Umlobi: John Stephens
Usuku Lokudalwa: 26 Ujanuwari 2021
Ukuvuselela Usuku: 15 Ufebhuwari 2025
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What You Need To Know About Glatiramer Acetate (Copaxone®, Glatopa™)
Ividiyo: What You Need To Know About Glatiramer Acetate (Copaxone®, Glatopa™)

-Delile

Yini iCopaxone?

I-Copaxone ngumuthi kadokotela obizwa ngegama lomkhiqizo. Kuvunyelwe ukwelapha izinhlobo ezithile ze-multiple sclerosis (MS) kubantu abadala.

Nge-MS, amasosha akho omzimba ahlasela ngephutha izinzwa zakho. Izinzwa ezilimele bese zinenkinga yokuxhumana nobuchopho bakho. Lesi simo singadala izimpawu ezahlukahlukene, njengobuthakathaka bemisipha nokukhathala (ukungabi namandla).

Ngokuqondile, iCopaxone ingasetshenziselwa ukwelapha lezi zimo ezilandelayo:

  • I-Clinic isolated syndrome (i-CIS). Nge-CIS, unesiqephu sezimpawu ezifana ne-MS ezihlala okungenani amahora angama-24. I-CIS kungenzeka noma ingakhuli ibe yi-MS.
  • Ukubuyisela kabusha i-MS (RRMS). Ngaleli fomu le-MS, unezikhathi lapho izimpawu zakho ze-MS ziphinda zivele (zivuleka) zilandelwa yizikhathi lapho izimpawu zakho ze-MS zikhululiwe (zithuthukisiwe noma sezihambile).
  • Kuyasebenza i-MS yesibili eqhubekayo. Ngaleli fomu le-MS, isimo siya ngokuya siba sibi, kepha usenezikhathi zokubuyela emuva. Ngesikhathi sokubuyela emuva, izimpawu zakho ziba zimbi kakhulu isikhashana.

Imininingwane

I-Copaxone iqukethe i-acetate yesidakamizwa esisebenzayo i-glatiramer. Kuyindlela yokwelapha eguqula izifo ye-MS. ICopaxone isiza ukumisa amasosha omzimba wakho ekuhlaseleni izinzwa zakho. Isidakamizwa singanciphisa inani lokuphindaphinda kwe-MS onayo futhi sinciphise nokuwohloka kwesifo sakho.


ICopaxone iza njengesisombululo esinikezwa ngomjovo ongaphansi (umjovo ngaphansi kwesikhumba sakho). Umhlinzeki wakho wezokunakekelwa kwempilo uzokukhombisa wena noma umnakekeli wakho ukuthi ungasisebenzisa kanjani lesi sidakamizwa.

ICopaxone iza ngomthamo owodwa, imijovo ekhethiwe. Itholakala ngamandla amabili: 20 mg no-40 mg. Umjovo we-20-mg uthathwa kanye ngosuku, kanti umjovo we-40-mg uthathwa kathathu ngesonto okungenani amahora angama-48 ngaphandle.

Ukusebenza ngempumelelo

Ngemininingwane mayelana nokusebenza kweCopaxone, bheka isigaba "Copaxone for MS" ngezansi.

ICopaxone ejwayelekile

I-Copaxone iqukethe i-acetate yesidakamizwa esisebenzayo i-glatiramer. Izinhlobo ezijwayelekile zeCopaxone ziyatholakala, kufaka phakathi umuthi ojwayelekile obizwa ngeGlatopa.

Umuthi ojwayelekile ikhophi eliqondile lomuthi osebenzayo emithini enegama lomkhiqizo. Okujwayelekile kuthathwa njengokuphephile nokusebenza ngempumelelo njengomuthi wokuqala. Imvelo ejwayelekile ijwayele ukubiza ngaphansi kwezidakamizwa ezinamagama.

Imiphumela emibi yeCopaxone

I-Copaxone ingadala imiphumela emibi noma emibi. Uhlu olulandelayo luqukethe eminye yemiphumela emibi engase ivele ngenkathi uthatha iCopaxone. Lezi zinhlu azibandakanyi yonke imiphumela emibi engaba khona.


Ukuthola eminye imininingwane ngemiphumela engemihle yeCopaxone, khuluma nodokotela wakho noma usokhemisi. Bangakunika amathiphu okuthi ungabhekana kanjani nanoma yimiphi imiphumela emibi engase ikukhathaze.

Qaphela: Ukuphathwa Kwezokudla Nezidakamizwa (i-FDA) kulandelela imiphumela emibi yezidakamizwa eyivumile. Uma ungathanda ukubika kwi-FDA imiphumela eseceleni oye waba nayo ngeCopaxone, ungakwenza lokho ngeMedWatch.

Ihlala isikhathi esingakanani imiphumela emibi yeCopaxone?

Imiphumela emibi ongaba nayo evela kwiCopaxone, nokuthi ihlala isikhathi esingakanani, kuncike ekutheni umzimba wakho uphendula kanjani kumuthi.

Eminye imiphumela emibi ingahlala isikhashana nje. Isibonelo, abanye abantu banokuphendula okubizwa nge- postinjection reaction ngemuva nje kokuthola umjovo weCopaxone. Lo mphumela ohlangothini ungadala izimpawu ezinjengokuhlanza, ubuhlungu besifuba, nokushaya kwenhliziyo okusheshayo. Uma une-postinjection reaction ku-Copaxone, izimpawu zakho zingahlala kuze kufike ehoreni elilodwa ngemuva kokuthatha umthamo wakho.

Ngakolunye uhlangothi, eminye imiphumela emibi ingahlala isikhathi eside. Isibonelo, abanye abantu banokulimala kwesikhumba lapho bajova khona iCopaxone esikhunjeni sabo. Futhi kwezinye izimo, ukulimala kwesikhumba okubangelwa imijovo yeCopaxone kungaba unomphela. (Ukusiza ukunciphisa ingozi yokulimala kwesikhumba, kufanele ujikeleze amasayithi wokujova lapho uthatha umjovo wakho ngamunye weCopaxone.)


Ukuze ufunde kabanzi ngalunye lwalemiphumela emibi, bona isigaba esithi “Imininingwane yomthelela oseceleni” ngezansi.

Imiphumela emibi emincane

Imiphumela emibi ye-Copaxone ingafaka:

  • ukuphendula kwesiza somjovo, okungadala ububomvu, ubuhlungu, ukulunywa, izigaxa, noma ukuvuvukala endaweni yomjovo wakho
  • ukuqhuma
  • ukuqubuka kwesikhumba
  • ukuphelelwa umoya
  • ukukhathazeka
  • isicanucanu nokuhlanza
  • ubuthakathaka
  • izifo, njengomkhuhlane ovamile noma umkhuhlane
  • ubuhlungu emhlane wakho noma kwezinye izitho zomzimba wakho
  • ukushaya kwenhliziyo (uzizwe sengathi inhliziyo yakho iyagijima, ishaya, noma ishaya ngamandla)
  • ajuluke ngaphezu kokujwayelekile
  • ukushintsha kwesisindo, kufaka phakathi ukuzuza kwesisindo noma ukwehla kwesisindo

Iningi lalemiphumela emibi ingahle ihambe ezinsukwini ezimbalwa noma emasontweni ambalwa. Kepha uma ziba nzima kakhulu noma zingahambi, khuluma nodokotela wakho noma usokhemisi.

Imiphumela emibi kakhulu

Imiphumela emibi ebucayi evela kuCopaxone ayijwayelekile, kepha ingenzeka. Shayela udokotela wakho ngokushesha uma unemiphumela emibi kakhulu. Kodwa shayela ku-911 uma izimpawu zakho zizizwa zisongela impilo noma uma ucabanga ukuthi unezimo eziphuthumayo zezokwelapha.

Imiphumela emibi ebucayi, echazwe ngokuningiliziwe ngezansi ku- “Side effect imininingwane,” ifaka:

  • ukusabela kwe-postinjection (ukusabela okwenzeka ngaphakathi komzimba wakho ngemuva nje kokuthola umjovo wezidakamizwa)
  • ukulimala kwesikhumba endaweni yomjovo wakho
  • ubuhlungu besifuba
  • ukusabela okweqile

Imininingwane yomphumela oseceleni

Ungase uzibuze ukuthi kaningi kangakanani imiphumela emibi ethile eba khona ngalo muthi. Nayi imininingwane ngeminye imiphumela emibi engadalwa yilesi sidakamizwa.

Ukusabela kwe-Postinjection

Abanye abantu baphendula ngeCopaxone ngemuva nje kokuthola umjovo womuthi. Lo mphumela oseceleni ubizwa ngokuthi yi-postinjection reaction. Kungadala izimpawu kufaka phakathi:

  • ukuqhuma
  • ubuhlungu besifuba
  • ukushaya kwenhliziyo okusheshayo
  • ukushaya kwenhliziyo (uzizwe sengathi inhliziyo yakho iyagijima, ishaya, noma ishaya ngamandla)
  • inkinga yokuphefumula
  • ukuqina emphinjeni wakho
  • ukukhathazeka
  • i-urticaria (isifuba esilumayo)

Izimpawu zokuphendula kwe-postinjection zivame ukuthuthuka kungakapheli ihora eli-1 ngemuva komjovo wakho. Uma izimpawu zakho zihlala isikhathi eside kunalezi, noma zinzima, shayela udokotela wakho ngokushesha. Kepha uma izimpawu zakho zizwa zisongela impilo, shayela u-911.

