I-sella syndrome engenalutho

Isifo se-sella esingenalutho yisimo lapho indlala yepituitary incipha noma isicabalele.

I-pituitary yindlala encane etholakala ngaphansi nje kobuchopho. Inamathele ezansi kobuchopho ngesiqu sepituitary. I-pituitary ihlala egunjini elifana nesihlalo ogebhezini oluthiwa yi-sella turcica. NgesiLatin, kusho isihlalo saseTurkey.

Lapho indlala yepituitary incipha noma icabalele, ayikwazi ukubonwa kuskena se-MRI. Lokhu kwenza indawo yendlala yebhinqa ibukeke njenge "sella engenalutho." Kepha i-sella empeleni ayinalutho. Kuvame ukugcwala i-cerebrospinal fluid (CSF). I-CSF inguketshezi oluzungeze ubuchopho nomgogodla. Nge-sella syndrome engenalutho, i-CSF ingene kwi-sella turcica, ifaka ingcindezi ku-pituitary. Lokhu kubangela ukuthi indlala inciphise noma ithambe.

I-sella syndrome engenalutho eyinhloko yenzeka lapho enye yezingqimba (i-arachnoid) emboza ingaphandle lobuchopho iqhubekela phansi ku-sella bese icindezela i-pituitary.

I-sella syndrome engenalutho yesibili yenzeka lapho i-sella ingenalutho ngoba indlala yesikhumba ilinyazwe yi:

• Isigaxa
• Ukwelashwa ngemisebe
• Ukuhlinzwa
• Ukuhlukumezeka

I-sella syndrome engenalutho ingabonakala esimweni esibizwa nge-pseudotumor cerebri, esithinta kakhulu abesifazane abasebasha, abakhuluphele futhi esidale ukuthi i-CSF ibe ngaphansi kwengcindezi ephezulu.

Indlala ye-pituitary yenza ama-hormone amaningi alawula ezinye izindlala emzimbeni, kufaka phakathi:

• Izindlala ze-adrenal
• Amaqanda
• Amasende
• Indlala yegilo

Inkinga ngendlala ye-pituitary ingaholela ezinkingeni nganoma yiziphi kulezi zindlala ezingenhla kanye namazinga ama-hormone angajwayelekile alezi zindlala.

Imvamisa, azikho izimpawu noma ukulahleka komsebenzi we-pituitary.

Uma kunezimpawu, zingafaka noma yikuphi okulandelayo:

• Izinkinga zokwakhiwa
• Ukuphathwa ikhanda
• Ukuya esikhathini okungajwayelekile noma okungekho
• Ukunciphisa noma ukungabi nesifiso sobulili (i-libido ephansi)
• Ukukhathala, amandla aphansi
• Ukukhishwa kwengono

I-sella syndrome eyize engenalutho ivame ukutholakala ngesikhathi sokuhlolwa kwekhanda nobuchopho nge-MRI noma i-CT. Umsebenzi wepituitary uvame ukujwayelekile.

Umhlinzeki wezokunakekelwa kwempilo anga-oda ukuhlolwa ukuze aqiniseke ukuthi indlala yepituitary isebenza ngokujwayelekile.

Kwesinye isikhathi, ukuhlolwa kwengcindezi ephezulu ebuchosheni kuzokwenziwa, njenge:

• Ukuhlolwa kwe-retina ngudokotela wezifo zamehlo
• Ukubhoboza i-Lumbar (umpompi womgogodla)

Kwi-sella syndrome eyinhloko engenalutho:

• Akukho ukwelashwa uma umsebenzi we-pituitary ujwayelekile.
• Imithi ingabelwa ukuthi yelaphe noma yimaphi amazinga ama-hormone angajwayelekile.

Kwi-sella syndrome yesibili engenalutho, ukwelashwa kubandakanya ukufaka esikhundleni sama-hormone angekho.

Kwezinye izimo, kudingeka ukuhlinzwa ukuze kulungiswe i-sella turcica.

I-sella syndrome engenalutho eyinhloko ayibangeli izinkinga zempilo, futhi ayithinti isikhathi sokuphila.

Izinkinga zesifo se-sella syndrome esingenalutho zibandakanya izinga eliphakeme kancane kunejwayelekile leprolactin. Le yihomoni eyenziwe yindlala ye-pituitary. Iprolactin ivuselela ukukhula kwamabele nokukhiqizwa kobisi kwabesifazane.

Izinkinga ze-sella syndrome yesibili engenalutho zihlobene nembangela yesifo se-pituitary gland noma yimiphumela ye-hormone encane kakhulu ye-pituitary (hypopituitarism).

Xhumana nomhlinzeki wakho uma uba nezimpawu zomsebenzi wepituitary ongajwayelekile, njengezinkinga zokuya esikhathini noma ukungabi namandla.

I-pituitary - i-sella syndrome engenalutho; I-sella engenalutho engaphelele

• Indlala yamapayipi

UKaiser U, Ho KKY. I-pituitary physiology kanye nokuhlolwa kokuxilongwa. Ku: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 13. IPhiladelphia, PA: Elsevier; 2016: isahluko 8.

UMaya M, uPeterman BD. Ukucabanga nge-pituitary. Ku: Melmed S, ed. I-Pituitary. Umhla wesi-4. IPhiladelphia, PA: Elsevier; I-2017: isahluko 23.

Molitch ME. I-pituitary yangaphakathi. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 224.