Ukuhlolwa kwama-anti-HBs: kwenzelwa ini nokuthi uwuqonde kanjani umphumela

-Delile

• Yenzelwe ini
• Ukuhlolwa kwe-HBsAg
• Kwenziwa kanjani
• Ukuqonda imiphumela

Ukuhlolwa kwe-anti-hbs kuyacelwa ukuthi kubhekwe ukuthi ngabe umuntu akanalo yini igciwane lesifo sokusha kwesibindi kohlobo B, ukuthi ulitholile ngokugoma noma ngokuselapha lesi sifo.

Lokhu kuhlolwa kwenziwa ngokuhlaziya isampula legazi elincane lapho inani lama-antibodies alwa negciwane le-hepatitis B lihlolwa egazini.Ngokujwayelekile, ukuhlolwa kwe-anti-hbs kuyacelwa kanye nokuhlolwa kwe-HBsAg, okuwukuhlolwa lapho igciwane likhona egazini ngakho-ke isetshenziselwa ukuxilonga.

Yenzelwe ini

Ukuhlolwa kwama-anti-hbs kusetshenziselwa ukuhlola ukukhiqizwa komzimba kwama-antibodies ngokumelene neprotheni ekhona ebusweni begciwane le-hepatitis B, i-HBsAg. Ngakho-ke, ngokuhlolwa kwe-anti-hbs, udokotela angabheka ukuthi ngabe umuntu ugonyelwe i-hepatitis B noma cha, ngokugoma, ngaphezu kokubheka ukuthi ngabe ukwelashwa kuyasebenza yini noma sekuphulukisiwe, lapho kutholakala ukuthi i-hepatitis B yaqinisekiswa.

Ukuhlolwa kwe-HBsAg

Ngenkathi kucelwa ukuhlolwa kwe-anti-hbs ukuze kuqinisekiswe ukungavikeleki kanye nokuphendula ekwelashweni, ukuhlolwa kwe-HBsAg kuyacelwa ngudokotela ukuthola ukuthi ngabe umuntu uthelelekile noma uke waxhumana negciwane lesifo sokusha kwesibindi kohlobo B. ukuhlolwa kucelwa ukuxilonga isifo sokusha kwesibindi B.

I-HBsAg yiprotheni ekhona ebusweni begciwane le-hepatitis B futhi ilusizo ekuhloleni i-hepatitis B. Imvamisa ukuhlolwa kwe-HBsAg kuyacelwa kanye ne-anti-hbs test, ngoba kungenzeka ukubheka ukuthi ngabe igciwane liyazungeza yini egazini nokuthi umzimba usebenza ngalo. Lapho umuntu enesifo sokusha kwesibindi kohlobo B, lo mbiko uqukethe i-reagent HBsAg, okuwumphumela obalulekile kudokotela, ngoba lena yindlela yokuqala ukwelashwa. Qonda ukuthi i-hepatitis B iphathwa kanjani.

Kwenziwa kanjani

Ukwenza ukuhlolwa kwama-anti-hbs, akukho ukulungiselela noma ukuzila ukudla okudingekayo futhi kwenziwa ngokuqoqa isampula legazi elincane, elithunyelwa elabhorethri liyohlaziywa.

Egumbini lokucwaninga, igazi lenza inqubo yokuhlaziya i-serological, lapho kutholakala khona ukutholakala kwamasosha omzimba athile alwa negciwane le-hepatitis B. Lawa masosha omzimba akhiwa ngemuva kokuhlangana naleli gciwane noma ngenxa yokugoma, lapho umzimba uvuselelwa khona akhiqize la masosha omzimba, anikeze ukuvikeleka kumuntu impilo yakhe yonke.

Yazi ukuthi umuthi wokugoma i-hepatitis B kufanele uthathwe nini.

Ukuqonda imiphumela

Umphumela wokuhlolwa kwama-anti-hbs uyehluka ngokuya ngokuxinana kwamasosha omzimba alwa negciwane le-hepatitis B egazini, ngamanani ayizethenjwa athi:

• Ukuhlushwa kwama-anti-hbs ngaphansi kuka I-10 mUI / mL - engeyona reagent. Lokhu kuhlanganiswa kwamasosha omzimba akwanele ukuvikela kulesi sifo, kubalulekile ukuthi umuntu agonyelwe igciwane. Uma kwenzeka kutholakala ukuthi kunesifo sokusha kwesibindi kohlobo B esivele senziwe, lokhu kuhlushwa kukhombisa ukuthi belingekho ikhambi nokuthi ukwelashwa akusebenzi noma kusesigabeni sokuqala;
• Ukugxila kwama-anti-hbs phakathi kuka-10 mUI / mL no-100 mUI / mL - akuqedi noma kuyenelisa ukugoma. Lokhu kuhlanganiswa kungakhombisa ukuthi umuntu ugonyelwe igciwane le-hepatitis B noma uyelashwa, futhi akunakwenzeka ukuthola ukuthi ngabe i-hepatitis B yelaphiwe yini. Kulezi zimo, kunconywa ukuthi ukuhlolwa kuphindwe ngemuva kwenyanga e-1;
• Ukugxila kwama-anti-hbs okukhulu kune-100 mIU / mL - reagent. Lokhu kuhlushwa kukhombisa ukuthi umuntu unamasosha omzimba ngokumelene negciwane le-hepatitis B, kungaba ngokugoma noma ngokwelapha lesi sifo.

Ngaphezu kokuhlola imiphumela yokuhlolwa kwama-anti-hbs, udokotela uphinde ahlaziye umphumela wokuhlolwa kwe-HBsAg. Ngakho-ke, lapho kuqashwa umuntu osevele etholakale enesifo sokusha kwesibindi kohlobo B, umphumela omuhle we-HBsAg non-reactive kanye ne-anti-hbs ukhombisa ukuthi lowo muntu welaphekile nokuthi awekho amagciwane ajikeleza egazini. Umuntu ongenaso isifo sokusha kwesibindi kohlobo B naye unemiphumela efanayo nokuhlushwa kwama-anti-hbs okungaphezu kwe-100 mIU / mL.

Endabeni ye-HBsAg kanye nama-anti-hbs amahle, kunconywa ukuphinda isivivinyo ngemuva kwezinsuku eziyi-15 kuya kwezingama-30, ngoba kungakhombisa umphumela omuhle ongamanga, ukwakheka kwama-immune complexes (ama-immune complexes) noma ukutheleleka ngama-subtypes ahlukahlukene we-hepatitis B igciwane.