Voriconazole

-Delile

• Izinkomba zeVoriconazole
• Intengo yeVoriconazole
• Imiphumela emibi ye-Voriconazole
• Ukuphikisana kweVoriconazole
• Ungayisebenzisa kanjani i-Voriconazole

IVoriconazole iyinto esebenzayo emuthini wokubulala owaziwa ngokuthengisa njengeVfend.

Le mithi yokusetshenziswa komlomo iyajova futhi ikhonjiswe ekwelapheni i-aspergillosis, ngoba isenzo sayo siphazamisa i-ergosterol, into ebalulekile yokugcina ubuqotho be-membrane yesikhunta sefungus, egcina ibuthaka futhi isuswe emzimbeni.

Izinkomba zeVoriconazole

I-Aspergillosis; ukutheleleka okunzima kwefungal.

Intengo yeVoriconazole

I-200 mg bunch yeVoriconazole equkethe i-ampoule ibiza cishe i-1,200 reais, ibhokisi lokusebenzisa ngomlomo elingu-200 mg eliqukethe amaphilisi ayi-14 libiza cishe i-5,000 reais.

Imiphumela emibi ye-Voriconazole

I-creatinine eyandisiwe; ukuphazanyiswa okubukwayo (ukuguqulwa noma ukwanda kokubona okubonakalayo; ukubona okungaboni kahle, ukuguqulwa kwemibala yokubona; ukuzwela ekukhanyeni)

Ukuphikisana kweVoriconazole

Ingozi Yokukhulelwa D; abesifazane abancelayo; hypersensitivity kumkhiqizo noma amanye ama-azoles; ukungabekezelelani kwe-galactose; ukushoda kwe-lactase.

Ungayisebenzisa kanjani i-Voriconazole

Ukusetshenziswa ngomjovo

Ukufakwa ngaphakathi.

Abantu abadala

• Umthamo wokuhlasela: 6 mg ngekhilogremu yesisindo somzimba njalo emahoreni ayi-12 ngemithamo emi-2, kulandelwa isilinganiso sokulondolozwa esingu-4 mg ngekhilogremu yesisindo somzimba njalo emahoreni ayi-12. Ngokushesha ngangokunokwenzeka (inqobo nje uma isiguli sikubekezelela), shintshela kumlomo. Uma isiguli singakubekezeleli, wehlisela ku-3 mg ngekhilogremu ngayinye yesisindo somzimba njalo ngo-12 h.
• Abadala: umthamo ofanayo nowabantu abadala.
• Iziguli ezinokwehluleka kwesibindi okulingene ukuya kokulingene: usike umthamo wesondlo phakathi.
• Iziguli ezinesibindi sokuqina kwesibindi: sebenzisa kuphela uma izinzuzo zidlula izingozi.
• Izingane ezineminyaka engama-12 ubudala: ukuphepha nokusebenza kahle akusungulwanga.

Ukusetshenziswa ngomlomo

Abantu abadala

• Isisindo esingaphezu kwama-40 kg: Umthamo wesondlo ungama-200 mg njalo emahoreni ayi-12, uma impendulo inganele, umthamo ungakhushulwa ufike ku-300 mg njalo emahoreni ayi-12 (uma isiguli singakubekezeleli, yenza izengezo ezingama-50 mg njalo emahoreni ayi-12).
• Isisindo esingaphansi kuka-40 kg: Umthamo wesondlo ka-100 mg njalo emahoreni ayi-12, uma impendulo inganele, umthamo ungakhushulwa ube ngu-150 mg njalo emahoreni ayi-12 (uma isiguli singakubekezeleli, sehlisele ku-100 mg njalo emahoreni ayi-12).
• Iziguli ezinokwehluleka kwesibindi: ukunciphisa umthamo kungadingeka.
• Abadala: imithamo efanayo neyabantu abadala.
• Izingane ezineminyaka engama-12 ubudala: ukuphepha nokusebenza kahle akusungulwanga.