Buza Udokotela Wokudla: Iqiniso Mayelana ne-5-HTP

-Delile

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Umbuzo: Ingabe ukuthatha i-5-HTP kuzongisiza ngehlise isisindo?

A: Mhlawumbe akunjalo, kodwa kuya ngokuthi. I-5-hydroxy-L-tryptophan iphuma ku-amino acid tryptophan futhi iguqulelwa ku-neurotransmitter serotonin ebuchosheni. Lokho kuhlangene ngani nokuncipha kwesisindo? ISerotonin iyi-neurotransmitter enezici eziningi, futhi enye yezindima zayo inethonya lokudla. (Wake waba ku-coma eyenziwe nge-carb lapho isifiso sakho sachithwa ngokuphelele? USerotonin waba nesandla kulokho.)

Ngenxa yalokhu kuxhunywa nendlala, ukuguqula amazinga e-serotonin nemiphumela yokuthola ukunciphisa umzimba sekuyisikhathi eside kukuphishekela izinkampani zemithi. Enye yezidakamizwa ezidume kakhulu (noma ezingadumile) zokunciphisa isisindo, i-Phentermine, yaba nomthelela omncane ekukhululweni kwe-serotonin.

Uma kukhulunywa ngocwaningo lwangempela nge-5-HTP nomthelela wayo ekunciphiseni isisindo, ngeke uthole okuningi. Kwesinye isifundo esincane, abacwaningi base-Italy babeka iqembu labantu abadala abakhuluphele, i-hyperphagic (isayensi "yokudla kakhulu") ekudleni okunama-kilojoule angu-1,200 futhi banikeze ingxenye yabo i-300 milligrams ye-5-HTP ukuthatha imizuzu engu-30 ngaphambi kokudla ngakunye. Ngemva kwamasonto angu-12, laba bahlanganyeli balahlekelwa cishe ngamakhilogremu angu-7.2 uma kuqhathaniswa namakhilogremu angu-4 kulo lonke iqembu, labo, ngokungazi, bathatha indawo ye-placebo.

Okubalulekile okumele sikuqaphele ukuthi nakuba ukuncipha kwesisindo seqembu le-placebo kwakungabalulekile ngokwezibalo, phakathi nengxenye yesibili yocwaningo, bonke ababambiqhaza banikezwe isiqondiso esithile sokunciphisa ukudla kwabo kwekhalori. Iqembu lamaphilisi kashukela ligeje umaki wekhalori cishe ngamakhalori angama-800. Kimi lokhu kubonakala kufana nokungalandeli imiyalelo kunomphumela wesengezo.

Futhi ngenkathi kubonakala sengathi i-5-HTP kungenzeka isizile ekunciphiseni isisindo, kumuntu okhuluphele ngokweqile ukwehlisa amakhilogremu ayi-7 emasontweni ayi-12 ngenkathi edla nokudla okunomkhawulo wekhalori akuyona leyo nto ephawulekayo.

Ngaphandle kwalolu cwaningo, akukho okuningi-ngaphandle kwe-hypotheses kanye nezinqubo ze-biochemical-ukukhombisa ukuthi i-5-HTP iyicindezela yokudla. Uma uzivocavoca njalo futhi ulandela uhlelo lokudla olunomkhawulo wekhalori- ne-carbohydrate, ngibe nesikhathi esinzima sokubona inzuzo yokwengeza nge-5-HTP.

Uma usenentshisekelo yokuthatha i-5-HTP, yazi ukuthi imakethwa kalula njengebonakala iphephile futhi inemiphumela engemihle, kepha noma ngubani othatha imishanguzo, engasiza ngeshwa ekuzuzeni isisindo, kufanele agweme ukuthatha isengezo, ngoba singadlala umphumela kanye nomthamo odingekayo we-serotonin kuma-anti-depressants.

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