Okudingeka Ukwazi Ngaphambi Kokuthatha I-Amitriptyline Yokulala

-Delile

• Yini i-amitriptyline?
• Yini okushiwo ngaphandle kwelebula?
• Izexwayiso ze-FDA mayelana ne-amitriptyline
• Isebenza kanjani i-amitriptyline?
• Uyini umthamo ojwayelekile lapho unqunyelwe ukulala?
• Ingabe kunemiphumela engemihle ekuthatheni i-amitriptyline yokulala?
• Imiphumela emibi ejwayelekile
• Imiphumela emibi kakhulu
• Ingabe kukhona ukuxhumana nezinye izidakamizwa?
• Ingabe zikhona izexwayiso mayelana nokuthatha i-amitriptyline ukulala?
• Ziyini izinzuzo zokuthatha i-amitriptyline ukulala?
• Okubalulekile

Ukuntula ukulala okungapheli kungaphezu nje kokukhungatheka. Kungaba nomthelela kuzo zonke izingxenye zempilo yakho kubandakanya impilo yomzimba nengqondo. I-Centers for Disease Control and Prevention (CDC) ibika ukuthi ngaphezu kwabantu abadala baseMelika abatholi ukulala ngokwanele.

Uma ungakutholi ukulala okudingayo, kunezindlela zokwelapha ezahlukahlukene, kufaka phakathi imishanguzo engasiza.

Imithi yokulala isebenza ngezindlela ezahlukahlukene ukukusiza ukuthi ulale noma ulale. Udokotela wakho angaxoxa ngokuyalela i-amitriptyline (Elavil, Vanatrip) ukukusiza ulale.

Uma uzama ukunquma ukuthi i-amitriptyline ikulungele yini, nazi ezinye izinto okufanele uzicabangele.

Yini i-amitriptyline?

I-Amitriptyline ngumuthi kadokotela otholakala njengethebhulethi ngamandla amaningi. Kuvunyelwe ukusetshenziswa ukwelapha ukucindezeleka kepha futhi kuvame ukunikezwa ezinye izimo eziningana ezinjengezinhlungu, i-migraines, nokuqwasha.

Yize sekuneminyaka eminingi ikhona, kusengumuthi ojwayelekile, obiza izindleko ophansi.

Yini okushiwo ngaphandle kwelebula?

I-Amitriptyline ivunyelwe yi-Food and Drug Administration (FDA) ukwelapha ukucindezeleka, kepha odokotela baphinde banikeze umuthi ukusiza ngokulala. Lapho udokotela echaza umuthi wokusetshenziswa ngaphandle kwalowo ovunyelwe yi-FDA, kwaziwa njengokusebenzisa amalebula angekho.

Odokotela banikeza i-off-label ngezizathu eziningana kufaka phakathi:

• Ubudala. Udokotela anganikeza umuthi kothile omncane noma omdala kunalokho okuvunyelwe ilebula lezidakamizwa le-FDA.
• Inkomba noma ukusetshenziswa. Umuthi ungabekelwa isimo ngaphandle kwaleyo evunyelwe yi-FDA.
• Umthamo. Udokotela anganikeza umthamo ophansi noma ophakeme kunalokho okufakwe ohlwini kwilebula noma nge-FDA enconyiwe.

I-FDA ayenzi izincomo kodokotela ngendlela yokuphatha iziguli. Kukudokotela wakho ukuthi anqume ukwelashwa okungcono kakhulu kuwe ngokuya ngobungcweti babo nangokuthanda kwakho.

Izexwayiso ze-FDA mayelana ne-amitriptyline

I-Amitriptyline "inesixwayiso sebhokisi elimnyama" esivela ku-FDA. Lokhu kusho ukuthi umuthi unemiphumela ethile ebalulekile obhekene nayo nodokotela wakho ngaphambi kokuthatha lo muthi.

• I-Amitriptyline inyuse ubungozi bokucabanga ukuzibulala nokuziphatha kwabanye abantu, ikakhulukazi izingane kanye nabantu abadala. Kubalulekile ukuqapha ukwanda kwezimpawu zemizwelo, imicabango, noma indlela yokuziphatha bese ushayela u-911 ngokushesha uma ubona izinguquko.
• Ungashayela neNational Suicide Prevention Lifeline ku-800-273-8255 uma wena noma omunye umuntu omaziyo enemicabango yokuzibulala.
• I-Amitriptyline ayivunyelwe yi-FDA ukuthi isetshenziswe ezinganeni ezingaphansi kuka-12.

