Ukuhlolwa kwe-ALT (Alanine Aminotransferase)

-Delile

• Kuyini ukuhlolwa kwe-ALT?
• Kungani kwenziwa ukuhlolwa kwe-ALT?
• Ngilungiselela kanjani ukuhlolwa kwe-ALT?
• Kwenziwa kanjani ukuhlolwa kwe-ALT?
• Ziyini izingozi ezihambisana nokuhlolwa kwe-ALT?
• Isho ukuthini imiphumela yami yokuhlolwa kwe-ALT?
• Imiphumela ejwayelekile
• Imiphumela engajwayelekile

Kuyini ukuhlolwa kwe-ALT?

Ukuhlolwa kwe-alanine aminotransferase (ALT) kukala izinga le-ALT egazini lakho. I-ALT iyi-enzyme eyenziwe ngamaseli esibindi sakho.

Isibindi yindlala enkulu kunazo zonke emzimbeni. Inemisebenzi eminingana ebalulekile, kufaka phakathi:

• okwenza amaprotheni
• ukugcina amavithamini kanye nensimbi
• kususa ubuthi egazini lakho
• ukukhiqiza i-bile, esiza ekugayeni

Amaprotheni abizwa ngama-enzyme asiza isibindi ukudiliza amanye amaprotheni ukuze umzimba wakho ukwazi ukuwamunca kalula. I-ALT ingenye yalezi enzyme. Idlala indima ebalulekile ekusetshenzisweni komzimba, inqubo eguqula ukudla kube ngamandla.

I-ALT ivame ukutholakala ngaphakathi kwamaseli wesibindi. Kodwa-ke, lapho isibindi sakho sonakele noma sihlaselwe, i-ALT ingakhishelwa egazini lakho. Lokhu kubangela ukuthi amazinga e-serum ALT akhuphuke.

Ukukala izinga le-ALT egazini lomuntu kungasiza odokotela ukuthi bahlole ukusebenza kwesibindi noma banqume imbangela yenkinga yesibindi. Ukuhlolwa kwe-ALT kuvame ukuba yingxenye yokuhlolwa kokuqala kwesifo sesibindi.

Ukuhlolwa kwe-ALT kwaziwa nangokuthi ukuhlolwa kwe-serum glutamic-pyruvic transaminase (SGPT) noma i-alanine transaminase test.

Kungani kwenziwa ukuhlolwa kwe-ALT?

Ukuhlolwa kwe-ALT kuvame ukusetshenziselwa ukunquma ukuthi ngabe othile unokulimala kwesibindi noma ukwehluleka. Udokotela wakho angalawula ukuhlolwa kwe-ALT uma unezimpawu zesifo sesibindi, kufaka phakathi:

• i-jaundice, ephuzi ngamehlo noma isikhumba sakho
• umchamo omnyama
• isicanucanu
• ukuhlanza
• ubuhlungu ku-quadrant engenhla kwesokudla sesisu sakho

Ukulimala kwesibindi ngokuvamile kubangela ukwanda kwamazinga e-ALT. Ukuhlolwa kwe-ALT kungahlola amazinga e-ALT egazini lakho, kodwa akukwazi ukukhombisa ukuthi kungakanani ukulimala kwesibindi okukhona noma ukuthi i-fibrosis, noma isibazi, sikhona kangakanani. Ukuhlolwa nakho akukwazi ukubikezela ukuthi ukulimala kwesibindi kuzoba kukhulu kangakanani.

Ukuhlolwa kwe-ALT kuvame ukwenziwa nezinye izivivinyo ze-enzyme yesibindi. Ukuhlola amazinga e-ALT kanye namazinga amanye ama-enzyme wesibindi kunganikeza udokotela wakho imininingwane ethe xaxa mayelana nenkinga yesibindi.

Ukuhlolwa kwe-ALT nakho kungenziwa ku:

• ukuqapha ukuqhubeka kwezifo zesibindi, njengokuhluleka kwesibindi noma ukwehluleka kwesibindi
• ukuhlola ukuthi kufanele kuqalwe yini ukwelashwa kwesifo sesibindi
• hlola ukuthi ukwelashwa kusebenza kanjani

Ngilungiselela kanjani ukuhlolwa kwe-ALT?

Ukuhlolwa kwe-ALT akudingi ukulungiswa okukhethekile. Kodwa-ke, kufanele utshele udokotela wakho nganoma imuphi umuthi kadokotela noma imishanguzo oyithengayo. Eminye imithi ingathinta amazinga e-ALT egazini lakho. Udokotela wakho angakutshela ukuthi ugweme ukuthatha imishanguzo ethile isikhathi esithile ngaphambi kokuhlolwa.