Abanye abantu bane-postinjection reaction ngemuva komjovo wabo wokuqala weCopaxone. Kepha abanye abantu bangaphendula ngemuva kokujova ngakunye komuthi. Kungenzeka futhi ukuthi uqale ube nalokhu kusabela ngemuva kokuthi uthole imijovo yeCopaxone esikhathini esedlule ngaphandle kwezinkinga.

Uma ukhathazekile ngokuba ne-postinjection reaction nge-Copaxone, khuluma nodokotela wakho.

Kuvame kangakanani ukusabela kwe-postinjection?

Ezifundweni zokwelashwa, cishe i-16% yabantu abathathe i-Copaxone 20 mg nsuku zonke babenokuphendula kwe-postinjection. Ngokuqhathanisa, u-4% wabantu abathathe i-placebo (asikho isidakamizwa esisebenzayo) babenokuphendula kwe-postinjection.

Ukuphendula komjovo weposi bekungajwayelekile kubantu abathathe iCopaxone 40 mg kathathu ngesonto. Isibonelo, ngesikhathi socwaningo lomtholampilo, u-2% walaba bantu wayenokuphendula kwe-postinjection. Kulesi sifundo esithile, akekho noyedwa othatha i-placebo onokuphendula kwe-postinjection.

Izigaxa zesayithi lokujova noma ubuhlungu

Imiphumela emibi kakhulu yeCopaxone ukusabela kwesikhumba okwenzeka ezindaweni zokujova. Lokhu kusabela kungadala ukulimala, ububomvu, ukuvuvukala, izigaxa, ubuhlungu, noma ukulunywa.

Ezifundweni zomtholampilo, kubikwe ukusabela okulandelayo kwendawo yokujova:

  • Ububomvu. Lo mphumela ohlangothini uvele kuma-22% kuya kuma-43% wabantu abathathe iCopaxone. Uma kuqhathaniswa, u-2% kuya ku-10% wabantu abathathe i-placebo (asikho isidakamizwa esisebenzayo) ababebomvu.
  • Ubuhlungu. Lo mphumela ohlangothini uvele kubantu abangu-10% kuya ku-40% abathathe iCopaxone. Uma kuqhathaniswa, u-2% kuya ku-20% wabantu abathathe i-placebo babenobuhlungu.
  • Ukulunywa. Lo mphumela ohlangothini uvele kubantu abangu-6% kuya ku-27% abathathe iCopaxone. Uma kuqhathaniswa, u-0% kuya ku-4% wabantu abathathe i-placebo babenokunwaya.
  • Izigaxa. Lo mphumela ohlangothini uvele kubantu abangu-6% kuya ku-26% abathathe iCopaxone. Uma kuqhathaniswa, u-0% kuya ku-6% wabantu abathathe i-placebo babenezigaxa.
  • Ukuvuvukala. Lo mphumela ohlangothini uvele kubantu abangu-6% kuya ku-19% abathathe iCopaxone. Uma kuqhathaniswa, u-0% kuya ku-4% wabantu abathathe i-placebo babe nokuvuvukala.

Phakathi nezifundo, ukusabela kwendawo yokujova kwakuvame kakhulu kubantu abathatha iCopaxone 20 mg nsuku zonke kunabantu ababethatha iCopaxone 40 mg kathathu ngesonto.

Uma une-reaction site yomjovo ku-Copaxone, ukuphendula kufanele kunciphise ezinsukwini ezimbalwa. Kodwa uma kungenjalo noma izimpawu zakho zinzima, shayela udokotela wakho.

Ukulimala kwesikhumba endaweni yomjovo

Imvamisa, imijovo yeCopaxone ingadala ukulimala kwesikhumba endaweni yemijovo yakho. Kwezinye izimo, ukulimala kwesikhumba okubangelwa imijovo yeCopaxone kungaba unomphela.

Izibonelo zokulimala kwesikhumba okungenzeka ngeCopaxone zifaka:

  • I-Lipoatrophy. Nge-lipoatrophy, ungqimba olunamafutha ngaphansi kwesikhumba sakho lulimele. Lo monakalo ungadala imigodi ehlala njalo esikhunjeni sakho. Ezifundweni zokwelashwa, i-lipoatrophy yenzeka kubantu abangu-2% abathatha iCopaxone 20 mg nsuku zonke. Futhi kwenzeka kubantu abangu-0.5% abathathe iCopaxone 40 mg kathathu ngesonto. Akekho owathatha i-placebo (asikho isidakamizwa esisebenzayo) owayene-lipoatrophy.
  • Isikhumba necrosis. Nge-necrosis yesikhumba, amanye amangqamuzana akho esikhumba ayafa. Lesi simo singadala ukuthi izindawo zesikhumba sakho zibukeke zinsundu noma zimnyama. Lokhu kungumphumela wecala ongajwayelekile obikwe kuphela kusukela iCopaxone ikhishelwe emakethe. Futhi akwaziwa kahle ukuthi isimo senzeka kangaki kubantu abasebenzisa iCopaxone.

Unganciphisa ubungozi bakho kokubili i-lipoatrophy ne-necrosis yesikhumba ngokulandela ngokucophelela imiyalo yomhlinzeki wakho wezokunakekelwa kwempilo ngemijovo yeCopaxone. Isibonelo, kubalulekile ukuthi ungafaki imithamo yakho endaweni efanayo emzimbeni wakho ngomthamo ngamunye. Esikhundleni salokho, kufanele ujikeleze amasayithi wakho wokujova isikhathi ngasinye lapho uthatha umthamo weCopaxone.

Uma unokukhathazeka ngokulimala kwesikhumba ngenkathi usebenzisa iCopaxone, khuluma nodokotela wakho.

Ubuhlungu besifuba

Kungenzeka ukuba nobuhlungu besifuba njengengxenye yokuphendula kwe-postinjection kuCopaxone. Ngokuphendula nge-postinjection, unezimpawu ezithile, ezifana nobuhlungu besifuba, ngemuva nje kokuthatha umthamo weCopaxone. (Bheka isigaba esingenhla ukuze uthole imininingwane ngokusabela kwe-postinjection.)

Kodwa-ke, abanye abantu abathatha iCopaxone banobuhlungu besifuba obungenzeki ngemuva kokuthola umjovo womuthi. Futhi ubuhlungu besifuba kulandela imijovo yeCopaxone abuhlali bukhona ngezinye izimpawu.

Ezifundweni zokwelashwa, cishe i-13% yabantu abathathe i-Copaxone 20 mg nsuku zonke babenobuhlungu besifuba. Futhi cishe abantu abangu-2% abathathe iCopaxone 40 mg kathathu ngesonto babenobuhlungu besifuba. Uma kuqhathaniswa, kubikwa ubuhlungu besifuba ku-1% kuya ku-6% wabantu abathathe i-placebo (asikho isidakamizwa esisebenzayo). Ezifundweni, obunye lobu buhlungu besifuba buhlobene nokusabela kwe-postinjection. Kodwa ezimweni eziningi, bekungahlobene nokusabela kwe-postinjection.

Uma unezinhlungu esifubeni ngenkathi uthatha iCopaxone, kufanele ihambe ngokushesha. Kodwa-ke, uma unezinhlungu ezihlala isikhathi eside kunemizuzu embalwa noma zinzima, shayela udokotela wakho ngendlela efanele. Futhi uma ubuhlungu bakho buzwa impilo yakho isongela, shayela ku-911.

Ukusabela okweqile

Njengezidakamizwa eziningi, abanye abantu bangaba nokungezwani komzimba ngemuva kokuthatha iCopaxone. Kepha akwaziwa ukuthi ukusabela okweqile komzimba kwenzeka kangaki kubantu abasebenzisa lo muthi.

Izimpawu zokuphendula okuncane komzimba zingabandakanya:

  • ukuqubuka kwesikhumba
  • ukulunywa
  • ukuqhuma (ukufudumala nokubomvu esikhunjeni sakho)

Ukusabela okweqile okwedlulele akuvamile kodwa kungenzeka. Izimpawu zokuphendula okweqile kakhulu zingabandakanya:

  • ukuvuvukala ngaphansi kwesikhumba sakho, imvamisa ezinkalweni zakho, izindebe, izandla, noma izinyawo
  • ukuvuvukala kolimi lwakho, umlomo, noma umphimbo
  • inkinga yokuphefumula

Shayela udokotela wakho ngokushesha uma une-reaction engathí sina ye-Copaxone. Kodwa shayela ku-911 uma izimpawu zakho zizizwa zisongela impilo noma uma ucabanga ukuthi unezimo eziphuthumayo zezokwelapha.

Ukuzuza kwesisindo noma ukunciphisa umzimba

Abanye abantu abathatha iCopaxone bathole isisindo. Ezifundweni zomtholampilo, abantu abangu-3% abathathe lesi sidakamizwa baba nesisindo. Uma kuqhathaniswa, i-1% yabantu abathathe i-placebo (asikho isidakamizwa esisebenzayo) esikhuluphele.

Kodwa-ke, ukuzuza kwesisindo kungabuye kuhlotshaniswe ne-multiple sclerosis (MS) uqobo. Isibonelo, izimpawu ezimbili ezivame kakhulu ze-MS ukukhathala (ukungabi namandla) nenkinga yokuhamba. Futhi zombili lezi zimpawu zingakwenza ungasebenzi ngokweqile kunokujwayelekile, okungaholela ekutholeni isisindo.

Kubalulekile futhi ukuqaphela ukuthi ama-corticosteroids, asetshenziselwa ukwelapha ukuqhuma kwezimpawu ze-MS, nawo angadala ukuzuza kwesisindo.

Ngakolunye uhlangothi, kuye kwaba neminye imibiko yokwehla kwesisindo kubantu abasebenzisa iCopaxone. Noma kunjalo, le mibiko yayingavamile. Akwaziwa ukuthi ukwehla kwesisindo kwenzeka kaningi kangakanani kubantu abasebenzisa iCopaxone, noma uma imiphumela emibi ibangelwa yiCopaxone.

