Yini ukuhlolwa kweCalcitonin futhi kwenziwa kanjani

-Delile

• Yenzelwe ini
• Kwenziwa kanjani ukuhlolwa
• Uwuhlola kanjani umphumela wokuhlolwa

ICalcitonin yihomoni ekhiqizwa egilo, umsebenzi wayo ukulawula inani le-calcium elizungeza egazini, ngemiphumela efana nokuvimbela ukubuyiswa kabusha kwe-calcium emathanjeni, ukunciphisa ukumuncwa kwe-calcium ngamathumbu nokwandisa ukukhishwa izinso.

Inkomba enkulu yokuhlolwa kwe-calcitonin wukuthola uhlobo lomdlavuza wegilo obizwa nge-medullary thyroid carcinoma, othathwa njengesimpawu sesimila salesi sifo, njengoba sibangela ukuphakama okubalulekile kwaleli hormone. Ukuhlolwa kobukhona be-thyroid C-cell hyperplasia nakho okunye okukhombisa njalo, yize le hormone ingaphakanyiswa nakwezinye izimo, njengomdlavuza wamaphaphu noma webele.

Njengomuthi, ukusetshenziswa kwe-calcitonin kungaboniswa ekwelapheni izifo ezifana ne-osteoporosis, i-calcium eyeqile egazini, isifo sikaPaget noma i-reflex systematic dystrophy. Uma ufuna ukwazi kabanzi nge-calcitonin, bona ukuthi yini i-calcitonin nokuthi yenzani.

Yenzelwe ini

Isivivinyo se-calcitonin singa-odwa se:

• Ukuhlolisiswa kobukhona be-medullary thyroid carcinoma;
• Ukuphenywa kwe-hyperplasia yamaseli e-C, okungamaseli e-thyroid akhiqiza i-calcitonin;
• Ukuhlolwa kwezihlobo zeziguli ezine-medullary thyroid carcinoma, ukuthola ngokushesha isimila;
• Ukuqaphela impendulo ekwelashweni kwe-medullary thyroid carcinoma;
• Ukulandelwa komdlavuza ngemuva kokukhishwa kwe-thyroid, njengoba kulindeleke ukuthi amanani aphansi uma kwenzeka elashwa.

Yize lezi kuyizinkomba ezinkulu, kufanele kukhunjulwe ukuthi i-calcitonin nayo ingakhuphuka nakwezinye izimo, njengezinye izinhlobo zomdlavuza, njenge-leukemia, i-lung, i-pancreatic, umdlavuza webele noma we-prostate, lapho kukhona isifo esingapheliyo sezinso, ngesikhathi ukutheleleka kwamagciwane, i-hypergastrinemia, noma ngenxa ye-hyperparathyroidism hypercalcemia noma ezinye izimo.

Kwenziwa kanjani ukuhlolwa

Isikali seCalcitonin senziwa elabhoratri, ngokwesicelo sikadokotela, lapho kuthathwa khona isampula yegazi ukuthola amazinga ayisisekelo.

Amanani weCalcitonin athonyelwa yimibandela eminingana, efaka ukusetshenziswa kwemithi ethile, efana ne-Omeprazole noma i-corticosteroids, iminyaka, ukukhulelwa, ukubhema nokuphuza utshwala, ngakho-ke indlela yokwenza ukuhlolwa kuthembeke kakhudlwana ukuyenza kanye nodokotela i-calcium noma i-pentagastrin infusion test, ngaphandle kwezikhuthazi ezinamandla ze-calcitonin secretion.

Isivivinyo se-calcitonin stimulus nge-calcium infusion yiyona etholakala kakhulu, futhi yenziwa ekuseni, esiswini esingenalutho. I-calcium ifakwe ngomthambo, emizuzwini engu-0, 2, 5 no-10 ngemuva kokufakwa, ukuhlola ukuthi ngabe iphethini yokwanda ithathwa njengejwayelekile noma cha.

Uwuhlola kanjani umphumela wokuhlolwa

Amanani ajwayelekile wesethenjwa we-calcitonin angahluka ngokuya nge-laboratory ehlola. Amanani ajwayelekile yilawo angaphansi kuka-8.4 pg / ml emadodeni kanye no-5 pg / ml kwabesifazane. Ngemuva kokugqugquzela i-calcium, lawo angaphansi kwama-30 pg / ml futhi ahle uma engaphezulu kwe-100 pg / ml angathathwa njengokujwayelekile. Phakathi kuka-30 no-99 pg / dl, ukuhlolwa kubhekwa njengokungaqiniseki, futhi kufanele kwenziwe ezinye izivivinyo ukuqinisekisa lesi sifo.