Isebenza kanjani i-amitriptyline?

I-Amitriptyline wuhlobo lomuthi obizwa nge-tricyclic antidepressant (TCA). Le mithi isebenza ngokwandisa amakhemikhali athile obuchopho abizwa ngama-neurotransmitters afana ne-serotonin ne-norepinephrine ukusiza ukuthuthukisa imizwa, ukulala, ubuhlungu nokukhathazeka.

Akucaci kahle ukuthi i-amitriptyline isebenzela kanjani ukulala, kodwa omunye wemiphumela yayo ukuvimba i-histamine, engahle yehle ukozela. Lesi ngesinye sezizathu esenza odokotela banikeze i-amitriptyline njengosizo lokulala.

Uyini umthamo ojwayelekile lapho unqunyelwe ukulala?

I-Amitriptyline yokulala inqunywe ngamanani ahlukene. Umthamo uzoncika ezintweni eziningi ezinjengeminyaka yakho yobudala, eminye imithi okungenzeka ukuthi uyayithatha, isimo sakho sezokwelapha, nezindleko zezidakamizwa.

Kubantu abadala, umthamo uvame ukuba phakathi kwama-milligram angama-50 kuya kwayi-100 ngesikhathi sokulala. Intsha kanye nabantu abadala bangathatha imithamo ephansi.

Uma unokwehluka okuthile kofuzo okwaziwayo njengokushintshwa kwezakhi zofuzo, ungadinga ukulungiswa komthamo ukunciphisa amathuba emiphumela emibi nge-amitriptyline.

Cabanga ukubuza udokotela wakho noma usokhemisi ngokuhlolwa kofuzo okubizwa nge-pharmacogenomics. Lokhu sekuthandwa kakhulu ukusiza imishanguzo yakho ibe ngeyakho ukuze ikusebenzele kangcono.

Ukuqala ngomthamo ophansi kusiza udokotela ukuthi abone ukuthi usabela kanjani emithini ngaphambi kokwenza ushintsho.

Ingabe kunemiphumela engemihle ekuthatheni i-amitriptyline yokulala?

I-Amitriptyline ingaba nemiphumela emibi ethile. Ngaphambi kokuthatha lo muthi, qiniseka ukwazisa udokotela wakho uma ngabe uke waba neguliswa i-amitriptyline noma ezinye izidakamizwa, noma uma uke waba nemicabango yokuzibulala noma indlela yokuziphatha.

Yazisa udokotela wakho uma unayo:

• isifo senhliziyo, isibindi noma izinkinga zezinso
• i-glaucoma, njengoba i-amitriptyline ingakhuphula ingcindezi esweni lakho
• isifo sikashukela, njengoba i-amitriptyline ingathinta amazinga akho kashukela, ngakho-ke kungadingeka ukuthi uhlole ushukela wakho kaningi lapho uqala ukuthatha i-amitriptyline
• isithuthwane, njengoba i-amitriptyline ingakhuphula ubungozi bokuquleka
• i-bipolar disorder, mania, noma i-schizophrenia

Khuluma nodokotela wakho uma ukhulelwe noma uncelisa. Ucwaningo alukwenzi kucace ngokuqinisekile ukuthi ngabe i-amitriptyline iphephile yini ukusebenzisa ngesikhathi sokukhulelwa noma uma uncelisa.

Imiphumela emibi ejwayelekile

Lapho uqala ukuthatha i-amitriptyline, ungahle ube nemiphumela engemihle. Imvamisa ziyahamba ngemuva kwezinsuku ezimbalwa. Khuluma nosokhemisi noma udokotela wakho uma behlupha bese uqhubeka.

• umlomo owomile
• ikhanda
• ukuzuza kwesisindo
• ukuqunjelwa
• inkinga yokuchama
• ukwehla okungazelelwe kwengcindezi yegazi ikakhulukazi lapho umile lapho uhleli khona
• ukozela noma isiyezi
• ukungaboni kahle
• izandla eziqhaqhazelayo (ukuthuthumela)

Imiphumela emibi kakhulu

Yize kungavamile, i-amitriptyline ingadala imiphumela emibi kakhulu. Shayela u-911 khona manjalo uma uhlangabezana nesimo esiphuthumayo esisongela impilo.