Uma ukhathazekile ngoshintsho kusisindo sakho ngenkathi uthatha iCopaxone, khuluma nodokotela wakho. Bangancoma amathiphu wokudla nokuvivinya umzimba ukukusiza ukuphatha isisindo somzimba esinempilo kuwe.

Ukucindezeleka

Abanye abantu bangaba nokudangala ngenkathi bethatha iCopaxone. Ezifundweni, abanye abantu abathatha iCopaxone babike ukuthi banokudangala. Kodwa-ke, akwaziwa ukuthi lo mphumela wecala wenzeke kaningi kangakanani, noma uma ubangelwa yiCopaxone.

Kodwa-ke, ucwaningo lwakamuva luthole ukuthi iCopaxone ayikhuphuli ubungozi bokucindezeleka kubantu abane-MS. Futhi olunye ucwaningo lukhombisile ukuthi iCopaxone ayizenzakalisanga izimpawu zokucindezeleka kubantu asebevele benaso lesi sifo.

Kubalulekile ukuqaphela ukuthi ukucindezeleka kuvamile kubantu abane-multiple sclerosis (MS). Isibonelo, ukucindezeleka kwenzeka kubantu abangaba ngu-40% kuya ku-60% abane-MS ngesikhathi esithile ngesikhathi sokuphila kwabo.

Uma uzizwa ucindezelekile ngenkathi uthatha iCopaxone, khuluma nodokotela wakho. Kunezindlela eziningi zokwelashwa ezisebenzayo ezingakusiza ukuphatha lesi sifo. Futhi udokotela wakho angancoma ukuthi yiziphi izindlela zokwelashwa ezingcono kakhulu kuwe.

Ukulahleka kwezinwele (hhayi umphumela ohlangothini)

Ukulahleka kwezinwele akubonwanga kubantu abathathe iCopaxone ngesikhathi sokuqala kwezifundo zokwelashwa.

Kodwa-ke, ukulahleka kwezinwele kungumphumela ojwayelekile wezidakamizwa ze-immunosuppressant, kwesinye isikhathi ezisetshenziselwa ukwelapha i-multiple sclerosis (MS). Le mithi ifaka i-mitoxantrone ne-cyclophosphamide. Kodwa khumbula ukuthi iCopaxone ayisona isidakamizwa sokuzivikela.

Uma ukhathazekile ngokulahleka kwezinwele ngenkathi uthatha iCopaxone, khuluma nodokotela wakho. Bangakusiza uthole izindlela zokuphatha lo mphumela oseceleni.

Ungayithatha kanjani iCopaxone

Kufanele uthathe i-Copaxone ngokwemiyalo kadokotela wakho noma yomhlinzeki wezokunakekelwa kwempilo.

I-Copaxone ithathwa ngomjovo ongaphansi (umjovo ngaphansi kwesikhumba sakho). Umhlinzeki wakho wezokunakekelwa kwezempilo uzokufundisa noma anakekele umhlinzeki wakho ukuthi ungasisebenzisa kanjani lesi sidakamizwa. Futhi lapho usaqala ukwelashwa kweCopaxone, udokotela noma umhlengikazi wakho uzokusiza ukukunika umjovo wakho wokuqala.

ICopaxone iza njengesisombululo ngaphakathi komthamo owodwa, imijovo ekhethiwe enenaliti enamathiselwe. Uma ungakhululekile ukusebenzisa le mijovo, buza udokotela wakho ngedivayisi ekhethekile, ebizwa nge- okuzenzakalelayoject 2 ngesirinji yesilazi.

Ukuze usebenzise i okuzenzakalelayoject 2, uzofaka isirinji ekhethiwe yeCopaxone ngaphakathi kwedivayisi. I- okuzenzakalelayoject 2 ifihla inaliti yesirinji futhi ikuvumela ukuthi ujove umuthi ngokucindezela inkinobho, esikhundleni sokucindezela phansi isipontsho.

Imiyalo yokujova imithamo yeCopaxone inikezwa ephepheni lephepha elivela ekhemisi lakho neCopaxone.

Ngaphezu kwalokho, umenzi wezidakamizwa uphinde anikeze umhlahlandlela wokujova kanye nevidiyo yokufundisa ngesinyathelo ngesinyathelo. Lezi zinsizakusebenza zichaza kabanzi mayelana nokuthi isetshenziswa kanjani imijovo yeCopaxone kanye ne okuzenzakalelayoject 2 idivayisi. Futhi bachaza izilungiselelo zokujula komjovo okufanele ukhethe lapho usebenzisa i- okuzenzakalelayoject 2 idivayisi.

Amasayithi wokujova weCopaxone

Ungajova iCopaxone ngaphansi kwesikhumba salezi zindawo ezilandelayo zomzimba wakho:

  • isisu sakho (isisu), uma ugwema ukujova endaweni engaphakathi kwamasentimitha ama-2 enkinobho yesisu sakho
  • ingaphambili lamathanga akho, uma ujova endaweni engamayintshi ama-2 ngaphezu kwedolo lakho namasentimitha ama-2 ngaphansi kwesibumbu sakho
  • ngemuva kwezinqulu zakho ngezansi kokhalo lwakho
  • ngemuva kwezingalo zakho ezingaphezulu

Khuluma nodokotela wakho mayelana nokuthi yiziphi kulezi zindawo zokujova ezingcono kakhulu kuwe. Khumbula ukuthi isikhathi ngasinye lapho ufaka umthamo weCopaxone, kufanele ujikeleze amasayithi wokujova owasebenzisayo. Ungasebenzisi indawo efanayo yokujova ngaphezu kwesisodwa ngesonto.

Kuyasiza ukugcina irekhodi lezindawo zokujova ozisebenzisayo kumthamo ngamunye weCopaxone. Eqinisweni, kukhona uhlelo lokusebenza lwe-Copaxone tracker olutholakala kuwebhusayithi yomkhiqizi elingakusiza ukwenza lokhu.

Amathiphu wokuthatha iCopaxone

Uma usebenzisa iCopaxone, gcina la macebiso alandelayo engqondweni:

  • Thatha iCopaxone esiqandisini cishe imizuzu engama-20 ngaphambi kokuhlela ukujova umthamo wakho. Lokhu kunikeza isikhathi somuthi ukufudumala kufudumale ekamelweni, okwenza umjovo ukhululeke kakhudlwana kuwe.
  • Imijovo yeCopaxone kufanele inikezwe kuphela ngaphansi kwesikhumba sakho. Ungawufaki lo muthi komunye wemithambo noma imisipha yakho.
  • Ungayifaki i-Copaxone ezindaweni zesikhumba sakho ezibomvu, ezivuvukile, ezinamaqhuqhuva, nezibazi, noma ezigoqiwe. Futhi gwema ukufaka imijovo ezindaweni zesikhumba ezinezimpawu zokuzalwa, ama-stretch marks, noma ama-tattoos.
  • Musa ukugcoba noma ukubhucunga indawo yakho yokujova iCopaxone okungenani amahora angama-24 ngemuva kokujova umuthi.

Ukuthatha nini

Lapho uzothatha iCopaxone kuya ngokuthi imaphi amandla omuthi owasebenzisayo. Amashejuli esikali weCopaxone ami kanjena:

  • I-Copaxone 20 mg. Uma usebenzisa la mandla, uzofaka umuthi kanye ngosuku, ngasikhathi sinye usuku ngalunye. Akunandaba ukuthi ukhetha isikhathi sini, inqobo nje uma ungaguquguquki usuku ngalunye.
  • I-Copaxone 40 mg. Uma usebenzisa la mandla, uzofaka umuthi kathathu ngesonto. Isibonelo, ungenza imijovo yakho ngoMsombuluko, ngoLwesithathu nangoLwesihlanu. Vele uqiniseke ukuthi imijovo ithathwa okungenani amahora angama-48.

Ukusiza ukuqinisekisa ukuthi awuphuthelwa umthamo, zama ukusetha isikhumbuzi efonini yakho. Izikhumbuzi zingasethwa futhi kuhlelo lokusebenza lwe-Copaxone tracker.

Isikali seCopaxone

Imininingwane elandelayo ichaza imithamo esetshenziswa kakhulu noma enconywayo. Kodwa-ke, qiniseka ukuthatha isilinganiso udokotela wakho akubekela sona. Udokotela wakho uzonquma isilinganiso esihle kakhulu ukulingana nezidingo zakho.

Amafomu wezidakamizwa namandla

ICopaxone iza njengomthamo owodwa, imijovo ekhethiwe. Itholakala ngamandla amabili: 20 mg no-40 mg.

Isilinganiso se-MS

ICopaxone inezilinganiso ezilandelayo ezinconyiwe ze-multiple sclerosis (MS):

  • U-20 mg uthathwe kanye ngosuku
  • U-40 mg uthathwe kathathu ngesonto

Udokotela wakho angakunika noma iyiphi yalezi shejuli zomthamo, kuya ngokuthi iyiphi elungele isimo sakho esiyingqayizivele.

Kuthiwani uma ngiphuthelwa umthamo?

Okufanele ukwenze uma uphuthelwa umthamo weCopaxone kuya ngesilinganiso somuthi owuthathayo. Ngezansi, sichaza okufanele sikwenze kumthamo ngamunye onconyiwe.

Ungaphinda ushayele ihhovisi likadokotela wakho uma uphuthelwa umthamo weCopaxone futhi awuqiniseki ukuthi yini okufanele uyenze. Udokotela wakho noma abasebenzi babo bezokwelapha bangancoma lapho kufanele uthathe umthamo wakho olandelayo womuthi.

