I-Chloroquine: iyini, yenzelwa ini nemiphumela engemihle

-Delile

• Isetshenziswa kanjani
• 1. Umalaleveva
• 2. I-Lupus erythematosus ne-rheumatoid arthritis
• 3. I-hepatic amebiasis
• Ngabe i-chloroquine inconyelwa ukwelashwa kokutheleleka nge-coronavirus?
• Ngubani ongafanele asebenzise
• Imiphumela emibi engaba khona

IChloroquine diphosphate umuthi okhonjiswe ekwelapheni umalaleveva obangelwaIPlasmodium vivax, iPlasmodium malariae futhi IPlasmodium ovale, isibindi i-amebiasis, i-rheumatoid arthritis, i-lupus nezifo ezibangela ukuzwela kwamehlo ekukhanyeni.

Lo muthi ungathengwa ezikhemisi, lapho kwethulwa incwadi kadokotela.

Isetshenziswa kanjani

Umthamo we-chloroquine uncike kwisifo okufanele silashwe. Amaphilisi kufanele athathwe ngemuva kokudla, ukugwema isicanucanu nokuhlanza.

1. Umalaleveva

Umthamo onconyiwe ngu:

• Izingane ezineminyaka engama-4 kuya kwengu-8: ithebhulethi elilodwa ngosuku, izinsuku ezintathu;
• Izingane ezineminyaka engu-9 kuya kwengu-11 ubudala: amaphilisi ama-2 ngosuku, izinsuku ezintathu;
• Izingane ezineminyaka engu-12 kuya kwengu-14 ubudala: amaphilisi ama-3 ngosuku lokuqala, namaphilisi ama-2 ngosuku lwesibili nolwesithathu;
• Izingane ezineminyaka engaphezu kwengu-15 kanye nabantu abadala ezineminyaka engama-79 ubudala: amaphilisi ama-4 ngosuku lokuqala, namaphilisi ama-3 ngosuku lwesibili nolwesithathu;

Ukwelashwa kukamalaleveva okubangelwaP. vivax futhiP. ovale ne-chloroquine, kufanele ihlotshaniswe ne-primaquine, izinsuku ezingu-7 ezinganeni eziphakathi kweminyaka engu-4 nengu-8 nezinsuku eziyi-7 zezingane ezingaphezulu kweminyaka engu-9 kanye nabantu abadala.

Alikho inani elanele lamathebulethi e-chloroquine ezinganeni ezinesisindo somzimba esingaphansi kwe-15 kg, njengoba izincomo zokwelapha zifaka phakathi amaphilisi ama-fractional.

2. I-Lupus erythematosus ne-rheumatoid arthritis

Umthamo ophakanyisiwe ophakanyisiwe kubantu abadala ngu-4 mg / kg ngosuku, inyanga eyodwa kuya kweziyisithupha, kuya ngempendulo yokwelashwa.

3. I-hepatic amebiasis

Umthamo onconywayo kubantu abadala ngu-600 mg we-chloroquine osukwini lokuqala nolwesibili, kulandelwe u-300 mg ngosuku amasonto amabili kuya kwamathathu.

Ezinganeni, umthamo onconyiwe ngu-10 mg / kg / ngosuku lwe-chloroquine, izinsuku eziyishumi noma ngokuqonda kukadokotela.

Ngabe i-chloroquine inconyelwa ukwelashwa kokutheleleka nge-coronavirus?

I-Chloroquine ayinconywa ekwelashweni kokutheleleka nge-coronavirus entsha, njengoba kukhonjisiwe ezivivinyweni eziningi zemitholampilo ezigulini ezine-COVID-19 ukuthi lo muthi wenyuse imvamisa yemiphumela emibi kanye nokufa, futhi ayibonisanga miphumela emihle ekusetshenzisweni kwayo, okwaholela ekumisweni kokuhlolwa komtholampilo okwakwenzeka ngalo muthi.

Kodwa-ke, imiphumela yalezi zivivinyo iyahlaziywa, ukuze kuqondwe indlela nokwethembeka kwedatha.

Ngokusho kuka-Anvisa, ukuthengwa kwe-chloroquine ekhemisi kusavumelekile, kodwa kuphela kubantu abanemibhalo kadokotela engaphansi kolawulo olukhethekile, ngezinkomba ezishiwo ngenhla noma abebevele bekhombisa umuthi, ngaphambi kobhadane lwe-COVID-19.

Bona imiphumela yocwaningo olwenziwe nge-chloroquine ukwelapha i-COVID-19 nezinye izidakamizwa ezisaphenywa.

Ngubani ongafanele asebenzise

Lo muthi akufanele usetshenziswe kubantu abazwela ngokweqile kunoma yiziphi izingxenye ezikhona kwifomula, abantu abanesifo sokuwa, i-myasthenia gravis, i-psoriasis noma esinye isifo esiqothulayo.

Ngaphezu kwalokho, akumele isetshenziselwe ukwelapha umalaleveva kubantu abane-porphyria cutanea tarda futhi kufanele isetshenziswe ngokuqapha kubantu abanesifo sesibindi namathumbu, amathumbu nemithambo yegazi.

Imiphumela emibi engaba khona

Imiphumela emibi kakhulu engenzeka ngokusetshenziswa kwe-chloroquine yikhanda, isicanucanu, ukuhlanza, isifo sohudo, ubuhlungu besisu, ukulunywa, ukucasuka kanye nezimagqabhagqabha ezibomvu esikhunjeni.

Ngaphezu kwalokho, ukudideka kwengqondo, ukuquleka, ukwehla kwengcindezi yegazi, izinguquko ku-electrocardiogram nokubona okuphindiwe noma okufiphele nakho kungenzeka.