Umlobi: Judy Howell
Usuku Lokudalwa: 5 Ujulayi 2021
Ukuvuselela Usuku: 16 Unovemba 2024
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-Delile

Ezigidini zabantu baseMelika abathintekayo yi-fibromyalgia, imishanguzo inikela ngethemba lokwelapha lesi simo esibuhlungu ngokuhlanganyela kanye nasemisipha nokukhathala.

ICymbalta (duloxetine) ivunywa yi-Food and Drug Administration yokuphathwa kwe-fibromyalgia kubantu abadala. Funda ukuze uthole ukuthi ngabe iCymbalta ingakulungela yini.

Kuyini iCymbalta?

ICymbalta ingeyesigaba semithi esibizwa ngeSNRIs (serotonin-norepinephrine reuptake inhibitors) esivimba ukubuyiselwa kwe-neurotransmitters norepinephrine ne-serotonin ebuchosheni.

Ngaphambi kokuvunyelwa i-fibromyalgia, ivunyelwe ukwelashwa kwe:

  • ukukhathazeka ngokweqile (GAD)
  • ukucindezeleka okukhulu (MDD)
  • ubuhlungu besifo sikashukela besifo sikashukela (DPNP)
  • ubuhlungu obungapheli besisipha

Isebenza kanjani iCymbalta

Yize kungaziwa imbangela ngqo ye-fibromyalgia, abacwaningi basikisela ukuthi ubuchopho babantu abane-fibromyalgia buyashintshwa ngokuvuselelwa kwezinzwa okuphindaphindwayo. Okubandakanyeka kulolo shintsho kungaba ukwanda okungajwayelekile kwama-neurotransmitters athile (amakhemikhali akhombisa ubuhlungu).


Futhi, kuphakanyiswa ukuthi ama-receptors wezinhlungu ebuchosheni azwela kakhulu futhi angasabela ngokweqile kwizimpawu zobuhlungu.

ICymbalta inyusa inani le-serotonin ne-norepinephrine ebuchosheni. Lawa makhemikhali asiza ukugcina ukulinganisela kwengqondo futhi amise ukuhamba kwezimpawu zobuhlungu ebuchosheni.

Yimiphi imiphumela emibi yeCymbalta?

ICymbalta ihlotshaniswa nemiphumela emibi eminingi engaba khona. Abaningi abadingi ukunakekelwa kwezokwelapha kufaka phakathi:

  • izinguquko zokudla
  • ukungaboni kahle
  • umlomo owomile
  • ikhanda
  • ukujuluka okwandayo
  • isicanucanu

Imiphumela emibi yokwazisa udokotela wakho ngokushesha kufaka phakathi:

  • ukuvuvukala kwesisu
  • ukuyaluza
  • ukusabela okweqile njengokulunywa, ukuqubuka noma isifuba, ukuvuvukala kobuso, izindebe, ubuso noma ulimi
  • umfutho wegazi uyashintsha
  • amabhamuza noma isikhumba esikhanyayo
  • ukudideka
  • umchamo omnyama
  • isifo sohudo
  • imfiva
  • izimpawu ezinjengomkhuhlane
  • ukushaqeka
  • ukushaya kwenhliziyo okungajwayelekile kanye / noma okusheshayo
  • ukulahlekelwa ibhalansi kanye / noma isiyezi
  • ukulahlekelwa ukuxhumana neqiniso, ukusangana
  • ukuguquka kwemizwelo
  • isithuthwane
  • imicabango yokuzibulala
  • ukulimaza noma ukopha okungavamile
  • ukuhlanza
  • ukuncipha komzimba

Imiphumela emibi yezocansi neCymbalta

Ama-SNRIs aziwa ngokudala imiphumela emibi yezocansi. Ngakho-ke, iCymbalta ingadala imiphumela emibi yezocansi, njengezinkinga nge:


  • ukuvusa inkanuko
  • induduzo
  • ukwaneliseka

Ngenkathi imiphumela emibi yezocansi iyinkinga kwabanye abantu, kwabaningi incane noma ilinganisela njengoba imizimba yabo ivumelana nomuthi. Ukwehlukaniswa kwale miphumela emibi nakho kungancika ezingeni lomthamo.