Futhi ukusiza ukuqinisekisa ukuthi awuphuthelwa umthamo, zama ukusetha isikhumbuzi efonini yakho, noma usebenzise uhlelo lokusebenza lwe-Copaxone tracker.

Umthamo olahlekile weCopaxone 20 mg nsuku zonke

Uma ujwayele ukuthatha iCopaxone 20 mg nsuku zonke, thatha umthamo ongabanjwanga ngokushesha nje lapho ukhumbula. Kepha uma iseduze nomthamo wakho olandelayo ohleliwe kunaleyo oyiphuthiwe, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi imithamo emibili ndawonye ukwenza umthamo ongabanjwanga.

Umthamo olahlekile weCopaxone 40 mg kathathu ngesonto

Uma ujwayele ukuthatha iCopaxone 40 mg bese uphuthelwa umthamo, yithathe ngosuku olulandelayo ngesikhathi sakho esijwayelekile. Bese uthatha umthamo wakho olandelayo ngemuva kwezinsuku ezi-2 ngesikhathi sakho esijwayelekile. Zama ukubuyela esimisweni sakho esivamile ngesonto elilandelayo. Kepha khumbula, kufanele kuhlale kukhona okungenani amahora angama-48 phakathi kwamanani akho.

Isibonelo, uma uvame ukuthatha iCopaxone ngoMsombuluko, uLwesithathu nangoLwesihlanu, kepha uphuthelwa umthamo wakho wangoMsombuluko, thatha umthamo owuphuthelwe ngoLwesibili. Ngemuva kwalokho thatha imithamo yakho esele yalelo sonto ngoLwesine nangoMgqibelo. Ngesonto elilandelayo, ungabuyela esimisweni sakho esijwayelekile.

Ngabe kuzodingeka ngisebenzise lesi sidakamizwa isikhathi eside?

I-Copaxone yenzelwe ukuthi isetshenziswe njengokwelashwa kwesikhathi eside. Uma wena nodokotela wakho nibona ukuthi iCopaxone iphephile futhi iyasebenza kuwe, cishe uzoyithatha isikhathi eside.

Ezinye izindlela zeCopaxone

Ezinye izidakamizwa ziyatholakala ezingelapha i-multiple sclerosis (MS), kanye nesifo sodwa sasemtholampilo (CIS). (I-CIS yisimo esidala izimpawu ezifana ne-MS.)

Eminye imishanguzo ehlukile ingakulungela kangcono kunabanye. Uma unentshisekelo yokuthola enye indlela ye-Copaxone, khuluma nodokotela wakho. Bangakutshela ngeminye imithi engakusebenzela kahle.

Izibonelo zezinye izidakamizwa ezingasetshenziswa ukwelapha i-MS noma i-CIS zifaka:

  • i-corticosteroids, esetshenziselwa ukwelapha izimpawu ze-MS noma iziqephu ze-CIS, njenge:
    • i-methylprednisolone (Medrol)
    • i-prednisone (iRayos)
  • Imithi yokwelapha yokuguqula izifo ethathwa ngomlomo, njenge:
    • i-dimethyl fumarate (iTecfidera)
    • i-diroximel fumarate (Ubuningi)
    • i-fingolimod (Gilenya)
    • i-siponimod (Mayzent)
    • teriflunomide (Aubagio)
  • Izindlela zokwelapha eziguqula izifo ezithathwa ngokuzilimaza, njenge:
    • i-glatiramer acetate (Glatopa)
    • i-interferon beta-1a (Avonex, Rebif)
    • i-interferon beta-1b (iBetaseron, i-Extavia)
    • i-peferlated interferon beta-1a (iPlegridy)
  • Imithi yokwelapha yokuguqula izifo enikezwa ngemithambo yegazi (ijojowe emthanjeni wakho), efana nale:
    • i-alemtuzumab (Lemtrada)
    • i-natalizumab (Tysabri)
    • ocrelizumab (Ocrevus)

ICopaxone vs. Glatopa

Ungase uzibuze ukuthi iCopaxone iqhathaniswa kanjani neminye imithi enqunyelwe ukusetshenziswa okufanayo. Lapha sibheka ukuthi iCopaxone neGlatopa ziyefana futhi zehlukene kanjani.

Izithako

ICopaxone neGlatopa zombili ziqukethe umuthi ofanayo osebenzayo: i-glatiramer acetate.

Kodwa-ke, ngenkathi iCopaxone ingumuthi wegama lomkhiqizo, iGlatopa iyindlela ejwayelekile yeCopaxone. Umuthi ojwayelekile ikhophi eliqondile lomuthi osebenzayo emithini enegama lomkhiqizo.

Isebenzisa

ICopaxone neGlatopa zombili zivunyelwe ukwelapha izinhlobo ezithile ze-multiple sclerosis (MS) kubantu abadala.

Ngokuqondile, iCopaxone neGlatopa kungasetshenziswa ukwelapha lezi zimo ezilandelayo:

  • isifo esihlukaniswe ngokwasemtholampilo (i-CIS)
  • i-MS ebuyisa kabusha (RRMS)
  • i-MS yesibili eqhubekayo esebenzayo (SPMS)

ICopaxone neGlatopa zombili zibizwa ngemithi yokuguqula izifo. Zisebenza ngokusiza ukumisa amasosha omzimba wakho ekuhlaseleni izinzwa zakho. Le mithi inganciphisa inani lokuphindaphinda kwe-MS onayo futhi yehlise nesifo sakho ukuthi singabi sibi.

Amandla amafomu nezidakamizwa

Kokubili iCopaxone neGlatopa kuza njengezixazululo ngaphakathi komthamo owodwa, imijovo ekhethiwe. Zonke zinikezwa ngomjovo ongaphansi (umjovo ngaphansi kwesikhumba sakho). Ngokuya ngamandla omuthi udokotela akunqumela wona, uzothatha umuthi ngamunye kanye kanye ngosuku noma kathathu ngesonto.

Umhlinzeki wakho wezokunakekelwa kwezempilo uzokufundisa wena noma umnakekeli wakho ukuthi ungawujova kanjani umuthi.

Ukusebenza ngempumelelo nokuphepha

Ukuphathwa Kwezokudla Nezidakamizwa (i-FDA) kubheka ama-generics ukuthi aphephe futhi asebenza kahle njengomuthi wokuqala. Lokhu kusho ukuthi iGlatopa ibhekwa njengeyimpumelelo ekwelapheni i-MS ne-CIS njenge-Copaxone. Kusho nokuthi iCopaxone neGlatopa kungadala imiphumela emibi efanayo.

Ukuze ufunde ngemiphumela emibi futhi emibi ye-Copaxone, bheka isigaba "Imiphumela emibi yeCopaxone" ngenhla.

Izindleko

ICopaxone isidakamizwa esinegama lomkhiqizo, kuyilapho iGlatopa inguhlobo olujwayelekile lweCopaxone. Imithi enegama lomkhiqizo imvamisa ibiza ngaphezu kwezindleko zemithi ejwayelekile.

Ngokuya ngokulinganiselwa ku-GoodRx.com, iGlatopa ibiza kakhulu ngaphansi kwezindleko zeCopaxone. Kodwa inani langempela ozolikhokhela noma imuphi umuthi lincike ohlelweni lwakho lomshuwalense, indawo okuyo nasekhemisi oyisebenzisayo.

ICopaxone vs. Tecfidera

Ungase uzibuze ukuthi iCopaxone iqhathaniswa kanjani neminye imithi enqunyelwe ukusetshenziswa okufanayo. Lapha sibheka ukuthi iCopaxone neTecfidera zifana kanjani futhi zehlukile.

Izithako

ICopaxone iqukethe i-glatiramer acetate, kuyilapho iTecfidera iqukethe i-dimethyl fumarate.

Isebenzisa

ICopaxone neTecfidera zombili zivunyelwe ukwelapha izinhlobo ezithile ze-multiple sclerosis (MS) kubantu abadala.

Ngokuqondile, iCopaxone neTecfidera zingasetshenziswa ukwelapha lezi zimo ezilandelayo:

  • isifo esihlukaniswe ngokwasemtholampilo (i-CIS)
  • i-MS ebuyisa kabusha (RRMS)
  • i-MS yesibili eqhubekayo esebenzayo (SPMS)

ICopaxone neTecfidera zombili zibizwa ngemithi yokuguqula izifo. Zisebenza ngokusiza ukumisa amasosha omzimba wakho ekuhlaseleni izinzwa zakho. Le mithi inganciphisa inani lokuphindaphinda kwe-MS onayo futhi yehlise nesifo sakho ukuthi singabi sibi.

Amafomu wezidakamizwa nokuphathwa

ICopaxone iza njengesisombululo ngaphakathi komthamo owodwa, imijovo ekhethiwe. Kuthathwe ngomjovo ongaphansi (umjovo ngaphansi kwesikhumba sakho). Ngokuya ngamandla omuthi okushiwo udokotela wakho, ingathathwa kanye ngosuku noma kathathu ngesonto. Umhlinzeki wakho wezokunakekelwa kwezempilo uzokufundisa noma anakekele umhlinzeki wakho ukuthi ungasisebenzisa kanjani lesi sidakamizwa.

I-Tecfidera, ngakolunye uhlangothi, iza njengamaphilisi athathwa ngomlomo. Kuthathwa kabili ngosuku.

Imiphumela emibi kanye nezingozi

ICopaxone neTecfidera zombili ziqukethe umuthi olungisa izifo. Kodwa-ke, le mithi isebenza ngezindlela ezahlukene emzimbeni wakho. I-Copaxone ne-Tecfidera zingadala imiphumela emibi efanayo nengafani. Ngezansi kunezibonelo zale miphumela emibi.

