Izinketho zokwelashwa ze-Idiopathic Pulmonary Fibrosis (IPF)

-Delile

• Ukwelashwa kokuqala kwe-idiopathic pulmonary fibrosis (IPF)
• Yiziphi izinhlobo zemithi ezitholakalayo?
• I-Pirfenidone
• UNintedanib
• Amaphilisi e-Corticosteroid
• I-N-Acetylcysteine ​​(ngomlomo noma nge-aerosolized)
• Ukwelashwa kwe-oksijeni kwe-IPF
• Ukufakelwa kwamaphaphu kwe-IPF
• Ukwelashwa kokuhlola
• Yiziphi izinhlobo zokungenelela okungezona ezokwelapha ezingasiza?
• Yehlisa isisindo noma ugcine isisindo esinempilo
• Yeka ukubhema
• Thola imigomo minyaka yonke
• Gada amazinga akho oksijini
• Bamba iqhaza ekuvuselelweni kwamaphaphu
• Yiziphi izinhlobo zamaqembu okusekela ezitholakalayo?
• Uyini umbono wabantu abane-IPF?

I-Idiopathic pulmonary fibrosis (IPF) yisifo samaphaphu esibangelwa ukwakheka kwezicubu ezibomvu ngaphakathi kwamaphaphu.

Isibazi siya ngokuya siba sibi. Lokhu kwenza kube nzima kakhulu ukuphefumula nokugcina amazinga anele oksijini egazini.

Amazinga e-oxygen aphansi aqhubekayo abangela izinkinga ezahlukahlukene emzimbeni wonke. Uphawu oluyinhloko ukuphelelwa umoya, okungaholela ekukhatheni nakwezinye izinkinga.

Ukwelashwa kokuqala kwe-idiopathic pulmonary fibrosis (IPF)

I-IPF yisifo esiqhubekayo, okusho ukuthi izimpawu ziba zimbi ngokuhamba kwesikhathi, futhi ukwelashwa kusenesikhathi kubalulekile. Okwamanje alikho ikhambi le-IPF, futhi izibazi azikwazi ukuhlehliswa noma zisuswe.

Kodwa-ke, kukhona ukwelashwa okusiza uku:

• ukusekela indlela yokuphila enempilo
• phatha izimpawu
• ukuqhubeka kwesifo kancane
• gcina ikhwalithi yempilo

Yiziphi izinhlobo zemithi ezitholakalayo?

Izinketho zokwelashwa zibandakanya imishanguzo emibili evunyelwe ye-antifibrotic (anti-scarring).

I-Pirfenidone

I-Pirfenidone yisidakamizwa esinqanda i-antifibrotic esinganciphisa ukuqhubeka kokulimala kwezicubu zamaphaphu. Inezinto zokulwa nokulwa nezifo, anti-inflammatory, kanye ne-antioxidant.

IPirfenidone ixhunywe ku:

• amazinga okusinda athuthukisiwe

UNintedanib

INintedanib ngesinye isidakamizwa esinqanda imishanguzo esifana ne-pirfenidone esiboniswe ekuhlolweni kwemitholampilo ukubambezela ukuqhubeka kwe-IPF.

Kubantu abaningi abane-IPF abangenaso isifo sesibindi esiyimbangela, i-pirfenidone noma i-nintedanib yizona zindlela zokwelashwa ezivunyelwe.

Idatha yamanje ayinele ukukhetha phakathi kwe-pirfenidone ne-nintedanib.

Lapho ukhetha phakathi kwalokhu okubili, izintandokazi zakho nokubekezelelana kufanele kubhekwe, ikakhulukazi maqondana nemiphumela emibi engaba khona.

Lokhu kufaka phakathi ukuhanjiswa kohudo nokusebenza kwesibindi ngokungajwayelekile nge-nintedanib kanye nesicanucanu kanye nokuqubuka nge-pirfenidone.

Amaphilisi e-Corticosteroid

I-Corticosteroids, njenge-prednisone, inganciphisa ukuvuvukala emaphashini kodwa ayiseyona ingxenye ejwayelekile yesondlo esijwayelekile sabantu abane-IPF njengoba kungakhonjiswanga ukuthi iyasebenza noma iphephile.

I-N-Acetylcysteine ​​(ngomlomo noma nge-aerosolized)

I-N-Acetylcysteine ​​iyi-antioxidant efundelwe ukusetshenziswa kubantu okutholwe ukuthi bane-IPF. Imiphumela evela ekuhlolweni kwemitholampilo ixubile.

Ngokufana ne-corticosteroids, i-N-Acetylcysteine ​​ayisasetshenziswa kakhulu njengengxenye yesondlo esijwayelekile.

