ICyclophosphamide

-Delile

• Ngaphambi kokuthatha i-cyclophosphamide,
• I-Cyclophosphamide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Cyclophosphamide isetshenziswa yodwa noma ihlanganiswe neminye imithi yokwelapha i-Hodgkin's lymphoma (isifo sikaHodgkin) kanye ne-non-Hodgkin's lymphoma (izinhlobo zomdlavuza eziqala ngohlobo lwamaseli amhlophe egazi ngokuvamile alwa nokutheleleka); i-T-cell lymphoma enqamulelayo (i-CTCL, iqembu lomdlavuza wamasosha omzimba aqala ukuvela njengokuqubuka kwesikhumba); i-myeloma eminingi (uhlobo lomdlavuza womnkantsha wethambo); nezinhlobo ezithile ze-leukemia (umdlavuza wamangqamuzana amhlophe egazi), kufaka phakathi i-lymphocytic leukemia (CLL) engapheli, i-leukemia engapheli (i-CML), i-acute myeloid leukemia (AML, ANLL), ne-acute lymphoblastic leukemia (ALL). Ibuye isetshenziselwe ukwelapha i-retinoblastoma (umdlavuza esweni), i-neuroblastoma (umdlavuza oqala kumaseli ezinzwa futhi uvele ikakhulukazi ezinganeni), umdlavuza wesibeletho (umdlavuza oqala ezithweni zokuzala zabesifazane lapho kwakhiwa khona amaqanda), nomdlavuza webele . I-Cyclophosphamide nayo isetshenziselwa ukwelapha i-nephrotic syndrome (isifo esidalwa ukulimala kwezinso) ezinganeni isifo esingakathuthuki, sesibe sibi kakhulu, noma sibuyele emuva kokuthatha eminye imishanguzo noma ezinganeni ezihlangabezane nemiphumela emibi engabekezeleleki nezinye imithi. I-Cyclophosphamide isekilasini lemithi ebizwa ngama-alkylating agents. Lapho i-cyclophosphamide isetshenziselwa ukwelapha umdlavuza, isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho. Lapho i-cyclophosphamide isetshenziselwa ukwelapha i-nephrotic syndrome, isebenza ngokucindezela amasosha omzimba wakho.

I-Cyclophosphamide iza njengethebhulethi yokuphuza ngomlomo kanye ngosuku. Ubude bokwelashwa buxhomeke ezinhlotsheni zemithi oyiphuzayo, ukuthi umzimba wakho uphendula kahle kangakanani kuyo, nohlobo lomdlavuza noma isimo onaso. Thatha i-cyclophosphamide ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-cyclophosphamide njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma alungise umthamo wakho we-cyclophosphamide ngokuya ngempendulo yakho ekwelashweni nanoma yimiphi imiphumela emibi ohlangabezana nayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho. Ungayeki ukuthatha i-cyclophosphamide ngaphandle kokukhuluma nodokotela wakho.

ICyclophosphamide kwesinye isikhathi isetshenziselwa ukwelapha uhlobo oluthile lomdlavuza wamaphaphu (umdlavuza omncane wamaphaphu wamangqamuzana; i-SCLC). Ibuye isetshenziselwe ukwelapha i-rhabdomyosarcoma (uhlobo lomdlavuza wemisipha) ne-Ewing's sarcoma (uhlobo lomdlavuza wamathambo) ezinganeni. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-cyclophosphamide,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-cyclophosphamide, amanye ama-alkylating agents afana ne-bendamustine (iTreanda^®), busulfan (Myerlan^®, Busulfex^®), i-carmustine (BiCNU^®, Gliadel^® I-Wafer), i-chlorambucil (iLeukeran^®), ifosfamide (Ifex^®), lomustine (CeeNU^®), I-melphalan (Alkeran^®), procarbazine (Mutalane^®), noma i-temozolomide (Temodar^®), noma imuphi omunye umuthi, noma iziphi izithako kumaphilisi e-cyclophosphamide. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: allopurinol (Zyloprim^®), i-cortisone acetate, i-doxorubicin (i-Adriamycin^®, Doxil^®), i-hydrocortisone (iCortef^®), noma i-phenobarbital (Luminal^® Isodium). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-cyclophosphamide, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• utshele udokotela wakho ukuthi wake wathola ukwelashwa ngeminye imithi yokwelapha ngamakhemikhali noma uma usanda kuthola ama-x-ray muva nje. Phinda utshele udokotela wakho uma uke waba nesifo sezinso noma sesibindi.
• kufanele wazi ukuthi i-cyclophosphamide ingaphazamisa umjikelezo ojwayelekile wokuya esikhathini kwabesifazane futhi ingamisa ukukhiqizwa kwesidoda emadodeni. I-cyclophosphamide ingadala ukungabi nenzalo unomphela (ubunzima bokukhulelwa); noma kunjalo, akufanele ucabange ukuthi awukwazi ukukhulelwa noma ukuthi awukwazi ukukhulelisa omunye umuntu. Abesifazane abakhulelwe noma abancelisayo kufanele batshele odokotela babo ngaphambi kokuba baqale ukusebenzisa lo muthi. Akufanele uhlele ukuba nezingane ngenkathi uthola i-chemotherapy noma isikhashana ngemuva kokwelashwa. (Khuluma nodokotela wakho ukuthola eminye imininingwane.) Sebenzisa indlela ethembekile yokulawula inzalo ukuvimbela ukukhulelwa. ICyclophosphamide ingalimaza umbungu.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-cyclophosphamide.

Phuza uketshezi oluningi ngenkathi usebenzisa lo muthi.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Cyclophosphamide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla noma isisindo
• ubuhlungu besisu
• isifo sohudo
• ukulahleka kwezinwele
• izilonda emlonyeni noma olimini
• izinguquko kumbala wesikhumba
• izinguquko kumbala noma ukukhula kwezinzipho zeminwe noma zezinzwane

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• umphimbo obuhlungu, umkhuhlane, ukubanda, noma ezinye izimpawu zokutheleleka
• ukuphulukiswa kwesilonda esibi noma kancane
• ukulimaza noma ukopha okungavamile
• emnyama, izitulo zokubambezeleka
• ukuchama kabuhlungu noma umchamo obomvu
• ukuqubuka
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuphelelwa umoya
• ukukhwehlela
• ukuvuvukala emilenzeni, emaqakaleni, noma ezinyaweni
• ubuhlungu besifuba
• ukuphuzi kwesikhumba noma kwamehlo

ICyclophosphamide ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthatha i-cyclophosphamide.

I-Cyclophosphamide ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• emnyama, izitulo zokubambezeleka
• umchamo obomvu
• ukulimaza noma ukopha okungavamile
• ukukhathala okungajwayelekile noma ubuthakathaka
• umphimbo obuhlungu, ukukhwehlela, umkhuhlane, noma ezinye izimpawu zokutheleleka
• ukuvuvukala emilenzeni, emaqakaleni, noma ezinyaweni
• ubuhlungu besifuba

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-cyclophosphamide.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• ICytoxan^®¶

• I-CPM
• I-CTX
• I-CYT

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.