Imiphumela emibi emincane

Lezi zinhlu zinemiphumela emibi ebalelwa eshumini evame ukwenzeka ngeCopaxone, neTecfidera, noma ngeCopaxone neTecfidera (uma ithathwa ngawodwana).

  • Kungenzeka ngeCopaxone:
    • ukuphendula kwesiza somjovo, okungadala ububomvu, ubuhlungu, ukulunywa, izigaxa, noma ukuvuvukala endaweni yomjovo wakho
    • ukuphelelwa umoya
    • ukukhathazeka
    • ubuthakathaka
    • izifo, njengomkhuhlane ovamile nomkhuhlane
    • ubuhlungu emhlane wakho noma kwezinye izitho zomzimba wakho
    • ukushaya kwenhliziyo (uzizwe sengathi inhliziyo yakho iyagijima, ishaya, noma ishaya ngamandla)
    • ajuluke ngaphezu kokujwayelekile
    • ukushintsha kwesisindo, kufaka phakathi ukuzuza kwesisindo noma ukwehla kwesisindo
  • Kungenzeka ngeTecfidera:
    • ubuhlungu besisu (esiswini)
    • isifo sohudo
    • ukugaya ukudla
  • Kungenzeka ngeCopaxone neTecfidera:
    • ukuqhuma
    • isicanucanu nokuhlanza
    • ukuqubuka kwesikhumba

Imiphumela emibi kakhulu

Lezi zinhlu ziqukethe izibonelo zemiphumela emibi engaba khona neCopaxone, neTecfidera, noma ngazo zombili izidakamizwa (uma zithathwa ngazodwana).

  • Kungenzeka ngeCopaxone:
    • post reaction reaction (ukusabela okwenzeka ngaphakathi komzimba wakho ngemuva nje kokuthola umjovo wezidakamizwa)
    • ubuhlungu besifuba
    • ukulimala kwesikhumba endaweni yemijovo yakho
  • Kungenzeka ngeTecfidera:
    • i-lymphopenia (ukwehla kwezinga lamaseli amhlophe egazi abizwa ngama-lymphocyte)
    • i-leukoencephalopathy eqhubekayo ye-multifocal (PML), okuyisifo esisongela impilo ebuchosheni bakho
    • ezinye izifo ezinzima, njenge-shingles (ukutheleleka okubangelwa i-herpes zoster virus)
    • ukulimala kwesibindi
  • Kungenzeka ngeCopaxone neTecfidera:
    • ukusabela okweqile komzimba

Ukusebenza ngempumelelo

ICopaxone neTecfidera zombili zivunyelwe ukwelapha izinhlobo ezithile ze-MS kanye ne-CIS. Le mithi ayikaze iqhathaniswe ngqo ezifundweni zokwelashwa. Kepha izifundo ezihlukile zithole ukuthi iCopaxone neTecfidera ziyasebenza ekwelapheni lezi zimo.

Ukubuyekezwa okukodwa kwezifundo kwathola ukuthi iTecfidera yayisebenza kangcono kuneCopaxone ekwehliseni inani lokuphindelela kwe-MS futhi yehlise ukwanda kokukhubazeka okubangelwa yi-MS.

Ngaphezu kwalokho, olunye ucwaningo luthole iTecfidera isebenza kangcono kuneCopaxone ekwehliseni inani lokuphindelela kwe-MS. Kodwa-ke, lolu cwaningo luthole ukuthi le mithi ibisebenza ngendlela efanayo ekwehliseni ukwanda kokukhubazeka okubangelwa yi-MS.

Uma unentshisekelo yokuphuza eyodwa yalezi zidakamizwa nge-MS, khuluma nodokotela wakho. Bangancoma ukuthi imuphi umuthi ongakulungela kakhulu.

Izindleko

ICopaxone neTecfidera zombili izidakamizwa zomuthi. ICopaxone iyatholakala futhi ngendlela ejwayelekile. Okwamanje awekho amafomu ejwayelekile we-Tecfidera atholakalayo. Imithi enegama lomkhiqizo ivame ukubiza ngaphezu kwama-generic.

Ngokuya ngokulinganiselwa ku-WellRx.com, iTecfidera ibiza kakhulu kunezindleko zeCopaxone. Kodwa inani langempela ozolikhokhela noma imuphi umuthi lincike ohlelweni lwakho lomshuwalense, indawo okuyo nasekhemisi oyisebenzisayo.

I-Copaxone ye-MS

Ukuphathwa Kwezokudla Nezidakamizwa (i-FDA) kuvumela imishanguzo kadokotela efana neCopaxone ukwelapha izimo ezithile. ICopaxone nayo ingasetshenziswa ngaphandle kwelebula ngezinye izimo. Ukusetshenziswa okungekho kwelebula kulapho umuthi ovunyelwe ukwelapha umbandela owodwa usetshenziselwa ukwelapha isimo esihlukile.

ICopaxone ivunyelwe yi-FDA ukwelapha amafomu abuyayo e-multiple sclerosis (MS) kubantu abadala. Isidakamizwa siphinde samukelwa ukwelapha i-syndrome ehlukanisiwe emitholampilo kubantu abadala. (I-CIS yisimo esidala izimpawu ezifana ne-MS.)

Ngokuqondile, iCopaxone ingasetshenziselwa ukwelapha lezi zimo ezilandelayo:

  • I-CIS. Nge-CIS, unesiqephu sezimpawu ezifana ne-MS ezihlala okungenani amahora angama-24. I-CIS kungenzeka noma ingakhuli ibe yi-MS.
  • Ukubuyisela kabusha i-MS (RRMS). Ngaleli fomu le-MS, unezikhathi lapho izimpawu zakho ze-MS ziphinda zivele (zivuleka) zilandelwa yizikhathi lapho izimpawu zakho ze-MS zikhululiwe (zithuthukisiwe noma sezihambile).
  • Kuyasebenza i-MS yesibili eqhubekayo (SPMS). Ngaleli fomu le-MS, isimo sakho siya ngokuya siba sibi, kepha usenezikhathi zokubuyela emuva. Ngesikhathi sokubuyela emuva, izimpawu zakho ziba zimbi kakhulu isikhashana.

Nge-MS, amasosha akho omzimba ahlasela ngephutha izinzwa zakho. Izinzwa ezilimele bese zinenkinga yokuxhumana nobuchopho bakho. Lesi simo singadala izimpawu ezahlukahlukene, kuya ngokuthi yiziphi izinzwa ezilimele.

Ngamafomu abuyela emuva we-MS, uneziqephu zomonakalo wezinzwa obangela izimpawu ezintsha ze-MS. Noma ungaba nezikhathi lapho izimpawu zakho ze-MS zibuya noma ziba zimbi kakhulu ngemuva kokuba sezithuthukile.

ICopaxone iyindlela yokwelapha yokuguqula izifo. Kuyasebenza ukwelapha i-MS ne-CIS ngokusiza ukumisa amasosha omzimba wakho ekuhlaseleni izinzwa zakho. Ngokwenza lokhu, lesi sidakamizwa singanciphisa inani lokuphindaphinda kwe-MS onaso futhi sinciphise ukwanda kwesifo sakho.

Ukusebenza kwe-MS

Ezifundweni eziningana zemitholampilo, iCopaxone yayiphumelela ekwelapheni amafomu okubuyisela emuva we-MS. Ngokuqondile, iCopaxone inciphise inani le-MS elibuyela emuva kubantu. Futhi lesi sidakamizwa sinciphise inani lezilonda zobuchopho (izindawo zokulimala kwemizwa) abantu ababenalesi sifo. I-Copaxone ibuye yehlise i-MS ekubeni yande kubantu abasebenzisa lesi sidakamizwa.

Isibonelo, izifundo ezimbili zibheke umphumela wokusebenzisa i-Copaxone 20 mg nsuku zonke kubantu abane-MS. Iminyaka engaphezu kwengu-2 yokwelashwa:

  • Abantu abathathe iCopaxone banesilinganiso esiphindwe kabili se-0.6 kuye ku-1.19 MS. Ngokuqhathanisa, abantu abathathe i-placebo (asikho isidakamizwa esisebenzayo) babenesilinganiso esiphindwe kabili se-1.68 kuye ku-2.4 MS.
  • Ama-34% kuya kuma-56% abantu abathathe iCopaxone abazange baphinde babhekane ne-MS. Ngokuqhathanisa, ama-27% kuya ku-28% wabantu abathathe i-placebo abanayo i-MS ebuyela emuva.

Ngaphezu kwalokho, ucwaningo olulodwa lubheke umphumela wokusebenzisa iCopaxone 20 mg nsuku zonke ekukhuleni kwezilonda ezithile zobuchopho. Lezi zilonda, ezikhombise izindawo zokuvuvukala ebuchosheni, zikhonjwe ngezikena ze-MRI. Ukwelashwa izinyanga ezingaphezu kwezingu-9:

  • uhhafu wabantu abathathe iCopaxone baba nezilonda ezintsha okungenani eziyi-11
  • uhhafu wabantu abathathe i-placebo baba nezilonda ezintsha okungenani eziyi-17

Olunye ucwaningo lubheke umphumela wokusebenzisa iCopaxone 40 mg kathathu ngesonto kubantu abane-MS. Ngonyaka owodwa wokwelashwa, uma kuqhathaniswa nabantu abasebenzisa i-placebo, abantu abasebenzisa iCopaxone babene:

  • Ingozi ephansi engama-34% yokubuyela emuva kwe-MS
  • Ingozi ephansi engama-45% yezilonda zobuchopho ekhombise izindawo ezivuthayo ebuchosheni babo
  • Ingozi ephansi engama-35% yezilonda zobuchopho ezintsha noma ezikhulayo ezikhombise izindawo ezilimele ebuchosheni bazo

Ukusebenza kwe-CIS

Ucwaningo lomtholampilo lubheke ukwelashwa kweCopaxone kubantu abane-CIS. Kulolu cwaningo, iCopaxone inciphise ubungozi babantu bokuthola isiqephu sesibili sezimpawu ezifana ne-MS.

