulo muthi ngokulinganisa amazinga kashukela egazini lakho ekhaya. Landela le miyalo ngokucophelela.

Kufanele njalo ufake isongo lokuhlonza isifo sikashukela ukuze uqiniseke ukuthi uthola ukwelashwa okufanele esimeni esiphuthumayo.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UReybelsus^®