Ukuhlolwa Kwegazi le-SHBG

-Delile

• Kuyini ukuhlolwa kwegazi kwe-SHBG?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwegazi le-SHBG?
• Kwenzekani ngesikhathi sokuhlolwa kwegazi le-SHBG?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi esivivinyweni?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwegazi le-SHBG?
• Izinkomba

Kuyini ukuhlolwa kwegazi kwe-SHBG?

Lokhu kuhlolwa kukala amazinga e-SHBG egazini lakho. I-SHBG imele i-hormone ebopha i-globulin. Yiprotheni elenziwe yisibindi futhi linamathela kuma-hormone ezocansi atholakala kwabesilisa nabesifazane. Lawa mahomoni yi:

• I-testosterone, i-hormone enkulu yocansi emadodeni
• I-Dihydrotestosterone (DHT), enye i-hormone yobulili besilisa
• I-Estradiol, uhlobo lwe-estrogen, i-hormone enkulu yocansi kwabesifazane

I-SHBG ilawula ukuthi mangaki la mahomoni ahanjiswa ezicutshini zomzimba. Yize i-SHBG inamathela kuwo womathathu la mahomoni, ukuhlolwa kwe-SHBG kusetshenziselwa ukubheka i-testosterone. Amazinga e-SHBG angakhombisa uma kune-testosterone eningi kakhulu noma encane kakhulu esetshenziswa ngumzimba.

Amanye amagama: i-testosterone-estrogen ebopha i-globulin, i-TeBG

Kusetshenziselwa ini?

Ukuhlolwa kwe-SHBG kuvame ukusetshenziselwa ukuthola ukuthi yimalini i-testosterone eya ezicutshini zomzimba. Amazinga e-testosterone angalinganiswa ekuhlolweni okuhlukile okubizwa nge-testosterone ephelele. Lokhu kuhlolwa kukhombisa ukuthi ingakanani i-testosterone esemzimbeni, kodwa hhayi ukuthi isetshenziswa kangakanani umzimba.

Kwesinye isikhathi ukuhlolwa okuphelele kwe-testosterone kwanele ukwenza ukuxilongwa. Kodwa abanye abantu banezimpawu ze-hormone eningi kakhulu noma encane kakhulu imiphumela yemiphumela yokuhlolwa kwe-testosterone engakwazi ukuyichaza. Kulezi zimo, ukuhlolwa kwe-SHBG kungahle ku-tshelwe ukuthi kuhlinzeke imininingwane ethe xaxa mayelana nokuthi ingakanani i-testosterone etholakalayo emzimbeni.

Kungani ngidinga ukuhlolwa kwegazi le-SHBG?

Ungadinga lokhu kuhlolwa uma unezimpawu zamazinga we-testosterone angajwayelekile, ikakhulukazi uma ukuhlolwa okuphelele kwe-testosterone kungakwazi ukuchaza izimpawu zakho. Kwabesilisa, kuyalwa kakhulu uma kunezimpawu zamazinga aphansi e-testosterone. Kwabesifazane, kuyalwe kakhulu uma kunezimpawu zamazinga aphezulu e-testosterone.

Izimpawu zamazinga aphansi e-testosterone emadodeni afaka:

• Ukushayela ocansini okuphansi
• Kunzima ukuthola ukwakhiwa
• Izinkinga zokuzala

Izimpawu zamazinga aphezulu e-testosterone kwabesifazane afaka:

• Ukukhula kwezinwele okweqile komzimba nobuso
• Ukujula kwezwi
• Ukungahambi kahle esikhathini
• Izinduna
• Ukuzuza kwesisindo
• Izinkinga zokuzala

Kwenzekani ngesikhathi sokuhlolwa kwegazi le-SHBG?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi amalungiselelo akhethekile wokuhlolwa kwe-SHBG.

Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Uma imiphumela yakho ikhombisa ukuthi amazinga akho e-SHBG aphansi kakhulu, kungasho ukuthi iphrotheni alizinamathiseli ku-testosterone eyanele. Lokhu kuvumela i-testosterone enganamathele ngaphezulu ukuthi itholakale ohlelweni lwakho. Kungadala ukuthi i-testosterone eningi kakhulu iye ezicutshini zomzimba wakho.

Uma amazinga akho e-SHBG ephezulu kakhulu, kungasho ukuthi iphrotheni lizihlanganisa ne-testosterone eningi kakhulu. Ngakho-ke i-hormone encane iyatholakala, futhi izicubu zakho kungenzeka ukuthi azitholi i-testosterone eyanele.

Uma amazinga akho e-SHBG ephansi kakhulu, kungaba uphawu lwe:

• I-Hypothyroidism, isimo lapho umzimba wakho ungenzi khona ama-hormone e-thyroid anele
• Thayipha 2 sikashukela
• Ukusetshenziswa ngokweqile kwemithi ye-steroid
• I-Cushing’s syndrome, isimo lapho umzimba wakho wenza khona i-hormone eningi kakhulu ebizwa nge-cortisol
• Kwabesilisa, kungasho umdlavuza wamasende noma izindlala ze-adrenal. Izindlala ze-Adrenal zitholakala ngaphezu kwezinso futhi zisiza ukulawula ukushaya kwenhliziyo, umfutho wegazi, neminye imisebenzi yomzimba.
• Kwabesifazane, kungasho ukuthi i-polycystic ovary syndrome (i-PCOS). I-PCOS yisifo esivamile sehomoni esithinta abesifazane abazalayo. Ingesinye sezimbangela ezihamba phambili zokungazali kwabesifazane.

Uma amazinga akho e-SHBG ephezulu kakhulu, kungaba uphawu lwe:

• Isifo sesibindi
• I-Hyperthyroidism, isimo lapho umzimba wakho wenza khona i-hormone yegilo eningi kakhulu
• Izinkinga zokudla
• Kwabesilisa, kungasho inkinga ngamasende noma ngendlala ye-pituitary. Indlala ye-pituitary itholakala ngaphansi kobuchopho futhi ilawula imisebenzi eminingi yomzimba.
• Kwabesifazane, kungasho inkinga ngendlala ye-pituitary, noma isifo i-Addison. Isifo i-Addison yisifo lapho izindlala ze-adrenal zingakwazi ukwenza ngokwanele amahomoni athile.

Umhlinzeki wakho wokunakekelwa kwezempilo anga-oda izivivinyo ezengeziwe ezifana nokuhlolwa okuphelele kwe-testosterone noma kwe-estrogen ukusiza ukwenza ukuxilongwa. Uma unemibuzo mayelana nemiphumela yakho, khuluma nomhlinzeki wakho.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwegazi le-SHBG?

Amazinga e-SHBG ngokuvamile aphakeme ezinganeni zabo bobabili ubulili, ngakho-ke isivivinyo ngaso sonke isikhathi sisetshenziselwa abantu abadala.

Izinkomba

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