Imithi engasebenzisana neCymbalta

Ngokusho kweNational Alliance on Mental Illness (NAMI), i-duloxetine (Cymbalta) akufanele ithathwe noma kungakapheli amasonto amabili kuthathwe i-monoamine oxidase inhibitors (MAOIs) efana ne:

  • i-tranylcypromine (iParnate)
  • i-selegiline (Emsam)
  • i-rasagiline (Azilect)
  • i-phenelzine (Nardil)
  • isocarboxazid (Marplan)

I-NAMI ibuye ikhombise ukuthi kungakhuphula imiphumela yemithi ethile engadala ukopha njenge:

  • i-aspirin
  • ibuprofen (Advil, Motrin)
  • i-warfarin (i-Coumadin)

I-NAMI iphinde ikhombise ukuthi amazinga kanye nemiphumela yeCymbalta ingahle inyuswe ngeminye imithi kubandakanya:

  • i-cimetidine (Tagamet)
  • i-ciprofloxacin (Cipro)
  • i-fluoxetine (Prozac)
  • i-fluvoxamine (Luvox)
  • i-paroxetine (Paxil)

Kubalulekile ukuthi udokotela wakho ayazi yonke eminye imithi oyisebenzisayo. Odokotela bayalwazi lolu hlu olungenhla kanye neminye imithi ejwayele ukusebenzisana neCymbalta. Bazokwenza izinqumo mayelana nokugwema noma ukulungiswa kwesilinganiso lapho kufanele khona.


Yini enye okufanele ngiyazi ngeCymbalta?

Misa kuphela ukuthatha iCymbalta ngokuvunyelwa udokotela. Imithamo elahlekile inamandla okwandisa ubungozi bakho bokuphinda ubuye ezimpawu zakho.

Lapho usukulungele ukuyeka ukuthatha iCymbalta, khuluma nodokotela wakho ngokukwenza kancane kancane. Ukuma ngokuzumayo kungahle kube nezimpawu zokuhoxa njenge:

  • isiyezi
  • ikhanda
  • ukucasuka
  • isicanucanu
  • amaphupho amabi
  • i-paresthesias (ukubhoboza, ukuhlabana, ukuzwa kwesikhumba)
  • ukuhlanza

Kungenzeka udokotela wakho azokwazi ukukusiza unciphise izimpawu zokuhoxa.

Ngenkathi uthatha iCymbalta uzophinde ufune ukugwema ukuphuza utshwala noma ukusebenzisa kabi izinto ezifana nama-opioid. Hhayi nje ukuthi bangehlise izinzuzo ezilethwa yiCymbalta, kepha bangakhuphula nobukhulu bemiphumela emibi.

Futhi, ukuphuza utshwala kungakhuphula ubungozi bezinkinga zesibindi ngenkathi kuthathwa iCymbalta ngasikhathi sinye.

Ezinye izindlela zeCymbalta zokwelapha i-fibromyalgia

Enye i-SNRI evunyelwe ukwelapha i-fibromyalgia yiSavella (milnacipran). Futhi kuvunyelwe yiLyrica (pregabalin), umuthi wesifo sokuwa nesifo sezinzwa.

Udokotela wakho futhi angancoma:

  • Ukudambisa izinhlungu ezithengelwe njenge-acetaminophen (iTylenol) ne-ibuprofen (Advil, Motrin)
  • Ukudambisa izinhlungu kadokotela njenge-tramadol (Ultram)
  • imishanguzo yokulwa nokubanjwa njenge-gabapentin (Neurontin)

Ukudla okudlela endlini

Kokubili ngokomzimba nangokomzwelo, i-fibromyalgia ingaba yisimo esinzima ukuhlala nayo. Imithi efana neCymbalta isebenze ekwelapheni izimpawu eziningi zalesi sifo esingelapheki futhi esivame ukukhubaza.

Uma udokotela wakho encoma iCymbalta, babuze imibuzo ngemiphumela yayo emihle ekwelapheni izimpawu zakho, kanye nemiphumela emibi engaba khona. Xoxa ngesenzo sakho uma unemiphumela emibi.

Ngaso sonke isikhathi qiniseka ukuthi unikeza udokotela wakho lonke ulwazi mayelana neminye imithi nezithasiselo ozithathayo.

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