Ingabe i-Aspirin ingakusiza ukudambisa ubuhlungu bakho be-Migraine?

-Delile

• Uthini ucwaningo?
• Isebenza kanjani i-aspirin ekunciphiseni i-migraine?
• Okufanele ukwazi ngomthamo
• Ingabe i-aspirin ikulungele?
• Ingabe ikhona imiphumela engemihle?
• Imiphumela emibi ejwayelekile
• Imiphumela emibi kakhulu
• Ukusebenzisana kwezidakamizwa
• Yini enye engasiza ekunciphiseni izimpawu ze-migraine?
• Indlela yokuphila nezinketho zemvelo
• Okubalulekile

I-Migraine ibangela ubuhlungu obukhulu, obuhluphayo obungahlala emahoreni ambalwa kuye ezinsukwini ezimbalwa. Lokhu kuhlaselwa kungahle kuhambisane nezinye izimpawu, ezifana nesicanucanu nokuhlanza, noma ukukhuphuka kokuzwela ekukhanyeni nasemisindweni.

I-Aspirin iyisidakamizwa esaziwa nge-over-the-counter nonsteroidal anti-inflammatory (NSAID) esisetshenziselwa ukwelapha ubuhlungu obumaphakathi kuya kokulingene nokuvuvukala. Iqukethe isithako esisebenzayo se-acetylsalicylic acid (ASA).

Kule ndatshana, sizobheka ngokucophelela ubufakazi bomtholampilo maqondana nokusetshenziswa kwe-aspirin njengokwelashwa kwe-migraine, isilinganiso esinconywayo, kanye nemiphumela emibi engaba khona.

Uthini ucwaningo?

Ucwaningo oluningi olutholakalayo lubonisa ukuthi umthamo ophakeme we-aspirin usebenza ekunciphiseni ubuhlungu nokuvuvukala okuhambisana ne-migraine.

Ukubuyekezwa kwemibhalo ka-2013 kuhlolwe izifundo ezisezingeni eliphakeme eziyi-13 ngenani labahlanganyeli abangu-4,222. Abaphenyi babika ukuthi umthamo we-aspirin othathwe ngomlomo unamandla oku:

• hlinzeka ukukhululeka ku-migraine kungakapheli amahora amabili ngamaphesenti ama-52 wabasebenzisi be-aspirin, uma kuqhathaniswa namaphesenti angama-32 abathathe i-placebo
• ukunciphisa ubuhlungu bekhanda kusuka ekulinganiseni noma obukhulu ngaphandle kobuhlungu nhlobo kubantu abangu-1 kwabangu-4 abathathe le dose ye-aspirin, uma kuqhathaniswa no-1 kwabayishumi abathathe i-placebo
• ukunciphisa isicanucanu ngempumelelo uma kuhlangene ne-anti-nausea drug metoclopramide (Reglan) kunokusebenzisa i-aspirin kuphela

Abaphenyi balokhu kubuyekezwa kwezincwadi baphinde babika ukuthi i-aspirin isebenza njenge-low low sumatriptan, umuthi ovamile we-acute migraine, kepha awusebenzi njenge-high dose sumatriptan.

Ukubuyekezwa kwezincwadi zango-2020 kubike imiphumela efanayo. Ngemuva kokuhlaziya izivivinyo ze-13 ezingahleliwe, ababhali baphetha ngokuthi umthamo ophakeme we-aspirin uyindlela yokwelashwa ephephile nephumelelayo ye-migraine.

Ababhali baphinde babika ukuthi umthamo ophansi, wansuku zonke we-aspirin kungaba yindlela ephumelelayo yokuvimbela i-migraine engapheli. Lokhu-ke, kuya ngesimo sakho futhi kufanele ukhulume nodokotela wakho ngaphambi kokuqala noma imuphi umuthi wansuku zonke.

Lokhu okutholakele kusekelwe ukubuyekezwa kwezincwadi zango-2017 zezifundo eziyisishiyagalombili ezisezingeni eliphakeme. Ababhali baphethe ngokuthi umthamo wansuku zonke we-aspirin unganciphisa imvamisa yokuhlaselwa kwe-migraine.

Ngokufingqa, ngokusho kocwaningo lomtholampilo, i-aspirin ibonakala isebenza kubo bobabili:

• ukunciphisa ubuhlungu obunzima be-migraine (umthamo omkhulu, njengoba kudingeka)
• ukunciphisa imvamisa ye-migraine (umthamo ophansi, wansuku zonke)

Ngaphambi kokuba uqale ukuthatha i-aspirin njengendlela yokuvimbela, qhubeka ufunda ukuthola ukuthi isebenza kanjani nokuthi kungani odokotela abaningi bengayincomi.

