Ingabe i-Psoriasis Ifa?

-Delile

• Ingabe kukhona ukuxhumana phakathi kofuzo ne-psoriasis?
• Yiziphi ezinye izinto ezinikela ku-psoriasis?
• Ngabe ukwelashwa kofuzo kungasetshenziswa ukwelapha i-psoriasis?
• Yelashwa kanjani ngokwesiko i-psoriasis?
• Ukudla okudlela endlini

Yini i-psoriasis futhi uyithola kanjani?

I-Psoriasis yisimo sesikhumba esivezwa yisikali esilumayo, ukuvuvukala nokubomvu. Imvamisa kwenzeka ekhanda, emadolweni, endololwaneni, ezandleni nasezinyaweni.

Ngokocwaningo oluthile, cishe abantu abayizigidi ezingama-7.4 e-United States babephila ne-psoriasis ngo-2013.

I-Psoriasis yisifo esizimele. Amaseli omzimba osegazini lakho aqaphela ngephutha amangqamuzana esikhumba asanda kukhiqizwa njengabahlaseli bakwamanye amazwe bese ewahlasela. Lokhu kungadala ukukhiqizwa ngokweqile kwamaseli amasha esikhumba ngaphansi kwesikhumba sakho.

Lawa maseli amasha afudukela phezulu futhi aphoqa amaseli wesikhumba akhona. Lokho kudala izikali, ukulunywa nokuvuvukala kwe-psoriasis.

Izakhi zofuzo cishe zidlala indima ethile. Funda ukuze ufunde kabanzi ngeqhaza lezakhi zofuzo ekwakhiweni kwe-psoriasis.

Ingabe kukhona ukuxhumana phakathi kofuzo ne-psoriasis?

I-Psoriasis ivame ukuvela phakathi kweminyaka yobudala eyi-15 nengama-35, ngokusho kweNational Psoriasis Foundation (NPF). Noma kunjalo, kungenzeka nganoma yisiphi isikhathi. Isibonelo, cishe izingane ezingama-20 000 ezineminyaka engaphansi kwengu-10 zitholakala zine-psoriasis njalo ngonyaka.

I-Psoriasis ingenzeka kubantu abangenawo umlando womndeni wesifo. Ukuba nelungu lomndeni elinalesi sifo kwandisa ingozi yakho.

• Uma omunye wabazali bakho ene-psoriasis, unethuba elingamaphesenti ayishumi lokulithola.
• Uma bobabili abazali bakho bane-psoriasis, ingozi yakho ingamaphesenti angama-50.
• Cishe ingxenye eyodwa kwezintathu yabantu abatholakala ukuthi bane-psoriasis banesihlobo esine-psoriasis.

Ososayensi abasebenza ngezimbangela zofuzo ze-psoriasis baqala ngokucabanga ukuthi isimo sibangelwa inkinga yesistimu yomzimba. esikhunjeni se-psoriatic kukhombisa ukuthi iqukethe inani elikhulu lamaseli omzimba akhiqiza ama-molecule wokuvuvukala aziwa ngokuthi ama-cytokines.

Isikhumba se-Psoriatic siqukethe nokuguqulwa kwezakhi zofuzo okwaziwa ngokuthi ama-alleles.

Ucwaningo lwakuqala ngawo-1980 lwaholela enkolelweni yokuthi i-allele eyodwa ingabhekana nokudlulisa lesi sifo ngemindeni.

kamuva wathola ukuthi ukutholakala kwalesi sihlava, I-HLA-Cw6, kwakunganele ukwenza umuntu ahlakulele lesi sifo. Okunye ukukhombisa ukuthi kusadingeka olunye ucwaningo ukuqonda kangcono ubudlelwane obuphakathi I-HLA-Cw6 kanye ne-psoriasis.

Ukusetshenziswa kwamasu athuthuke kakhulu kuholele ekuhlonzweni kwezifunda ezihlukene ezingama-25 ezintweni zofuzo zomuntu (i-genome) engahlotshaniswa ne-psoriasis.

Ngenxa yalokhu, izifundo zofuzo manje sezingasinika inkomba yobungozi bomuntu bokuthola i-psoriasis. Ukuxhumana phakathi kwezakhi zofuzo ezihambisana ne-psoriasis nesimo uqobo akukaqondakali kahle.

I-Psoriasis ifaka phakathi ukuxhumana phakathi kwamasosha akho omzimba nesikhumba sakho. Lokho kusho ukuthi kunzima ukwazi ukuthi yini imbangela nokuthi uyini umphumela.

