I-Prednisolone: ​​yenzelwe ini, imiphumela emibi nokuthi ungayithatha kanjani

-Delile

• Yenzelwe ini
• Ungathatha kanjani
• 1. 5 noma 20 mg amaphilisi
• 2. 3 mg / ml noma isiraphu engu-1 mg / ml
• 3. Isixazululo se-11 mg / mL iconsi
• Okuqhamuka uma udla imishanguzo
• Izimo
• Uyini umehluko phakathi kwe-prednisolone ne-prednisone?

I-Prednisolone iyi-steroidal anti-inflammatory, ekhonjiswe ekwelapheni izinkinga ezifana ne-rheumatism, ukushintsha kwama-hormone, i-collagen, i-allergies nezinkinga zesikhumba nezamehlo, ukuvuvukala okujwayelekile, ukuphazamiseka kwegazi nezinkinga, ukuphefumula, izinkinga zesisu kanye nezinkinga zezinzwa kanye nezifo. Ngaphezu kwalokho, leli thuluzi lingasetshenziswa nasekwelapheni umdlavuza.

Lo muthi utholakala ngohlobo lwamaphilisi, ukumiswa ngomlomo noma amaconsi futhi ungathengwa emakhemisi, lapho kwethulwa incwadi kadokotela.

Yenzelwe ini

I-Prednisolone yisidakamizwa esisebenza njenge-anti-inflammatory kanye ne-immunosuppressant, ekhonjiswa ekwelapheni izifo lapho kuvela khona izinqubo zokuvuvukala nokuzimela, ukwelashwa kwezinkinga ze-endocrine futhi ezihambisana nezinye izidakamizwa zokwelapha umdlavuza. Ngakho-ke, i-prednisolone ikhonjisiwe ezimweni ezilandelayo:

• Izinkinga ze-Endocrine, njengokuntuleka kwe-adrenocortical, i-congenital adrenal hyperplasia, i-non-suppurative thyroiditis kanye ne-hypercalcemia ehambisana nomdlavuza;
• I-Rheumatism, njenge-psoriatic noma i-rheumatoid arthritis, i-ankylosing spondylitis, i-bursitis, i-tenosynovitis engacacisanga kahle, i-acute gouty arthritis, i-post-traumatic osteoarthritis, i-osteoarthritic synovitis ne-epicondylitis;
• Ama-Collagenoses, ezimweni ezithile ze-systemic lupus erythematosus kanye ne-acute rheumatic carditis;
• Izifo zesikhumba, njenge-pemphigus, i-dermatitis ethile, i-mycosis ne-psoriasis enamandla;
• Ukungezwani komzimba, njenge-rhinitis yokungezwani, i-contact kanye ne-atopic dermatitis, izifo ze-serum kanye ne-hypersensitivity reaction to drug;
• Izifo zamehlo, ezinjengezilonda ezingekho emzimbeni ze-corneal ulcers, i-ophthalmic herpes zoster, ukuvuvukala kwengxenye yangaphakathi, ukusakazeka kwe-choroiditis kanye ne-posterior uveitis, i-ophthalmia enozwelo, i-allergen conjunctivitis, i-keratitis, i-chorioretinitis, i-optic neuritis, i-iritis ne-iridocyclitis;
• Izifo zokuphefumula, njenge-sarcoidosis enezimpawu, i-Löefler syndrome, i-berylliosis, ezinye izifo zesifo sofuba, i-aspiration pneumonitis ne-asthma ye-bronchial;
• Ukuphazamiseka kwegazi, njenge-idiopathic thrombocytopenic purpura ne-thrombocytopenia yesibili kubantu abadala, bathola i-hemolytic anemia, i-erythrocytic anemia ne-erythroid anemia;
• Umdlavuza, ekwelapheni okunciphisayo kwama-leukemias nama-lymphomas.

Ngaphezu kwalokho, i-prednisolone ingasetshenziselwa ukwelapha ukuqina okukhulu kwe-multiple sclerosis, ukunciphisa ukuvuvukala ezimweni ze-idiopathic nephrotic syndrome kanye ne-lupus erythematosus nokugcina isiguli esine-ulcerative colitis noma i-enteritis yesifunda.

Ungathatha kanjani

Umthamo we-prednisolone wehluka kakhulu ngokwesisindo, ubudala, izifo okufanele zilashwe kanye nefomu lezemithi futhi kufanele njalo kunqunywe udokotela.