Kwenziwa kanjani ukuhlolwa kwe-ALT?

Ukuhlolwa kwe-ALT kuhilela ukuthatha isampula encane yegazi, njengoba kuchaziwe lapha:

1. Umhlinzeki wezokunakekelwa kwempilo usebenzisa isibulala-magciwane ukuhlanza isikhumba sakho endaweni lapho bezofaka khona inaliti.
2. Zibopha ibhande lokunwebeka engalweni yakho engenhla, evimba ukuphuma kwegazi futhi lenze imithambo engalweni yakho ibonakale kakhudlwana.
3. Uma sebethole umthambo, bafaka inaliti emthanjeni. Lokhu kungadala ukuzwa okuncane kokuncinza noma okuhlabayo. Igazi lidonswa kushubhu enamathiselwe ekugcineni kwenaliti. Kwezinye izimo, kungadingeka ithubhu engaphezu kweyodwa.
4. Ngemuva kokuqoqwa kwegazi elanele, umhlinzeki wezokunakekelwa kwezempilo ususa ibhande lokunwebeka nenaliti. Bafaka ucezu lukakotini noma lwe-gauze endaweni yokubhoboza bese bekumboza lokho ngebhandishi noma ngetheyiphu ukuyigcina isendaweni.
5. Isampuli yegazi ithunyelwa elabhorethri iyohlolwa.
6. I-laboratory ithumela imiphumela yokuhlolwa kudokotela wakho. Udokotela wakho angahlela i-aphoyintimenti nawe ukuze achaze imiphumela ngokuningiliziwe.

Ziyini izingozi ezihambisana nokuhlolwa kwe-ALT?

I-ALT ukuhlolwa kwegazi okulula okunezingozi ezimbalwa. Ukuqubuka kwesinye isikhathi kungavela endaweni lapho kufakwe khona inaliti. Ubungozi bokulimala bungancishiswa ngokufaka ingcindezi endaweni yokujova imizuzu embalwa ngemuva kokuthi inaliti isusiwe.

Ezimweni ezingavamile kakhulu, lezi zinkinga ezilandelayo zingenzeka ngesikhathi noma ngemuva kokuhlolwa kwe-ALT:

• ukopha ngokweqile lapho kwafakwa khona inaliti
• ukuqoqwa kwegazi ngaphansi kwesikhumba sakho, okubizwa nge-hematoma
• ikhanda elikhanyayo noma ukuquleka lapho ubona igazi
• ukutheleleka endaweni yokubhoboza

Isho ukuthini imiphumela yami yokuhlolwa kwe-ALT?

Imiphumela ejwayelekile

Inani elijwayelekile le-ALT egazini lisukela kumayunithi angama-29 kuye kwangama-33 ilitha ngalinye (IU / L) labesilisa kanye ne-19 kuya ku-25 IU / L labesifazane, kepha leli nani lingahluka ngokuya ngesibhedlela. Lobu bubanzi bungathinteka ngezici ezithile, kufaka phakathi ubulili nobudala. Kubalulekile ukuxoxa ngemiphumela yakho ethile nodokotela wakho.

Imiphumela engajwayelekile

Amazinga aphezulu kunejwayelekile we-ALT angakhombisa ukulimala kwesibindi. Amazinga akhuphukile e-ALT angaba ngumphumela we:

• i-hepatitis, okuyisimo sokuvuvukala kwesibindi
• i-cirrhosis, okuyisibazi esikhulu sesibindi
• ukufa kwezicubu zesibindi
• isimila noma umdlavuza esibindini
• ukungabi khona kwegazi eliya esibindi
• i-hemochromatosis, okuyisifo esidala ukuthi insimbi yakhele emzimbeni
• i-mononucleosis, okutheleleka okuvame ukubangelwa igciwane le-Epstein-Barr
• i-pancreatitis, okuwukuvuvukala kwamanyikwe
• isifo sikashukela

Imiphumela eminingi ye-ALT esezingeni eliphansi ikhombisa isibindi esinempilo. Kodwa-ke, kukhombisile ukuthi imiphumela engaphansi kokujwayelekile ibihlobene nokwanda kokushona kwesikhathi eside. Xoxa ngezinombolo zakho ngqo nodokotela wakho uma ukhathazekile ngokufunda okuphansi.

Uma imiphumela yakho yokuhlolwa ikhombisa ukulimala kwesibindi noma isifo, ungadinga ukuhlolwa okwengeziwe ukuthola imbangela yenkinga kanye nendlela engcono yokuyelapha.