Ezinye izindlela zokwelashwa ezingaba khona zifaka:

• iproton pump inhibitors, okuvimba isisu ekukhiqizeni i-asidi (ukuphefumula i-asidi yesisu ngokweqile kuxhunyiwe futhi kungafaka isandla ku-IPF)
• izivikeli mzimba, njenge-mycophenolate ne-azathioprine, engelapha izifo ezizimele zomzimba futhi isize ukuvimbela ukwenqatshwa kwamaphaphu atshaliwe

Ukwelashwa kwe-oksijeni kwe-IPF

Udokotela wakho futhi angancoma ezinye izindlela zokwelashwa. Ukwelashwa kwe-oxygen kungakusiza uphefumule kalula, ikakhulukazi ngesikhathi sokuzivocavoca kanye neminye imisebenzi.

Okwengeziwe oksijini kunganciphisa izinkinga ezihlobene namazinga aphansi oksijini egazini njengokukhathala esikhathini esifushane.

Ezinye izinzuzo zisacwaningwa.

Ukufakelwa kwamaphaphu kwe-IPF

Ungase ube ukhetho lokufakelwa kwamaphaphu. Ukufakelwa kwamaphaphu kwake kwabekelwa abamukeli abancane. Kodwa manje zivame ukunikezwa kubantu abaneminyaka engaphezu kwengama-65 abaphilile ngenye indlela.

Ukwelashwa kokuhlola

Kunezindlela zokwelashwa ezintsha ezingaba khona ze-IPF ngaphansi kophenyo.

Unenketho yokufaka ezinhlobonhlobo zezilingo zemitholampilo ezifuna ukuthola izindlela ezintsha zokuvimbela, ukuxilonga, nokwelapha izifo ezahlukahlukene zamaphaphu, kufaka phakathi i-IPF.

Ungathola izivivinyo zomtholampilo eCentreWatch, elandelela ucwaningo olukhulu ngezihloko eziseshekayo.

Lokhu kunikeza imininingwane yokuthi izivivinyo zomtholampilo zisebenza kanjani, ubungozi nezinzuzo, nokuningi.

Yiziphi izinhlobo zokungenelela okungezona ezokwelapha ezingasiza?

Izinguquko zendlela yokuphila nezinye izindlela zokwelapha ezingakusizi zingakusiza uhlale uphilile futhi uthuthukise ikhwalithi yempilo yakho.

Nazi ezinye izincomo.

Yehlisa isisindo noma ugcine isisindo esinempilo

Khuluma nodokotela wakho ngezindlela ezinempilo zokunciphisa noma zokuphatha isisindo sakho. Ukukhuluphala ngokweqile kwesinye isikhathi kungaba nomthelela ezinkingeni zokuphefumula.

Yeka ukubhema

Ukubhema kungenye yezinto ezimbi kakhulu ongayenza emaphashini akho. Manje, kunanini ngaphambili, kubalulekile ukuyeka lo mkhuba ungadala umonakalo omkhulu.

Thola imigomo minyaka yonke

Khuluma nodokotela wakho ngemikhuhlane yonyaka kanye nemithi yokugomela i-pneumonia kanye nokukhwehlela (pertussis). Lokhu kungasiza ukuvikela amaphaphu akho ekutheleleni nasekulimaleni okuqhubekayo.

Gada amazinga akho oksijini

Sebenzisa i-oximeter yekhaya eshaywayo ukuqapha ukusuthiswa komoya-mpilo wakho. Imvamisa umgomo ukuba namazinga e-oxygen okungenani noma ngaphezulu kwamaphesenti angama-90.

Bamba iqhaza ekuvuselelweni kwamaphaphu

Ukuvuselelwa kwamapulmonary wuhlelo olunezici ezahlukahlukene oluye lwaba yisisekelo sokwelashwa kwe-IPF. Ihlose ukwenza ngcono impilo yansuku zonke yabantu abane-IPF kanye nokunciphisa ukuphefumula okumbili ekuphumuleni nasekuzivocavoca umzimba.

Izici ezibalulekile zifaka:

• ukuphefumula nokulolonga umzimba
• ukuphathwa kwengcindezi nokukhathazeka
• ukusekelwa ngokomzwelo
• ukwelulekwa ngokudla okunempilo
• imfundo yesineke

Yiziphi izinhlobo zamaqembu okusekela ezitholakalayo?

Kukhona nezinhlelo zokusekela. Lokhu kungenza umehluko omkhulu kwikhwalithi yakho yempilo nombono wakho maqondana nokuphila ne-IPF.

I-Pulmonary Fibrosis Foundation ine-database engasesheka yamaqembu osizo endawo kanye nemiphakathi eminingi eku-inthanethi.

Lezi zinsizakusebenza zibaluleke kakhulu njengoba wamukela ukuxilongwa kwakho nezinguquko ezingaletha empilweni yakho.

Uyini umbono wabantu abane-IPF?

Yize lungekho ikhambi le-IPF, kunezinketho zokwelashwa ukuphatha izimpawu zakho nokuthuthukisa ikhwalithi yempilo yakho. Lokhu kufaka phakathi:

• izidakamizwa
• ukungenelela kwezokwelapha
• izinguquko endleleni yokuphila