Ungayibona kanjani i-Amyloidosis

-Delile

• AL noma i-amyloidosis eyinhloko
• I-AA noma i-Amyloidosis Yesibili
• Ifa le-amyloidosis noma i-AF
• I-Senile Systemic Amyloidosis
• I-amyloidosis ehlobene nezinso
• I-Amyloidosis yasendaweni

Izimpawu ezibangelwa i-amyloidosis ziyahlukahluka kuye ngendawo esithintwa yilesi sifo, ezingadala ukushaya kwenhliziyo, ubunzima bokuphefumula nokuqina kolimi, kuya ngohlobo lwesifo umuntu anaso.

I-Amyloidosis yisifo esingajwayelekile lapho kutholakala khona amaprotheni amancane e-amyloid, okuyizintambo eziqinile ezithweni nezicubu zomzimba ezahlukahlukene, ukuvimbela ukusebenza kwawo okufanele. Lokhu kufakwa okunganele kwamaprotheni we-amyloid kungenzeka, ngokwesibonelo, enhliziyweni, isibindi, izinso, imisipha nasesimisweni sezinzwa. Bona ukuthi ungaselapha kanjani lesi sifo ngokuchofoza lapha.

Izinhlobo eziyinhloko ze-amyloidosis yilezi:

AL noma i-amyloidosis eyinhloko

Kuyindlela ejwayelekile yesifo futhi ikakhulu kubangela ushintsho kumaseli egazi. Njengoba lesi sifo siqhubeka, ezinye izitho ziyathinteka, njengezinso, inhliziyo, isibindi, ubende, izinzwa, amathumbu, isikhumba, ulimi nemithambo yegazi.

Izimpawu ezidalwa yilolu hlobo lwesifo zincike ebucayi be-amyloid, njengoba kuvamile ukungabi bikho kwezimpawu noma ukwethulwa kwezimpawu ezixhumene kuphela nenhliziyo, njengesisu esivuvukele, ukuphefumula okuncane, ukuncipha komzimba nokuquleka. Bona ezinye izimpawu lapha.

I-AA noma i-Amyloidosis Yesibili

Lolu hlobo lwesifo luvela ngenxa yokuba khona kwezifo ezingamahlalakhona noma ngenxa yesikhathi eside sokuvuvukala noma ukutheleleka emzimbeni, imvamisa isikhathi eside kunezinyanga eziyisithupha, njengasesimweni sesifo samathambo, imfiva yaseMedithera yomndeni, i-osteomyelitis, isifo sofuba, i-lupus noma amathumbu okuvuvukala isifo.

Ama-Amyloid aqala ukuhlala ezinso, kepha angathinta nesibindi, ubende, ama-lymph node namathumbu, futhi uphawu oluvame kakhulu ukuba khona kwamaprotheni emchameni, okungaholela ekuhlulekeni kwezinso nokwehla okulandelayo ukukhiqizwa komchamo nokuvuvukala komzimba.

Ifa le-amyloidosis noma i-AF

I-amyloidosis yomndeni, ebizwa nangokuthi ifa, uhlobo lwesifo oludalwa ukushintsha kwe-DNA yengane ngesikhathi sokukhulelwa noma eyazuzwa njengefa kubazali.

Lolu hlobo lwesifo luthinta kakhulu uhlelo lwezinzwa nenhliziyo, futhi izimpawu zivame ukuqala kusukela eminyakeni yobudala engama-50 noma ngesikhathi sokuguga, futhi kungahle kube nezimo lapho izimpawu zingakaze zivele futhi lesi sifo singathinti izimpilo zeziguli .

Kodwa-ke, lapho izimpawu zikhona, izici eziyinhloko ukulahlekelwa umuzwa ezandleni, isifo sohudo, ukuhamba kanzima, izinkinga zenhliziyo nezinso, kodwa uma sikhona ngezindlela ezinzima kakhulu, lesi sifo singadala ukufa kwezingane eziphakathi kweminyaka engu-7 nengu-10. .

I-Senile Systemic Amyloidosis

Lolu hlobo lwesifo luvela kubantu asebekhulile futhi luvame ukudala izinkinga zenhliziyo njengokuhluleka kwenhliziyo, ukushaya kwenhliziyo, ukukhathala okulula, ukuvuvukala emilenzeni nasemaqakaleni, ukuphefumula kancane kanye nomchamo owedlulele.

Kodwa-ke, lesi sifo sivela kancane futhi asiphazamisi ukusebenza kwenhliziyo.

I-amyloidosis ehlobene nezinso

Lolu hlobo lwe-amyloidosis lwenzeka ezigulini ezinenkinga yezinso futhi osekuphele iminyaka eminingi zisebenzisa i-hemodialysis, njengoba isihlungi somshini we-dialysis singakwazi ukuqeda iphrotheni ye-beta-2 microglobulin emzimbeni, egcina iqoqeka emalungeni nasemathanjeni.

Ngakho-ke, izimpawu ezibangelwe ubuhlungu, ukuqina, ukuqoqwa koketshezi emajoyintini kanye ne-carpal tunnel syndrome, ebangela ukuhayiza nokuvuvukala eminweni. Bona ukuthi ungaphatha kanjani iCarpal Tunnel Syndrome.

I-Amyloidosis yasendaweni

Kungaleso sikhathi lapho ama-amyloid aqoqana esifundeni esisodwa noma esithweni somzimba, okudala izicubu ikakhulu esinyeni nasendleleni yomoya, njengamaphaphu ne-bronchi.

Ngaphezu kwalokho, izicubu ezibangelwa yilesi sifo nazo zinganqwabelana esikhunjeni, emathunjini, esweni, esonweni, emphinjeni nasolimini, zivame kakhulu ezimweni zohlobo lwesifo sikashukela sohlobo 2, umdlavuza wegilo nasemva kweminyaka engama-80 ubudala.