Okutholakele okusha ocwaningweni lofuzo kunikeze ukuqonda okubalulekile, kodwa namanje asiqondi kahle ukuthi yini ebangela ukuqubuka kwe-psoriasis. Indlela enembile lapho i-psoriasis idluliselwa kusuka kumzali iye enganeni nayo ayiqondakali ngokuphelele.

Yiziphi ezinye izinto ezinikela ku-psoriasis?

Iningi labantu abane-psoriasis linokuqubuka ngezikhathi ezithile noma ukuqhuma okulandelwa yizikhathi zokuxolelwa. Cishe amaphesenti angama-30 abantu abane-psoriasis nabo babhekana nokuvuvukala kwamalunga afana nesifo samathambo. Lokhu kubizwa ngokuthi yi-psoriatic arthritis.

Izici zemvelo ezingadala ukuqala kwe-psoriasis noma ukuvuleka zifaka:

• ukucindezeleka
• isimo sezulu esibandayo nesomile
• Ukutheleleka nge-HIV
• izidakamizwa ezifana ne-lithium, i-beta-blockers, kanye nemithi elwa namagciwane
• ukuhoxiswa kwama-corticosteroids

Ukulimala noma ukuhlukumezeka engxenyeni yesikhumba sakho kwesinye isikhathi kungaba yisiza se-psoriasis flare-up. Ukutheleleka nakho kungaba yisiqalo. I-NPF iphawula ukuthi ukutheleleka, ikakhulukazi i-strep throat kubantu abasha, kubikwa njengesiqalo sokuqala kwe-psoriasis.

Ezinye izifo zivame kakhulu kubantu abane-psoriasis kunabantu abaningi. Kokunye ukuhlola kwabesifazane abane-psoriasis, cishe amaphesenti ayi-10 ababambiqhaza nawo asethule isifo samathumbu esivuthayo njengesifo sikaCrohn noma isifo sezilonda.

Abantu abane-psoriasis banezigameko ezikhuphukile ze:

• I-lymphoma
• Isifo senhliziyo
• ukukhuluphala ngokweqile
• thayipha 2 sikashukela
• isifo se-metabolic syndrome
• ukudana nokuzibulala
• ukuphuza utshwala
• ukubhema

Ngabe ukwelashwa kofuzo kungasetshenziswa ukwelapha i-psoriasis?

Ukwelashwa kwe-Gene okwamanje akutholakali njengokwelashwa, kodwa kukhona ukunwetshwa kocwaningo ngezimbangela zofuzo ze-psoriasis. Kokunye kokutholwa okuningi okuthembisayo, abacwaningi bathole ukuguqulwa kohlobo olungajwayelekile oluxhunyaniswe ne-psoriasis.

Ukuguqulwa kwezakhi zofuzo kwaziwa njenge IKHADI14. Lapho kuvezwa isisusa semvelo, njengokutheleleka, lokhu kuguquka kuveza i-plaque psoriasis. I-plaque psoriasis iyindlela evame kakhulu yesifo. Lokhu kutholakala kusizile ukusungula ukuxhumana kwe- IKHADI14 ukuguquka kwe-psoriasis.

Laba bacwaningi abafanayo nabo bathole i- IKHADI14 uguquko lukhona emindenini emibili emikhulu ebinamalungu amaningi omndeni ane-plaque psoriasis ne-psoriatic arthritis.

Lokhu kungenye yezimbalwa zokutholwa kwakamuva okunesithembiso sokuthi uhlobo oluthile lokwelashwa kofuzo ngelinye ilanga luzokwazi ukusiza abantu abaphila ne-psoriasis noma i-psoriatic arthritis.

Yelashwa kanjani ngokwesiko i-psoriasis?

Ezimweni eziphansi ukuya kokulingene, odokotela besikhumba bavame ukuncoma ukwelashwa okunezihloko njengokhilimu noma amafutha. Lokhu kungafaka:

• anthralin
• itela lamalahle
• i-salicylic acid
• tazarotene
• ama-corticosteroids
• uvithamini D

Uma unesifo esibi kakhulu se-psoriasis, udokotela wakho angakunika i-phototherapy kanye nemithi esezingeni eliphakeme kakhulu ye-systemic noma ye-biologic, ethathwe ngomlomo noma ngomjovo.

Ukudla okudlela endlini

Abaphenyi bathole ukuxhumana phakathi kwe-psoriasis ne-genetics. Ukuba nomlando womndeni waleso simo kukhulisa ubungozi bakho. Ucwaningo oluningi luyadingeka ukuqonda ngokugcwele ifa le-psoriasis.