1. 5 noma 20 mg amaphilisi

• Abantu abadala: umthamo wokuqala uyahluka kusuka ku-5 kuye ku-60 mg ngosuku, okulingana ne-1 5 mg tablet noma amaphilisi ama-3 20 mg.
• Izingane: umthamo wokuqala uyahluka kusuka ku-5 kuye ku-20 mg ngosuku, okulingana ne-1 5 mg tablet noma i-1 20 mg tablet.

Umthamo kufanele wehliswe kancane kancane lapho umuthi unikezwa ngaphezu kwezinsuku ezimbalwa. Amaphilisi kufanele agwinywe ephelele, kanye nengilazi yamanzi, ngaphandle kokuphuka noma ukuhlafuna.

2. 3 mg / ml noma isiraphu engu-1 mg / ml

• Abantu abadala: amanani anconyiwe asukela ku-5 kuye ku-60 mg ngosuku;
• Izingane Nezingane: isilinganiso esinconywayo siyehluka kusuka ku-0.14 kuye ku-2 mg nge-1 kg ngayinye yesisindo sengane ngosuku, sehlukaniswe saba ukuphathwa kwansuku zonke okungu-3 kuye ku-4;

Ivolumu ezolinganiswa incike ekugxileni kwesisombululo somlomo, njengoba kunezethulo ezimbili ezihlukene. Umthamo kufanele wehliswe kancane kancane lapho umuthi unikezwa ngaphezu kwezinsuku ezimbalwa.

3. Isixazululo se-11 mg / mL iconsi

• Abantu abadala: amanani anconyiwe asukela ku-5 kuye ku-60 mg ngosuku, alingana namaconsi ayi-9 noma amaconsi ayi-109 ngosuku.
• Izingane: umthamo onconywayo uyehluka kusuka ku-0.14 kuye ku-2 mg nge-1 kg ngayinye yesisindo sengane, elawulwa izikhathi ezi-1 kuye kwezingu-4 ngosuku.

Iconsi ngalinye lilingana no-0.55 mg we-prednisolone. Umthamo kufanele wehliswe kancane kancane lapho umuthi unikezwa ngaphezu kwezinsuku ezimbalwa.

Umthamo onconyiwe nobude besikhathi sokwelashwa ngePrednisolone kufanele kuboniswe ngudokotela, ngoba lokhu kuncike enkingeni ezokwelashwa, iminyaka nempendulo yesiguli ekwelashweni.

Okuqhamuka uma udla imishanguzo

Imiphumela emibi kakhulu engahle yenzeke ngesikhathi sokwelashwa nge-prednisolone ukukhushulwa kwesifiso sokudla, ukugaya ukudla okungalungile, i-peptic ulcer, i-pancreatitis kanye ne-ulcerative esophagitis, uvalo, ukukhathala nokuqwasha.

Ngaphezu kwalokho, ukungezwani komzimba, ukuphazamiseka kwamehlo, njenge-cataract, i-glaucoma, i-exophthalmos kanye nokuqina kokutheleleka kwesibili ngesikhunta noma ngamagciwane wamehlo, ukunciphisa ukubekezelelana kwama-carbohydrate, ukubonakaliswa kwesifo sikashukela esivele sakhula kanye nesidingo esengeziwe se-insulin noma ama-ejenti omlomo we-hypoglycemic. abanesifo sikashukela.

Ukwelashwa ngamanani aphezulu ama-corticosteroids kungadala ukwanda okuphawulekayo kwama-triglycerides egazini.

Bona okuningi ngemiphumela emibi ye-corticosteroids.

Izimo

I-Prednisolone iyaphikiswa kubantu abanezifo zesikhunta zesistimu noma izifo ezingalawulwa kanye neziguli ezinokungezwani komzimba ne-prednisolone noma yiziphi izingxenye zefomula.

Ngaphezu kwalokho, lo muthi akufanele usetshenziswe ngabesifazane abakhulelwe noma abancelisayo, ngaphandle kwalapho kunconywa udokotela.

Uyini umehluko phakathi kwe-prednisolone ne-prednisone?

I-Prednisone iyi-prodrug ye-prednisolone, okusho ukuthi, i-prednisone yinto engasebenzi, ukuze ikwazi ukusebenza kufanele iguqulwe esibindini ibe yi-prednisolone, ukuze yenze isenzo sayo.

Ngakho-ke, uma umuntu efaka i-prednisone noma i-prednisolone, isenzo esenziwa umuthi sizofana, ngoba i-prednisone iyaguqulwa futhi yenziwe isebenze, esibindini, ibe yi-prednisolone. Ngalesi sizathu, i-prednisolone inezinzuzo eziningi kubantu abanezinkinga zesibindi, njengoba ingadingi ukuguqulwa esibindini ukuze isebenzise umsebenzi emzimbeni.