Ukuhlolwa kwe-Haptoglobin (HP)

-Delile

• Kuyini ukuhlolwa kwe-haptoglobin (HP)?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwe-haptoglobin?
• Kwenzekani ngesikhathi sokuhlolwa kwe-haptoglobin?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi ekuhlolweni kwe-haptoglobin?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kwe-haptoglobin?
• Izinkomba

Kuyini ukuhlolwa kwe-haptoglobin (HP)?

Lokhu kuhlolwa kukala inani le-haptoglobin egazini. I-Haptoglobin yiprotheni eyenziwe yisibindi sakho. Inamathela ohlotsheni oluthile lwe-hemoglobin. IHemoglobin yiprotheni kumaseli akho abomvu egazi athwala umoya-mpilo osuka emaphashini wakho uye kuwo wonke umzimba wakho. Iningi le-hemoglobin litholakala ngaphakathi kwamangqamuzana abomvu egazi, kodwa amanani amancane ajikeleza egazini. I-Haptoglobin ibophela i-hemoglobin egazini. Ngokubambisana, la maprotheni amabili aziwa njenge-haptoglobin-hemoglobin complex. Lesi sakhiwo sisuswa ngokushesha emgudwini wegazi sisuswe emzimbeni ngesibindi sakho.

Lapho amaseli abomvu egazi elinyazwa, akhipha i-hemoglobin eyengeziwe egazini. Lokho kusho ukuthi inqwaba ye-haptoglobin-hemoglobin complex izosuswa emzimbeni. I-haptoglobin ingashiya umzimba ngokushesha ukwedlula isibindi. Lokhu kubangela ukuthi amazinga akho egazi e-haptoglobin ehle. Uma amazinga akho e-haptoglobin ephansi kakhulu, kungaba uphawu lokuphazamiseka kwamaseli abomvu egazi, njenge-anemia.

Amanye amagama: amaprotheni abopha i-hemoglobin, HPT, Hp

Kusetshenziselwa ini?

Ukuhlolwa kwe-haptoglobin kuvame ukusetshenziselwa ukuxilonga i-hemolytic anemia. I-hemolytic anemia yisifo esenzeka lapho amangqamuzana akho abomvu egazi ebhujiswa ngokushesha kunokuba kungashintshwa amanye. Lokhu kuhlolwa kungasetshenziselwa nokubheka ukuthi ngabe olunye uhlobo lwe-anemia noma esinye isifo segazi sidala izimpawu zakho.

Kungani ngidinga ukuhlolwa kwe-haptoglobin?

Ungadinga lokhu kuhlolwa uma unezimpawu zokushoda kwegazi. Lokhu kufaka phakathi:

• Ukukhathala
• Isikhumba esiphaphathekile
• Ukuphelelwa umoya
• Ukushaya kwenhliziyo okusheshayo
• I-jaundice, isimo esidala ukuthi isikhumba namehlo akho abe phuzi
• Umchamo onombala omnyama

Ungase futhi udinge lokhu kuhlolwa uma ngabe ufakwe igazi. Ukuhlolwa kungenziwa ngokunye ukuhlolwa okubizwa nge-anti-globulin ngqo. Imiphumela yalokhu kuhlolwa ingakhombisa uma ngabe usabele kabi ekufakelweni igazi.

Kwenzekani ngesikhathi sokuhlolwa kwe-haptoglobin?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi noma yimaphi amalungiselelo akhethekile wokuhlolwa kwe-haptoglobin.

Ingabe zikhona izingozi ekuhlolweni kwe-haptoglobin?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Uma imiphumela yakho ikhombisa ukuthi amazinga akho e-haptoglobin angaphansi kunokujwayelekile, kungasho ukuthi unalezi zimo ezilandelayo:

• I-hemolytic anemia
• Isifo sesibindi
• Ukusabela ekumpontshelweni

Umhlinzeki wakho wezokunakekelwa kwempilo anga-oda ezinye izivivinyo zegazi ukusiza ukuxilonga Lokhu kufaka phakathi:

• Ukubalwa Kwe-Reticulocyte
• Ukuhlolwa kwe-hemoglobin
• Ukuhlolwa kwe-Hematocrit
• Ukuhlolwa kwe-Lactate Dehydrogenase
• Igazi Smear
• Qedela Ukubalwa Kwegazi

Lezi zivivinyo zingenziwa ngasikhathi sinye noma ngemuva kokuhlolwa kwakho kwe-haptoglobin.

Uma unemibuzo ngemiphumela yakho, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kwe-haptoglobin?

Izinga eliphakeme le-haptoglobin lingaba uphawu lwesifo sokuvuvukala. Izifo ezivuthayo yizinkinga zesistimu yomzimba ezingadala izinkinga ezinkulu zempilo. Kepha ukuhlolwa kwe-haptoglobin akuvamile ukusetshenziselwa ukuxilonga noma ukuqapha izimo ezihlobene namazinga aphezulu we-haptoglobin.

Izinkomba

1. I-American Society of Hematology [i-Intanethi]. IWashington D.C .: I-American Society of Hematology; c2020. Ukushoda kwegazi; [icashunwe ngo-2020 Mar 4]; [cishe izikrini ezi-3]. Kutholakala kusuka: http://www.hematology.org/Patients/Anemia
2. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. I-Haptoglobin; [kubuyekezwe i-2019 Sep 23; kukhonjiwe ngo-2020 Mar 4]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/ Kuitaoglobin
3. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. I-jaundice; [kubuyekezwe i-2019 Oct 30; kukhonjiwe ngo-2020 Mar 4]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/conditions/jaundice
4. IMaine Health [Inthanethi]. I-Portland (ME): Impilo yaseMaine; c2020. Izifo Zokuvuvukala / Ukuvuvukala; [icashunwe ngo-2020 Mar 4]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://mainehealth.org/services/autoimmune-diseases-rheumatology/infigueatory-diseases
5. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuhlolwa Kwegazi; [icashunwe ngo-2020 Mar 4]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
6. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. I-hemolytic anemia; [icashunwe ngo-2020 Mar 4]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/hemolytic-anemia
7. Shih AW, McFarlane A, Verhovsek M. Haptoglobin ukuhlolwa kwe-hemolysis: ukulinganisa nokuhumusha. Am J Hematol [Inthanethi]. 2014 Apr [icashunwe ngo-2020 Mar 4]; 89 (4): 443-7. Kutholakala kusuka: https://www.ncbi.nlm.nih.gov/pubmed/24809098
8. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2020. Ukuhlolwa kwegazi le-Haptoglobin: Ukubuka konke; [kubuyekezwe ngo-2020 Mar 4; kukhonjiwe ngo-2020 Mar 4]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/haptoglobin-blood-test
9. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2020. I-Health Encyclopedia: IHaptoglobin; [icashunwe ngo-2020 Mar 4]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid= Bapoglobin

Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.