Ucwaningo Olwesabisa Kakhulu Lwesifo Sikashukela lowe-2015

-Delile

• 1. Kuyasiza ukuyeka ukubhema.
• 2. Simbe idatha ukukhomba ama-subtypes.
• 3. Ukudana nesifo sikashukela: Yikuphi okwafika kuqala?
• 4. Ngabe isengezo sokudla okunobuthi singasiza ekwelapheni isifo sikashukela?
• 5. Isoda iyingozi ngisho nasezinhlotsheni zomzimba ezincane.

Isifo sikashukela yisifo se-metabolic esibonakala ngamazinga aphezulu eshukela egazi ngenxa yokushoda noma ukunciphisa inani le-insulin, ukungakwazi komzimba ukusebenzisa i-insulin ngendlela efanele, noma kokubili. Ngokusho kwe-, cishe abantu abangamaphesenti ayisishiyagalolunye emhlabeni jikelele banesifo sikashukela, kanti lesi sifo sibulala cishe abantu abayizigidi eziyi-1.5 ngonyaka.

Kunezinhlobo ezimbili ezinkulu zesifo sikashukela. Uhlobo lwesifo sikashukela sohlobo 1 yisifo sokuzilimaza esihlasela kakhulu izingane nentsha esikhulile, futhi sithinta abantu ababalelwa ezigidini eziyi-1.25 e-United States. Cishe abantu abayizigidi ezingama-28 e-United States bane-type 2 yesifo sikashukela. Imvamisa ikhula ngokuhamba kwesikhathi empilweni, yize abantu abasha beya ngokuya betholakala benesifo sikashukela sohlobo 2. Kutholakala kakhulu kubantu abakhuluphele ngokweqile. Zombili izinhlobo zesifo sikashukela zingasebenza emindenini.

Alikho ikhambi lesifo sikashukela, kepha lingalawulwa ngemithi nangezinguquko ezinkulu zokuphila. Ukwehluleka ukuphatha isifo sikashukela kunemiphumela emibi. Isifo sikashukela sidala ukungaboni, izinkinga zemizwa, isifo senhliziyo, futhi singakhuphula ubungozi be-Alzheimer's. Kungadala nokuhluleka kwezinso nokulimala kwezinyawo okukhulu ngokwanele ukudinga ukunqunywa.

Eminyakeni engama-30 edlule, abantu abanesifo sikashukela e-United States, lapho manje sekuyimbangela yesi-7 yokufa kwabantu. Ngenkathi amazinga esifo sikashukela ekhuphuka kuwo wonke amaqembu ezinhlanga, kuvame kakhulu kubantu base-Afrika-baseMelika kanye nabomdabu baseMelika.

Ukuthola ikhambi lesifo sikashukela kubalulekile. Kuze kube yilapho siyitholile, ukwenza ngcono ukuqwashisa nokusiza abantu asebevele benesifo sikashukela ukuphatha kangcono isimo sabo kubalulekile. Funda uqhubeke ufunde ngokwenzeka ngo-2015 okusisondeze kulezo zinhloso.

1. Kuyasiza ukuyeka ukubhema.

Ngokusho kwalaba, abantu ababhema ugwayi basengozini ephakathi kwamaphesenti angama-30 nengama-40 okuba nesifo sikashukela sohlobo 2. Futhi ababhemayo asebevele benesifo sikashukela kungenzeka babe sengozini yezinkinga ezinkulu zempilo, njengesifo senhliziyo, i-retinopathy, nokusakazeka kahle komzimba.

2. Simbe idatha ukukhomba ama-subtypes.

Sicabanga ngesifo sikashukela njengesifo esisodwa, kepha abantu abanaso babhekana nokwehluka okuningi ngohlobo nobukhulu bezimpawu. Lokhu kwehlukahlukana kubizwa ngokuthi ama-subtypes, kanti isifundo esisha esivela kubacwaningi e-Icahn School of Medicine eNtabeni iSinayi sinikeze ukuqonda okujulile ngazo. Abaphenyi baqoqa idatha engaziwa kusuka kumashumi ezinkulungwane zamarekhodi ezokwelapha ze-elekthronikhi, bekhuthaza ukusebenza kahle kwemithi yokwelapha ehlinzeka ngokuhlukahluka ngakunye esikhundleni sendlela elingana.

3. Ukudana nesifo sikashukela: Yikuphi okwafika kuqala?

Kujwayelekile ukuthi umuntu abe nesifo sikashukela kanye nokudangala, kepha ubudlelwano bebulokhu buyinkukhu kanye neqanda. Ochwepheshe abaningi bakholelwa ukuthi isifo sikashukela yiso esibhebhethekisayo. Kepha ucwaningo lwakamuva olusuka luthi ubudlelwano bungangena kuzo zombili izinhlangothi. Bavumbulule izinto ezithile zomzimba zesimo ngasinye ezingathinta, noma ziphume nakwezinye. Isibonelo, ngenkathi isifo sikashukela siguqula ukwakheka kobuchopho nokusebenza ngezindlela ezingaholela ekukhuleni kokudangala, ama-antidepressants angakhuphula ubungozi bokuhlaselwa yisifo sikashukela.

4. Ngabe isengezo sokudla okunobuthi singasiza ekwelapheni isifo sikashukela?

I-DNP, noma i-2,4-Dinitrophenol, iyikhemikhali ephikisanayo enemiphumela emibi engaba nobuthi. Yize ibhalwe ukuthi "ayikulungele ukusetshenziswa komuntu" e-United States nase-U.K., Ihlala itholakala kabanzi ngefomu lokungezelela.

Yize kuyingozi ngobuningi, ucwaningo lwamuva lubheke ukuthi kungenzeka ukuthi inguqulo ekhishwe ngokulawulwa ye-DNP ingahlehlisa isifo sikashukela kumagundane. Lokhu bekungenxa yokuthi kuphumelele ekwelashweni kwangaphambilini kwelabhorethri kwesifo esingenalo utshwala esinamafutha nokuqina kwe-insulin, okuyisandulela sikashukela. Uhlobo olukhishwe ngokulawulwa, olubizwa ngeCRMP, lutholakale lungelona ubuthi kumagundane, kanti abacwaningi bathi lungaphepha futhi lusebenze kahle ekulawuleni isifo sikashukela ebantwini.

5. Isoda iyingozi ngisho nasezinhlotsheni zomzimba ezincane.

Siyazi ukuthi kukhona ukuxhumana phakathi kohlobo 2 sikashukela nokukhuluphala noma ukukhuluphala ngokweqile. Lezi zinkinga zesisindo zivame ukuvela ekudleni okunoshukela omningi. Yize lokho kungaholela ekutheni uphethe ngokuthi ngabantu abakhuluphele ngokweqile kuphela okufanele baziqhelelanise nama-sodas, ucwaningo olusha lukhombisa ukuthi lezi ziphuzo zibeka noma ngubani engcupheni, noma ngabe zingakanani usayizi wazo.

Ngokuya ngocwaningo olukhona, ukuphuza iziphuzo ezinoshukela eziningi - kufaka phakathi i-soda nejusi yezithelo - kuhlotshaniswa kahle nohlobo lwesifo sikashukela sohlobo lwe-2, kungakhathalekile isisindo. Abaphenyi bathola ukuthi lezi ziphuzo zifaka isandla kumaphesenti aphakathi kwamane kuya kwayi-13 ohlobo lwesifo sikashukela e-United States.