Ngaphezulu kweminyaka emithathu yokwelashwa, abantu abathathe i-Copaxone 20 mg nsuku zonke babenamathuba amancane okuba ne-45% yokuthola isiqephu sesibili sezimpawu ezifana ne-MS kunabantu ababethatha i-placebo.

ICopaxone nezingane

I-Copaxone ayivunyelwe ukusetshenziswa ezinganeni ezineminyaka engu-17 noma ngaphansi. Kodwa-ke, kwesinye isikhathi umuthi usetshenziswa ngaphandle kwelebuli ukwelapha i-MS ezinganeni. (Ngokusetshenziswa kwelebula engekho, umuthi ovunyelwe izimo ezithile usetshenziselwa ezinye izimo.)

Olunye ucwaningo lukhombisile ukuthi i-glatiramer (umuthi osebenzayo eCopaxone) unganciphisa inani le-MS elibuyela ezinganeni. Ucwaningo luphinde lwabonisa ukuthi lesi sidakamizwa sinciphise ukwanda kokukhubazeka okubangelwa yi-MS. Ngaphezu kwalokho, i-International Pediatric Multiple Sclerosis Study Group incoma ukusebenzisa iCopaxone njengenye yezindlela zokuqala ukwelashwa ezinganeni ezine-MS.

Uma unemibuzo mayelana nokusebenzisa i-Copaxone ukwelapha i-MS enganeni, khuluma nodokotela wakho.

Ukuphelelwa yisikhathi kwe-Copaxone, ukugcina nokulahla

Uma uthola i-Copaxone ekhemisi lakho, usuku lokuphelelwa yisikhathi komuthi luzophrintwa ebhokisini lamasirinji, kanye nakumajojo ngokwawo. Usuku lokuphelelwa yisikhathi lusiza ekuqinisekiseni ukuthi umuthi uyasebenza kahle ngesikhathi esithile.

Isimo samanje se-Food and Drug Administration (i-FDA) ukugwema ukusebenzisa imishanguzo ephelelwe yisikhathi. Uma usebenzise umuthi ongasetshenziswanga osudlulile esikhathini sokuphelelwa yisikhathi, khuluma nosokhemisi wakho mayelana nokuthi usengakwazi yini ukuwusebenzisa.

Isitoreji

Ukuthi umuthi uhlala ulungile isikhathi eside kangakanani kungancika ezintweni eziningi, kufaka phakathi ukuthi uwugcina kanjani futhi kuphi umuthi.

Imijovo ekhethiwe yeCopaxone kufanele igcinwe esiqandisini ezingeni lokushisa elingu-36 ° F kuye ku-46 ° F (2 ° C kuye ku-8 ° C). Ungafrizi imijovo yeCopaxone. Uma isirinji iba yiqhwa, ungayisebenzisi. Esikhundleni salokho, lahla isirinji esitsheni esibukhali.

Uma ungakwazi ukufaka iCopaxone esiqandisini, njengalapho usohambweni, ungagcina umuthi ekamelweni lokushisa (59 ° F kuye ku-86 ° F / 15 ° C kuye ku-30 ​​° C). Kodwa-ke, ungagcina kuphela iCopaxone ekamelweni lokushisa kuze kube yinyanga engu-1. Futhi ngenkathi umuthi ugcinwa ngaphandle kwesiqandisi, qiniseka ukuthi izinga lokushisa alikhuphukeli ngaphezu kuka-86 ° F (30 ° C).

Kungakhathaliseki ukuthi ugcina iCopaxone esiqandisini noma ekamelweni lokushisa, kufanele ugcine imijovo emaphaketheni abo ngamanye amabhamuza, ngaphakathi kwebhokisi labo lokuqala. Ukwenza lokhu kuzovikela umuthi ekukhanyeni.

Ukulahlwa

Ngemuva nje kokusebenzisa isirinji, inaliti, noma i-autoinjector, yilahle esitsheni sokulahla esivunyelwe i-FDA. Lokhu kusiza ukuvimbela abanye, kufaka phakathi izingane nezilwane ezifuywayo, ekuthatheni lesi sidakamizwa ngengozi noma ukuzilimaza ngenaliti. Ungathenga isitsha esibukhali online, noma ubuze udokotela wakho, usokhemisi, noma inkampani yomshuwalense wezempilo ukuthi ungayithola kuphi.

Lo mbhalo unikeza ngamathiphu amaningi awusizo ngokulahlwa kwemithi. Ungabuza futhi usokhemisi wakho imininingwane yokuthi ungayilahla kanjani imithi yakho.

Imibuzo ejwayelekile ngeCopaxone

Nazi izimpendulo zemibuzo ebuzwa njalo ngeCopaxone.

Ngizoba nezimpawu zokuhoxa noma imiphumela emibi ngemuva kokumisa iCopaxone?

Cha, akunakwenzeka lokho. Izimpawu zokuhoxa ziyimiphumela engemihle engenzeka lapho uyeka ukuthatha umuthi umzimba wakho othembele kuwo. (Ngokuncika, umzimba wakho udinga umuthi ukuze uzizwe ujwayelekile.)

Ukumisa iCopaxone akwaziwa ukuthi kungadala noma yiziphi izimpawu zokuhoxa. Ngenxa yalokhu, awudingi ukuyeka ukuthatha umuthi kancane kancane, njengoba wenza ngemithi ethile engadala izimpawu zokuhoxa.

Kodwa-ke, khumbula ukuthi ukumisa iCopaxone kungadala ukuthi i-multiple sclerosis (MS) yakho ibuyele emuva noma ibe yimbi kakhulu.

Uma unemibuzo mayelana nokumisa iCopaxone, khuluma nodokotela wakho. Bangakhuluma nawe ngobungozi nezinzuzo zokumisa lo muthi.

Ingabe ukusebenzisa iCopaxone kuyayandisa ingozi yokuba nomdlavuza?

Cha. Njengamanje kucatshangwa ukuthi ayikho ingozi eyengeziwe yomdlavuza ngokusetshenziswa kweCopaxone. Ngenkathi kunemibiko ethile yomdlavuza kubantu abathatha lesi sidakamizwa ngemuva kokuthi sikhishwe emakethe, le mibiko yayingavamile. Futhi ingozi eyengeziwe yomdlavuza ayizange ixhunyaniswe ngqo nokusetshenziswa kweCopaxone.

Kodwa-ke, ezinye izidakamizwa ezisetshenziselwa ukwelapha i-multiple sclerosis (MS), njengalezo ezibangela ukucindezelwa komzimba, zingandisa ingozi yomdlavuza. Izibonelo zalezi ezinye izidakamizwa zifaka i-alemtuzumab (Lemtrada) ne-mitoxantrone.

Imvamisa amasosha akho omzimba abulala amagciwane, kanye namaseli emzimbeni wakho angajwayelekile noma angasebenzi kahle. Lesi senzo sisiza ukukuvikela ekuthuthukiseni umdlavuza kanye nokutheleleka. Kodwa ngokucindezela kokuzivikela komzimba, amasosha akho omzimba ayacindezelwa (abe buthakathaka) futhi awasebenzi ngendlela efanele. Uma amasosha akho omzimba ecindezelwe, unengozi enkulu yokuba nomdlavuza kanye nezifo ezithile.

I-Copaxone yenza ezinye izingxenye zesistimu yakho yokuzivikela zingasebenzi kakhulu kunokujwayelekile. Kodwa-ke, iCopaxone ibizwa nge-immunomodulator, kune-immunosuppressant. Lokho kungenxa yokuthi iCopaxone iyashintsha indlela amasosha akho omzimba asebenza ngayo, kunokuba icindezele amasosha akho omzimba.

Uma unemibuzo mayelana nezingozi zokwelashwa kweCopaxone, khuluma nodokotela wakho.

Ingabe iCopaxone iyi-biologic?

Cha, iCopaxone akuyona i-biologic. I-biologics yizidakamizwa ezenziwe ngamaseli aphilayo. ICopaxone yenziwa ngamakhemikhali.

Ezinye izindlela zokwelapha eziguqula izifo ezisetshenziselwa ukwelapha i-multiple sclerosis (MS) zingu-biologics, kodwa iCopaxone akuyona enye yazo. Izibonelo ze-biologics ezisetshenziselwa ukwelapha i-MS zifaka i-alemtuzumab (Lemtrada), natalizumab (Tysabri), ne-ocrelizumab (Ocrevus).

Ngemininingwane yokuthi iCopaxone isebenza kanjani ukwelapha i-MS, bheka isigaba esithi “Isebenza kanjani iCopaxone” ngezansi.

Ungathatha isikhathi esingakanani iCopaxone?

I-Copaxone yenzelwe ukuthi isetshenziswe njengokwelashwa kwesikhathi eside. Ngokuvamile, ungaqhubeka nokuyithatha inqobo nje uma iqhubeka iphephile futhi isebenza kahle kuwe.

Kepha uma uba nemiphumela emibi ekhathazayo noma enamandla, noma umuthi ungasilawuli isimo sakho ngokwanele, kungadingeka ukuthi ushintshele ekwelashweni okuhlukile. Uma kunjalo, udokotela wakho uzokuncomela enye indlela yokwelashwa.