Isebenza kanjani i-aspirin ekunciphiseni i-migraine?

Yize singazi ukuthi iyiphi indlela efanele yokusebenza kwe-aspirin ekwelapheni i-migraine, lezi zakhiwo ezilandelayo kungenzeka ziyasiza:

• I-analgesic. I-Aspirin iyasebenza ekwehliseni ubuhlungu obumaphakathi kuya kokulingene nokuvuvukala. Isebenza ngokuvimbela ukukhiqizwa kwama-prostaglandin, amakhemikhali afana ne-hormone adlala indima ebuhlungwini.
• Ukulwa nokuvuvukala. Ama-Prostaglandins nawo afaka isandla ekuvukeleni. Ngokuvimba ukukhiqizwa kwe-prostaglandin, i-aspirin ibuye ihlose ukuvuvukala, okuyisici ekuhlaselweni yi-migraine.

Okufanele ukwazi ngomthamo

Udokotela wakho uzocubungula izinto eziningi ukunquma ukuthi iyiphi i-aspirin ephephile ongayithatha. Uma udokotela wakho ebona ukuthi i-aspirin iphephile kuwe, isilinganiso esinconyiwe sizoxhomeka ebukhali, ubude besikhathi, kanye nobuningi bezimpawu zakho ze-migraine.

Ucwaningo lwamuva luphakamisa imithamo elandelayo ye-migraine:

• I-900 kuya ku-1,300 mg ekuqaleni kokuhlaselwa kwe-migraine
• I-81 kuya ku-325 mg ngosuku yokuhlaselwa okuphindaphindiwe kwe-migraine

Kufanele ukhulume nodokotela wakho ngokusetshenziswa kwe-aspirin yokuvimbela ukuhlaselwa yi-migraine. I-American Headache Society incoma ukuthi kunqunywe izindlela zokwelapha ekuvivinyweni kwezinyanga ezimbili kuya kwezintathu ukugwema ukusetshenziswa ngokweqile.

Ukuthatha i-aspirin ngokudla kungasiza ekunciphiseni ubungozi bemiphumela emibi yamathumbu.

Ingabe i-aspirin ikulungele?

I-Aspirin ayilungele wonke umuntu. Izingane ezingaphansi kweminyaka engu-16 akufanele zithathe i-aspirin. I-Aspirin ingakhuphula ingozi yengane yokuthuthukisa i-Reye's syndrome, isifo esingajwayelekile kodwa esibi esidala ukulimala kwesibindi nobuchopho.

I-Aspirin ibeka ubungozi obengeziwe kubantu abanakho noma abake baba nabo njengamanje:

• ukungezwani komzimba nama-NSAID
• izinkinga zokuvala igazi
• ukuvuvukala
• izikhathi ezinzima zokuya esikhathini
• isifo sesibindi noma sezinso
• izilonda zesisu noma ukopha emathunjini
• ukopha ngaphakathi kobuchopho noma olunye uhlelo lwesitho

Yazisa udokotela wakho uma ukhulelwe. I-Aspirin ingasetshenziswa ezimweni ezikhethekile ngesikhathi sokukhulelwa njengesifo sokuqina. Akunconywa ngaphandle uma kunesimo sezempilo esiyisisekelo esivumayo.

Ingabe ikhona imiphumela engemihle?

Njengezidakamizwa eziningi, i-aspirin iza nengozi yemiphumela emibi engaba khona. Lezi zingaba mnene noma zibe zimbi kakhulu. Uthatha i-aspirin engakanani nokuthi uyithatha kaningi kangakanani ingakhuphula ubungozi bakho bemiphumela emibi.

Kubalulekile ukukhuluma nodokotela wakho ngomthamo wakho we-aspirin ukunciphisa ubungozi bemiphumela emibi engaba khona. Kubalulekile ukuthi ungathathi i-aspirin nsuku zonke ngaphandle kokuqala ukhulume nodokotela wakho.