Shayela u-911 khona manjalo uma uhlangabezana nenye yalezi zimpawu ngenkathi uthatha i-amitriptyline, njengoba ingakhombisa isimo esiphuthumayo esisongela impilo:

• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• ubuhlungu besifuba nokuphefumula okuncane, okungakhombisa ukuhlaselwa yinhliziyo
• ubuthakathaka ohlangothini olulodwa lomzimba noma inkulumo engacacile, engakhombisa ukushaywa unhlangothi

Ungahle uhlangabezane nezinye izimpawu ezingekho ohlwini lapha. Hlala ukhuluma nodokotela wakho ngalokho ongahle ubhekane nakho ukuze ufunde uma ngabe umuthi wakho unesibopho.

Ingabe kukhona ukuxhumana nezinye izidakamizwa?

I-Amitriptyline ingaxhumana nemithi eminingana. Kubalulekile ukuvumela udokotela wakho kanye nosokhemisi ukuthi bazi yonke imishanguzo kadokotela, imishanguzo yokuthenga, nezithako zokudla ozithathayo ukugwema ukusabela okungathi sína.

Imithi ejwayelekile kakhulu esebenzisana ne-amitriptyline ifaka:

• i-monoamine oxidase inhibitors (i-MAOIs) efana ne-selegiline (i-Eldepryl): ingadala ukuquleka noma ukufa
• I-quinidine: ingadala izinkinga zenhliziyo
• imithi ye-opioid efana ne-codeine: ingakhuphula ukozela futhi inyuse ingozi ye-serotonin syndrome, engadala ukwanda kwengcindezi yegazi nokukhuphuka kwenhliziyo
• i-epinephrine ne-norepinephrine: ingakhuphula umfutho wegazi, ikhanda elibuhlungu, nobuhlungu besifuba
• I-topiramate: ingadala amazinga aphezulu we-amitriptyline emzimbeni wakho, ikhuphule ubungozi bemiphumela emibi

Lolu akulona uhlu oluphelele. Kunezinye izidakamizwa eziningana ezingasebenzisana ne-amitriptyline. Buza nodokotela wakho uma unezinkinga ezithile.

Ingabe zikhona izexwayiso mayelana nokuthatha i-amitriptyline ukulala?

Kuze kube yilapho umzimba wakho ujwayela umuthi, qaphela nganoma yimiphi imisebenzi edinga ukuthi uqaphele njengemishini yokushayela noma yokusebenza.

Akufanele uphuze utshwala noma uthathe eminye imithi engakwenza ukozele nge-amitriptyline ngoba ingakhuphula umphumela womuthi.

Akufanele uyeke ngokungazelelwe ukuthatha i-amitriptyline. Khuluma nodokotela wakho mayelana nendlela engcono kakhulu yokumisa kancane kancane lo muthi.

Ziyini izinzuzo zokuthatha i-amitriptyline ukulala?

Izinzuzo ezimbalwa ze-amitriptyline zifaka:

• Okungabizi kakhulu. I-Amitriptyline umuthi omdala otholakala njengomuthi ojwayelekile, ngakho-ke awubizi uma uqhathaniswa nezinye izinsiza zokulala ezintsha.
• Hhayi umkhuba ukwakha. I-Amitriptyline ayiyona umlutha noma umkhuba owakhekayo njengeminye imithi esetshenziselwa ukuqwasha njenge-diazepam (Valium)

I-Amitriptyline ingasiza uma ukuqwasha kungumphumela wesinye isimo ongahle ube naso, njengobuhlungu, ukudangala noma ukukhathazeka. Kufanele uxoxe ngazo zonke izimpawu zakho nodokotela wakho ukuze akutholele indlela engcono kakhulu yokwelashwa.

Okubalulekile

I-Amitriptyline ibilokhu ikhona iminyaka eminingi futhi iyindlela engabizi kakhulu njengosizo lokulala. I-Amitriptyline kanye ne-anti-depressants efana nayo kuvame ukusetshenziswa ngaphandle kwelebula ukwelapha ukuqwasha, ikakhulukazi kubantu abanezimpawu zokucindezeleka.

I-Amitriptyline ingadala imiphumela emibi kakhulu futhi ingaxhumana neminye imithi. Uma ucabangela i-amitriptyline ukukusiza ukuba uthole ukulala ngokwengeziwe, qiniseka ukuthi ukhuluma nodokotela wakho nganoma yimiphi eminye imishanguzo kanye nezithasiselo osuvele uzithatha.