Uma unemibuzo mayelana nokuthi kufanele uthathe i-Copaxone isikhathi esingakanani, khuluma nodokotela wakho.

Nginganikela ngegazi uma ngithatha iCopaxone?

Yebo. Ngokwe-American Red Cross, ukuthatha iCopaxone akufanele kukuvikele ekunikeni igazi. Futhi kuhle futhi ukunikela ngegazi uma une-multiple sclerosis (MS), inqobo nje uma isimo sakho siphethwe kahle futhi njengamanje uphile saka.

Uma unemibuzo mayelana nokuthi kuphephile yini ukunikela ngegazi, khuluma nodokotela wakho. Noma ungaxhumana ne-American Red Cross ngokuvakashela iwebhusayithi yabo.

I-Copaxone nokukhulelwa

ICopaxone ayikaze ifundwe kwabesifazane abakhulelwe. Ngakho-ke akwaziwa ngokuqinisekile ukuthi umuthi uphephile yini ukuwuthatha ngesikhathi sokukhulelwa.

Abanye besifazane bathathe iCopaxone ngesikhathi sokukhulelwa. Kodwa alukho ulwazi olwanele olutholakalayo ukusho ukuthi ngabe umuthi uyabandisa yini ubungozi bokukhubazeka kokuzalwa noma ukukhulelwa kwesisu.

Izifundo zezilwane zenziwe kwabesifazane abakhulelwe abanikezwa iCopaxone. Futhi lezi zifundo azibonisanga okubi emibungwini lapho kusetshenziswa umuthi. Kepha khumbula ukuthi izifundo ezenziwe ezilwaneni azihlali zibikezela ukuthi kuzokwenzekani kubantu.

Uma ukhulelwe noma ungakhulelwa, khuluma nodokotela wakho mayelana nokuthi iCopaxone ikulungele yini. Futhi uma usuvele uthatha iCopaxone futhi ukhulelwa, qiniseka ukuthi ushayela udokotela wakho ngokushesha.

I-Copaxone nokulawulwa kokuzalwa

Akwaziwa ukuthi iCopaxone iphephile yini ukuyithatha ngesikhathi sokukhulelwa. Uma uhlanganyela ocansini futhi wena noma umlingani wakho ningakhulelwa, khuluma nodokotela wakho ngezidingo zakho zokulawula ukubeletha ngenkathi usebenzisa iCopaxone.

I-Copaxone nokuncelisa

Akwaziwa ukuthi iCopaxone idlulela ebisini lwebele noma uma ingathinta ingane encelisiwe.

Uma uncelisa noma uhlela ukuncelisa, khuluma nodokotela wakho mayelana nokuthi iCopaxone ikufanele yini.

ICopaxone notshwala

Utshwala abaziwa ukusebenzisana neCopaxone. Kodwa-ke, uma unemiphumela ethile emibi evela ku-Copaxone, njengokugungxula noma isicanucanu, ukuphuza utshwala kungayilimaza imiphumela yakho emibi.

Ngemuva kokuthi iCopaxone ikhishelwe emakethe, kunemibiko yabantu abasebenzisa lesi sidakamizwa esinokubekezelela utshwala. (Ngokungabekezelelani kotshwala, ungahle ube nokusabela okuthile ngemuva nje kokuphuza utshwala. Lokhu kusabela kungabandakanya ukufutha ebusweni bakho noma ikhala eligcwele.)

Noma kunjalo, le mibiko yayingavamile. Futhi ukungabekezelelani notshwala akuzange kuxhunyaniswe ngqo nokusetshenziswa kweCopaxone.

Izingozi zokusetshenziswa kotshwala kubantu abane-multiple sclerosis (MS) azaziwa ngokuqinisekile. Uma uphuza utshwala, khuluma nodokotela wakho ngokuthi kungakanani okuphephile ongakudla.

Ukusebenzisana kweCopaxone

Akukho ukuxhumana okwaziwayo phakathi kweCopaxone neminye imithi, amakhambi, izithasiselo, noma ukudla.

Kodwa-ke, ngaphambi kokuthatha iCopaxone, khuluma nodokotela wakho kanye nosokhemisi. Batshele ngayo yonke imishanguzo oyinikezwa ngudokotela, i-counter-counter, nezinye izidakamizwa oziphuzayo. Batshele futhi nganoma yimaphi amavithamini, amakhambi, nezithako ozisebenzisayo. Ukwabelana ngalolu lwazi kungakusiza ugweme ukuhlangana okungenzeka.

Uma unemibuzo mayelana nokuhlangana kwezidakamizwa okungakuthinta, buza udokotela wakho noma usokhemisi.

Isebenza kanjani iCopaxone

I-Copaxone ivunyelwe ukwelapha amafomu abuyela emuva e-multiple sclerosis (MS) kanye ne-syndrome eyedwa emtholampilo (CIS). (I-CIS yisimo esidala izimpawu ezifana ne-MS.)

Kwenzekani ku-MS?

I-MS yisimo sesikhathi eside esiba sibi ngokuhamba kwesikhathi. Ithinta isimiso sakho sezinzwa esiyinhloko (CNS), esakhiwa ubuchopho bakho nentambo yomgogodla. I-CNS yakho nayo yakhiwe yimithambo ethumela imiyalezo phakathi kobuchopho bakho nawo wonke umzimba wakho.

Ngayinye yalezi zintambo zezinzwa izungezwe ungqimba oluvikelayo lwezicubu ezibizwa ngokuthi i-myelin sheath. I-myelin sheath ifana nokwembesa kwepulasitiki okuzungeze izintambo ngaphakathi kwekhebula likagesi. Uma umgogodla ulimele, izinzwa zakho azikwazi ukuhambisa imiyalezo futhi.

Nge-MS, amasosha akho omzimba aqala ngephutha ukuhlasela ama-myelin sheaths azungeze izinzwa zakho. Lokhu kubangela ukuvuvukala okulimaza ama-myelin sheaths. Umonakalo wenza kube nzima ngezinzwa zakho ukuthumela nokwamukela imiyalezo. Ngokuya ngokuthi imiphi imizwa elimele, izimpawu zakho ze-MS zingahluka kancane.

Ngemuva kokuthi amasosha akho omzimba ahlasele i-myelin sheath yakho, izicubu ezibomvu zingakhula zizungeze izindawo ezilimele. Izicubu ezibomvu futhi zenza kube nzima ngezinzwa zakho ukuthumela nokwamukela imiyalezo. Izindawo zomonakalo nezibazi emithanjeni yakho zibizwa ngokuthi izilonda. Lezi zindawo zingabonakala kwizikena ze-MRI, okuyizilingo zokucabanga ezisetshenziselwa ukuqapha i-MS.

Kuyini ukubuyela emuva kwe-MS?

Ngamafomu abuyela emuva we-MS, uzoba nezikhathi lapho izimpawu zakho ziba ngcono noma zihambe ngokuphelele. (Lezi zikhathi zibizwa ngokuthi ukuthethelelwa.) Kodwa futhi uzoba nezikhathi zezimpawu ezintsha ze-MS, noma izikhathi lapho izimpawu zakho ze-MS zibuya noma ziba zimbi kakhulu ngemuva kokuba sezithuthukile. (Lezi zikhathi zibizwa ngokuthi ukubuyela emuva.)

Ukukhululwa kwenzeka lapho amangqamuzana akho ezinzwa ezilungisa wona ekulimaleni okubangelwa yi-MS. Ukukhululwa kungenzeka futhi lapho umzimba wakho wenza izindlela ezintsha zezinzwa ezidlula izinzwa ezonakaliswe yi-MS. Izikhathi zokuxolelwa zingahlala ezinyangeni ezimbalwa kuye eminyakeni embalwa.

Isiqephu ngasinye sokulimala kwemizwa nezimpawu zako ezingaba khona singahlala izinsuku ezimbalwa noma izinyanga ezimbalwa. Lokhu kubizwa ngokuthi yi-MS attack noma i-MS ibuyela emuva. Ngokuhamba kwesikhathi, izimpawu zokubuyela emuva zingase zibe zimbi noma zivame kakhulu. Lokhu kuba kubi kuholela ebunzimeni emisebenzini yansuku zonke njengokuhamba noma ukukhuluma.

Yini i-CIS?

Nge-CIS, unesiqephu esisodwa sezimpawu ezifana ne-MS ezihlala okungenani amahora angama-24. I-CIS ingathuthukela ku-MS noma ingaqhubeki, kepha kungaba uphawu lwe-MS engenzeka. Ngenxa yalokhu, kuvame ukuqoqwa nezinye izimo, njengokuphindaphinda amafomu e-MS.

Wenzani uCopaxone?

I-Copaxone iyindlela yokwelapha yokuguqula izifo yamafomu abuyayo e-MS, kanye ne-CIS. Kubambezela ukulimala kwezinzwa okubangelwa yi-MS futhi kubambezela ukwanda kwesifo.

I-Copaxone iqukethe i-acetate yesidakamizwa esisebenzayo i-glatiramer. Yiprotheni elenziwe elebhu. Kodwa-ke, ifana kakhulu nelinye lamaprotheni atholakala ngokwemvelo kuzicubu zomzimba wakho ze-myelin.

ICopaxone ibizwa nge-immunomodulator. Isebenza ngokushintsha ukusebenza kwamaseli athile kumasosha akho omzimba. Yize kungaqondakali ngokuphelele ukuthi umuthi usebenza kanjani, kucatshangwa ukuthi usebenze amaseli athile amhlophe egazi, abizwa ngokuthi ama-suppressor T cells. Lawa maseli asebenza ngezindlela eziningana zokumisa amasosha akho omzimba ekuhlaseleni izicubu zakho ze-myelin sheath.