Imiphumela emibi ejwayelekile

• isisu esibuhlungu
• ukugaya ukudla
• isicanucanu
• ukopha nokulimala kalula

Imiphumela emibi kakhulu

• ukopha esiswini
• ukwehluleka kwezinso
• ukulimala kwesibindi
• isifo sohlangothi esopha kakhulu
• i-anaphylaxis, ukusabela okungekuhle komzimba

Ukusebenzisana kwezidakamizwa

I-Aspirin ingasebenzisana nezinye izidakamizwa ozisebenzisayo. Kubalulekile ukuthi ungathathi i-aspirin nge:

• ezinye izinciphisi zegazi, njenge-warfarin (Coumadin)
• i-defibrotide
• dichlorphenamide
• imijovo yemikhuhlane ephilayo
• i-ketorolac (Toradol)

Qiniseka ukuthi unikeza udokotela wakho uhlu oluphelele lwemithi kadokotela nemishanguzo engeyona kadokotela, izengezo zamakhambi, namavithamini owathathayo ukugwema ukuhlangana okungenzeka.

Yini enye engasiza ekunciphiseni izimpawu ze-migraine?

I-Aspirin ingenye yemithi eminingi engasiza ekunciphiseni i-migraine.

Udokotela wakho uzocubungula izinto ezahlukahlukene - njengokuthi i-migraine yakho ikhula ngokushesha kangakanani nokuthi unazo yini ezinye izimpawu - lapho unquma ukuthi imiphi imithi ekufanele.

Imithi evame ukubekelwa ukuhlaselwa okunamandla kwe-migraine ifaka:

• amanye ama-NSAID, njenge-ibuprofen (Advil, Motrin) noma naproxen (Aleve, Naprosyn)
• ama-triptan, njenge-sumatriptan, i-zolmitriptan, noma i-naratriptan
• i-ergot alkaloids, efana ne-dihydroergotamine mesylate noma i-ergotamine
• ojantshi
• imisele

Uma unesilinganiso sezinsuku ezine noma ngaphezulu zokuhlaselwa kwe-migraine ngenyanga, udokotela wakho angahle anikeze nezidakamizwa ukunciphisa imvamisa yazo.

Eminye imithi evame ukunikezwa ukusiza ukuvimbela i-migraine ifaka phakathi:

• imishanguzo
• ama-anticonvulsants
• imishanguzo yomfutho wegazi ophezulu, njenge-ACE inhibitors, i-beta-blockers, noma i-calcium-channel blockers
• I-CGRP inhibitors, umuthi omusha we-migraine ovimba ukuvuvukala nobuhlungu
• ubuthi be-botulinum (Botox)

Indlela yokuphila nezinketho zemvelo

Izici zokuphila nazo zingadlala indima ekuphathweni kwe-migraine. Ukucindezeleka, ikakhulukazi, kuyimbangela evamile ye-migraine. Ungase ukwazi ukunciphisa izimpawu ze-migraine ngokusebenzisa izindlela zokuphatha ukucindezeleka okunempilo, njenge:

• i-yoga
• ukuzindla
• izivivinyo zokuphefumula
• ukuphumula kwemisipha

Ukulala ngokwanele, ukudla ukudla okunempilo, nokuvivinya umzimba njalo nakho kungasiza.

Ukwelashwa okuhlanganayo kwe-migraine abanye abantu abakuthola kuwusizo kufaka phakathi:

• biofeedback
• ukutshopa
• izithako zemithi

Kodwa-ke, kudingeka olunye ucwaningo ukuthola ukuthi ngabe lezi zindlela zokwelapha ziyasebenza yini ekusizeni ukunciphisa izimpawu ze-migraine.

Okubalulekile

Ama-triptans, ama-ergotamines, ama-gepants, ama-ditans, kanye ne-NSAIDS yizindlela zokwelashwa zokuqala zokuhlaselwa okunamandla kwe-migraine. Bonke banobufakazi bemitholampilo ekusetshenzisweni kwabo.

I-Aspirin iyi-NSAID eyaziwa ngaphezu kwamakhompiyutha evame ukusetshenziselwa ukwelapha ubuhlungu obumaphakathi kuya kokulingene nokuvuvukala.

Ucwaningo luye lwabonisa ukuthi uma ithathwa ngemithamo ephezulu, i-aspirin ingasebenza ekunciphiseni ubuhlungu obunzima be-migraine. Kuthathwe ngemithamo ephansi njalo, i-aspirin ingasiza ekunciphiseni imvamisa ye-migraine, kepha ubude besikhathi kufanele kukhulunywe nodokotela wakho.

Njengemithi eminingi, i-aspirin ingaba nemiphumela emibi futhi ingahle ingaphephi kuwo wonke umuntu. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola ukuthi ngabe i-aspirin iphephile yini kuwe njengomuthi we-migraine.