Ukuhlolwa kwe-ANA (Antinuclear Antibody)

-Delile

• Luyini uvivinyo lwe-ANA (antinuclear antibody)?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwe-ANA?
• Kwenzekani ngesikhathi sokuhlolwa kwe-ANA?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi esivivinyweni?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwe-ANA?
• Izinkomba

Luyini uvivinyo lwe-ANA (antinuclear antibody)?

Ukuhlolwa kwe-ANA kubheka amasosha omzimba aphikisana negazi lakho. Uma ukuhlolwa kuthola amasosha omzimba enyukliya egazini lakho, kungasho ukuthi unenkinga yokuzilimaza komzimba. Isifo sokuzivikela komzimba senza ukuthi amasosha omzimba wakho ahlasele amaseli akho, izicubu, kanye / noma izitho ngephutha. Lezi zinkinga zingadala izinkinga ezinkulu zempilo.

Ama-antibody amaprotheni enziwa amasosha akho omzimba ukulwa nezinto zangaphandle njengamagciwane namagciwane. Kepha i-anti-nuclear antibody ihlasela amangqamuzana akho aphilile esikhundleni salokho. Ibizwa nge- "antinuclear" ngoba ihlose i-nucleus (maphakathi) yamaseli.

Amanye amagama: iphaneli ye-antinuclear antibody, i-fluorescent antinuclear antibody, i-FANA, i-ANA

Kusetshenziselwa ini?

Ukuhlolwa kwe-ANA kusetshenziselwa ukusiza ukuxilonga ukuphazamiseka komzimba, kufaka phakathi:

• Uhlelo lwe-lupus erythematosus (SLE). Lolu uhlobo oluvame kakhulu lwe-lupus, isifo esingelapheki esithinta izingxenye eziningi zomzimba, kufaka phakathi amalunga, imithambo yegazi, izinso nobuchopho.
• I-rheumatoid arthritis, isimo esidala ubuhlungu nokuvuvukala kwamalunga, ikakhulukazi ezandleni nasezinyaweni
• I-Scleroderma, isifo esingajwayelekile esithinta isikhumba, amalunga nemithambo yegazi
• I-Sjogren's syndrome, isifo esingajwayelekile esithinta izindlala zokwenza umswakama womzimba

Kungani ngidinga ukuhlolwa kwe-ANA?

Umhlinzeki wakho wokunakekelwa kwezempilo anga-oda ukuhlolwa kwe-ANA uma unezimpawu ze-lupus noma esinye isifo se-autoimmune. Lezi zimpawu zifaka:

• Imfiva
• Ukuqhuma okubomvu, okuvemvane (uphawu lwe-lupus)
• Ukukhathala
• Ubuhlungu obuhlangene nokuvuvukala
• Ubuhlungu bemisipha

Kwenzekani ngesikhathi sokuhlolwa kwe-ANA?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi amalungiselelo akhethekile wokuhlolwa kwe-ANA.

Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Umphumela omuhle ekuhlolweni kwe-ANA usho ukuthi amasosha omzimba aphikisayo atholakala egazini lakho. Ungathola imiphumela emihle uma:

• Une-SLE (lupus).
• Unohlobo olwehlukile lwezifo ezizimele.
• Unesifo segciwane.

Umphumela omuhle awusho ukuthi unesifo. Abanye abantu abaphilile banamasosha omzimba aphikisana negazi. Ngaphezu kwalokho, imithi ethile ingathinta imiphumela yakho.

Uma imiphumela yakho yokuhlolwa kwe-ANA ilungile, umhlinzeki wakho wezokunakekelwa kwempilo kungenzeka a-oda izivivinyo eziningi, ikakhulukazi uma unezimpawu zezifo. Uma unemibuzo ngemiphumela yakho, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwe-ANA?

Amazinga e-antibacteria anti-nuclear avame ukwanda ngokuguga. Abangaba yingxenye eyodwa kwezintathu yabantu abadala abanempilo engaphezu kweminyaka engama-65 bangaba nemiphumela yokuhlolwa eyi-ANA.