Ngokuhlaselwa okumbalwa emgodleni wakho we-myelin, kufanele ube nokuphindelela okumbalwa kwe-MS. Lokhu kunganciphisa ukuwohloka kwesimo sakho nokukhubazeka okwandayo.

Kuthatha isikhathi esingakanani ukusebenza?

ICopaxone izoqala ukusebenza kungekudala ngemuva kokujova kwakho kokuqala, kodwa akunakwenzeka ukuthi uqaphele ukuthi iyasebenza. Lokhu kungenxa yokuthi umuthi usiza ukuvikela isimo sakho ukuthi singabi sibi kakhulu, kunokuba welaphe izimpawu zakho zamanje.

Kodwa ngesikhathi sokwelashwa, udokotela wakho angabheka ukubona ukuthi iCopaxone iyakusebenzela yini. Ukwenza lokhu, banga-oda izivivinyo ezithile ze-imaging, ezinjenge-MRI scan.

Izindleko zeCopaxone

Njengayo yonke imithi, izindleko zeCopaxone zingahluka.

Intengo yangempela ozoyikhokha incike ohlelweni lwakho lomshuwalense, indawo okuyo nasekhemisi oyisebenzisayo.

Uhlelo lwakho lomshuwalense lungadinga ukuthi uthole ukugunyazwa kwangaphambili ngaphambi kokuvumela ukumbozwa kweCopaxone. Lokhu kusho ukuthi udokotela wakho nenkampani yomshuwalense bazodinga ukuxhumana ngomuthi wakho ngaphambi kokuba inkampani yomshuwalense izokwemboza umuthi. Inkampani yomshwalense izosibuyekeza isicelo bese ikwazisa wena nodokotela wakho ukuthi uhlelo lwakho luzohlanganisa iCopaxone.

Uma ungaqiniseki ukuthi uzodinga ukuthola ukugunyazwa kwangaphambili kweCopaxone, xhumana nenkampani yakho yomshuwalense.

Usizo lwezezimali nolomshuwalense

Uma udinga ukwesekwa kwezezimali ukukhokhela i-Copaxone, noma uma udinga usizo lokuqonda umshuwalense wakho, usizo luyatholakala.

UTeva Neuroscience, Inc., ongumkhiqizi weCopaxone, unikela ngohlelo olubizwa ngeShared Solutions. Lolu hlelo luhlinzeka ngosizo lwezezimali, kufaka phakathi ikhadi le-copay elingasiza ekwehliseni izindleko zeCopaxone.

Ukuthola eminye imininingwane nokuthola ukuthi ukulungele yini ukwesekwa, shayela ku-800-887-8100 noma uvakashele iwebhusayithi yohlelo.

Uhlobo olujwayelekile

ICopaxone itholakala ngendlela ejwayelekile ebizwa nge-glatiramer acetate. Umuthi ojwayelekile ikhophi eliqondile lomuthi osebenzayo emithini enegama lomkhiqizo. Okujwayelekile kuthathwa njengokuphephile nokusebenza ngempumelelo njengomuthi wokuqala. Futhi ama-generic athambekele ekubizeni ngaphansi kwezidakamizwa ezinegama lomkhiqizo.

Ukuthola ukuthi izindleko ze-generic glatiramer acetate ziqhathaniswa kanjani nezindleko zeCopaxone, vakashela iGoodRx.com. Futhi, izindleko ozithola ku-GoodRx.com yilokho ongakukhokha ngaphandle komshwalense. Intengo yangempela ozoyikhokha incike ohlelweni lwakho lomshuwalense, indawo okuyo nasekhemisi oyisebenzisayo.

Uma udokotela wakho enqume iCopaxone futhi unentshisekelo yokusebenzisa i-generic glatiramer acetate esikhundleni salokho, khuluma nodokotela wakho. Bangaba nokuthanda kwenguqulo eyodwa noma enye. Kuzodingeka futhi uhlole uhlelo lwakho lomshuwalense, ngoba lungahlanganisa eyodwa noma enye kuphela.

Ukuqapha kweCopaxone

Ngaphambi kokuthatha iCopaxone, khuluma nodokotela wakho ngomlando wakho wezempilo. ICopaxone kungenzeka ingakulungeli uma unezimo ezithile zezokwelapha noma ezinye izinto ezithinta impilo yakho. Lokhu kufaka phakathi:

  • Ukungezwani komzimba neCopaxone. Ungayithathi iCopaxone uma ngabe uke waba neguliswa yiCopaxone, i-glatiramer acetate (umuthi osebenzayo eCopaxone), noma i-mannitol (isithako esingasebenzi eCopaxone). Uma ungaqiniseki ngemithi yokwaliwa komzimba yakho, khuluma nodokotela wakho.
  • Ukukhulelwa. Akwaziwa ukuthi iCopaxone iphephile yini ukuyisebenzisa ngesikhathi sokukhulelwa. Ngeminye imininingwane, sicela ubheke isigaba “Copaxone nokukhulelwa” ngenhla.
  • Ukuncelisa ibele. Akwaziwa ukuthi iCopaxone idlulela ebisini lwebele. Ngeminye imininingwane, sicela ubheke isigaba se- “Copaxone nokuncelisa ibele” ngenhla.

Qaphela: Ukuthola eminye imininingwane ngemiphumela emibi engaba khona yeCopaxone, bheka isigaba se- "Copaxone side effects" ngenhla.

Ukudlula ngokweqile kweCopaxone

Ungasebenzisi i-Copaxone eningi kunokuba udokotela wakho ancoma. Kweminye imishanguzo, ukwenza kanjalo kungaholela emiphumeleni emibi engafuneki noma ekweqiseni ngokweqile.

Okufanele ukwenze uma kwenzeka uthathe iCopaxone eningi kakhulu

Uma ucabanga ukuthi uthathe kakhulu lo muthi, shayela udokotela wakho. Ungashayela futhi i-American Association of Poison Control Centers ku-800-222-1222 noma usebenzise ithuluzi labo eliku-inthanethi. Kepha uma izimpawu zakho zinzima, shayela ku-911 noma uye egumbini lezimo eziphuthumayo eliseduze ngokushesha.

Imininingwane yobuchwepheshe yeCopaxone

Imininingwane elandelayo inikezwa odokotela nabanye ochwepheshe bezempilo.

Izinkomba

ICopaxone ivunyelwe ukwelapha lezi zimo kubantu abadala:

  • isifo esihlukaniswe ngokwasemtholampilo (i-CIS)
  • i-MS ebuyisa kabusha (RRMS)
  • i-MS yesibili eqhubekayo esebenzayo (SPMS)

Indlela yokusebenza

I-Copaxone iyindlela yokwelapha yokuguqula izifo equkethe i-acetate yesidakamizwa esisebenzayo i-glatiramer. Kuyisidakamizwa sokugomela emzimbeni, yize indlela yokusebenza kwayo ingaqondakali kahle.

I-Glatiramer acetate yimolekyuli yokwenziwa yamaprotheni efana nelinye lamaphrotheni emvelo atholakala ku-myelin. Kubukeka sengathi kusebenze amaseli we-T suppressor acindezela ukuphendula komzimba ku-myelin.

I-Glatiramer ngaleyo ndlela inciphisa ukuhlaselwa kwamasosha omzimba ku-myelin, okuholela ekubuyeleni emuva kwe-MS okumbalwa futhi kwehlise ukuqhubeka kwesifo.

I-Pharmacokinetics ne-metabolism

Inani elibalulekile leCopaxone lifakwa i-hydrolyzed kwezicubu ezingaphansi ngemuva kokuphathwa. Kokubili i-Copaxone eqinile ne-hydrolyzed ingena ekusakazweni kwe-lymphatic ne-systemic. Ingxenye yempilo yeCopaxone ayaziwa.

Izimo

I-Copaxone akumele isetshenziswe kubantu abane-allergies eyaziwayo ku-glatiramer acetate noma ku-mannitol.

Isitoreji

Gcina iCopaxone esiqandisini ezingeni lokushisa elingu-36 ° F kuye ku-46 ° F (2 ° C kuye ku-8 ° C). Gcina umuthi emaphaketheni asekuqaleni. Ungafrizi. Uma isipetu seCopaxone sesifriziwe, ungasisebenzisi.

Uma kudingeka, iCopaxone ingagcinwa ekamelweni lokushisa (59 ° F kuye ku-86 ° F / 15 ° C kuye ku-30 ​​° C) kuze kube yinyanga eyodwa.

Ukuzikhulula: IMedical News Namuhla yenze yonke imizamo yokuqinisekisa ukuthi yonke imininingwane ilungile ngokweqiniso, ibanzi, futhi isesikhathini. Kodwa-ke, le ndatshana akufanele isetshenziswe njengokungena esikhundleni solwazi nobungoti bochwepheshe bezokunakekelwa kwezempilo onelayisense. Kufanele uhlale uthintana nodokotela wakho noma omunye uchwepheshe wezokunakekelwa kwempilo ngaphambi kokuthatha noma imuphi umuthi. Imininingwane yezidakamizwa equkethwe lapha ingashintsha futhi ayihloselwe ukumboza konke ukusetshenziswa okungaba khona, izinkomba, izixwayiso, izexwayiso, ukuxhumana kwezidakamizwa, ukungezwani komzimba, noma imiphumela emibi. Ukungabikho kwezixwayiso noma olunye ulwazi lomuthi othile awukhombisi ukuthi inhlanganisela yezidakamizwa noma yezidakamizwa iphephile, iyasebenza, noma ilungele zonke iziguli noma konke ukusetshenziswa okuthile.

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