Izinkomba

1. I-American College of Rheumatology [i-Intanethi]. I-Atlanta: Ikholeji yaseMelika yeRheumatology; c2017. Ama-Antinuclear Antibodies (ANA); [kubuyekezwe u-2017 Mar; kukhonjiwe ngo-2017 Nov 17]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Antinuclear-Antibodies-ANA
2. UHinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Test. 2nd Ed, Kindle. IPhiladelphia: I-Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Ama-Antinuclear Antibodies (ANAS); k. 53
3. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2018. I-Antinuclear Antibody (ANA); [kubuyekezwe 2018 Feb 1; kukhonjiwe ngo-2018 Feb 8]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/understanding/analytes/ana/tab/test
4. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2018. I-Scleroderma; [kubuyekezwe i-2017 Sep 20; kukhonjiwe ngo-2018 Feb 8]; [cishe izikrini ezi-2]. Kutholakala ku: https://labtestsonline.org/understanding/conditions/scleroderma
5. ILupus Research Alliance [i-Intanethi]. ENew York: I-Lupus Research Alliance; c2017. Mayelana neLupus; [kucashunwe ngo-2017 Nov 17]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.lupusresearch.org/understanding-lupus/what-is-lupus/about-lupus
6. ILupus Research Alliance [i-Intanethi]. ENew York: I-Lupus Research Alliance; c2017. Izimpawu; [kucashunwe ngo-2017 Nov 17]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.lupusresearch.org/understanding-lupus/what-is-lupus/symptoms
7. Uhlobo Lokuthengwa Kwamakhasimende we-Merck [Internet]. IKenilworth (NJ): IMerck & Co, Inc .; c2017. ISjögren's Syndrome; [kucashunwe ngo-2017 Nov 17]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.merckmanuals.com/home/bone,-joint,-and-muscle-disorders/autoimmune-disorders-of-connective-tissue/sj%C3%B6gren-syndrome
8. Uhlobo Lokuthengwa Kwamakhasimende we-Merck [Internet]. IKenilworth (NJ): IMerck & Co, Inc .; c2017. I-Systemic Lupus Erythematosus (SLE); [kucashunwe ngo-2017 Nov 17]; [cishe izikrini ezi-3]. Kutholakala kusuka: http://www.merckmanuals.com/home/bone,-joint,-and-muscle-disorders/autoimmune-disorders-of-connective-tissue/systemic-lupus-erythematosus-sle
9. IMayo Clinic [Inthanethi]. IMayo Foundation for Medical Education and Research; c1998–2017. Ukuhlolwa kwe-ANA: Ukubuka konke; 2017 Aug 3 [icashunwe ngoNovemba 17]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.mayoclinic.org/tests-procedures/ana-test/home/ovc-20344718
10. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuhlolwa Kwegazi; [kucashunwe ngo-2018 Feb 8]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
11. I-NIH U.S. National Library of Medicine: Isethenjwa Sasekhaya se-Genetics [Internet]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. isifo samathambo; 2017 Nov 14 [kucashunwe 2017 Nov 17]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ghr.nlm.nih.gov/condition/rheumatoid-arthritis
12. Impilo ye-UF: University of Florida Health [Internet]. Inyuvesi yaseFlorida; c2017. Iphaneli ye-antiinuclear antibody: Ukubuka konke [kubuyekezwe ngo-2017 Nov 17; kukhonjiwe ngo-2017 Nov 17]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/antinuclear-antibody-panel
13. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2017. I-Health Encyclopedia: I-Antinuclear Antibody; [kucashunwe ngo-2017 Nov 17]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=antinuclear_antibodies
14. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2017. Ama-Antinuclear Antibodies (ANA): Imiphumela; [kubuyekezwe i-2016 Oct 31; kukhonjiwe ngo-2017 Nov 17]; [cishe izikrini eziyi-8]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/medicaltest/antinuclear-antibodies/hw2297.html#hw2323
15. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2017. Ama-Antinuclear Antibodies (ANA): Ukubuka konke kokuhlolwa; [kubuyekezwe i-2016 Oct 31; kukhonjiwe ngo-2017 Nov 17]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/medicaltest/antinuclear-antibodies/hw2297.html
16. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2017. Ama-Antinuclear Antibodies (ANA): Kungani Kwenziwe; [kubuyekezwe i-2016 Oct 31; kukhonjiwe ngo-2017 Nov 17]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/medicaltest/antinuclear-antibodies/hw2297.html#hw2304

Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.