I-Neurosyphilis

I-Neurosyphilis igciwane lesandulela ngculaza noma umgogodla. Imvamisa kwenzeka kubantu asebenesifo sogcunsula esingalashwa iminyaka eminingi.

I-Neurosyphilis ibangelwa I-Treponema pallidum. Lona amagciwane abangela ugcunsula. I-Neurosyphilis ivame ukwenzeka cishe eminyakeni eyi-10 kuye kwengu-20 ngemuva kokuba umuntu etheleleke ngogcunsula okokuqala. Akuwona wonke umuntu onegcunsula eba nale nkinga.

Kunezinhlobo ezine ezihlukene ze-neurosyphilis:

• Asymptomatic (ifomu elivame kakhulu)
• I-paresis ejwayelekile
• I-Meningovascular
• Amathebhu dorsalis

I-neurosyphilis ye-Asymptomatic yenzeka ngaphambi kukagcunsula olubonakalayo. I-Asymptomatic isho ukuthi azikho izimpawu.

Izimpawu zivame ukuthinta uhlelo lwezinzwa. Ngokuya ngesimo se-neurosyphilis, izimpawu zingafaka noma yikuphi okulandelayo:

• Ukuhamba okungajwayelekile (gait), noma ukungakwazi ukuhamba
• Ukuba ndikindiki ezinzwaneni, ezinyaweni, noma emilenzeni
• Izinkinga ngokucabanga, njengokudideka noma ukugxila okungafanele
• Izinkinga zengqondo, njengokucindezeleka noma ukucasuka
• Ukuphathwa ikhanda, ukuqubuka, noma intamo elukhuni
• Ukulahlekelwa ukulawula isinye (incontinence)
• Ukuthuthumela, noma ubuthakathaka
• Izinkinga ezibonakalayo, ngisho nokungaboni

Umhlinzeki wakho wezokunakekelwa kwempilo uzokuhlola ngokomzimba futhi angathola okulandelayo:

• Izimo ezingejwayelekile
• Ukuncipha kwemisipha
• Ukuncipha kwemisipha
• Izinguquko zengqondo

Ukuhlolwa kwegazi kungenziwa ukuthola izinto ezikhiqizwa amagciwane abangela ugcunsula, lokhu kufaka:

• I-Treponema pallidum i-particle agglutination assay (TPPA)
• Isivivinyo se-Venereal research laboratory (VDRL)
• Ukufakwa kwe-fluorescent treponemal antibody (FTA-ABS)
• I-plasma reagin esheshayo (RPR)

Nge-neurosyphilis, kubalulekile ukuhlola uketshezi lomgogodla ukuthola izimpawu zogcunsula.

Ukuhlolwa kokubheka izinkinga ngohlelo lwezinzwa kungafaka:

• I-angiogram yobuchopho
• Iskena sekhanda le-CT
• Ukubhoboza i-Lumbar (umpompi womgogodla) kanye nokuhlaziywa kwe-cerebrospinal fluid (CSF)
• Ukuskena kwe-MRI kobuchopho, ubuchopho, noma umgogodla

I-penicillin elwa namagciwane isetshenziselwa ukwelapha i-neurosyphilis. Inganikezwa ngezindlela ezahlukahlukene:

• Ukujova emthanjeni izikhathi eziningana ngosuku izinsuku eziyi-10 kuya kwezingu-14.
• Ngomlomo amahlandla ama-4 ngosuku, kuhlanganiswe nemijovo yemisipha yansuku zonke, yomibili ethathwe izinsuku eziyi-10 kuye kwezingu-14.

Kufanele uhlolwe ngokulandela igazi ezinyangeni ezi-3, 6, 12, 24, nezingama-36 ukuqinisekisa ukuthi ukutheleleka sekuphelile. Uzodinga ama-lumbar punctures wokulandelela wokuhlaziywa kwe-CSF njalo ezinyangeni eziyisithupha. Uma une-HIV / AIDS noma esinye isimo sempilo, uhlelo lwakho lokulandelela lungahluka.

I-Neurosyphilis iyinkinga esongela impilo yogcunsula. Ukwenza kahle kangakanani kuya ngokuthi i-neurosyphilis inzima kangakanani ngaphambi kokwelashwa. Inhloso yokwelashwa ukuvimbela ukuwohloka okuqhubekayo. Eziningi zalezi zinguquko azibuyiseki.

Izimpawu zingakhula kancane kancane.

Shayela umhlinzeki wakho uma uke waba nogcunsula esikhathini esedlule futhi manje unezimpawu zezinkinga zesistimu yezinzwa.

Ukuxilongwa nokwelashwa kwesifo sogcunsula sokuqala kungavimbela i-neurosyphilis.

Ugcunsula - i-neurosyphilis

• Isistimu yezinzwa emaphakathi nesistimu yezinzwa ezungezayo
• Ugcunsula osezingeni eliphezulu

U-Euerle BD. Ukubhoboza umgogodla nokuhlolwa koketshezi lwe-cerebrospinal. Ku: Roberts JR, Custalow CB, Thomsen TW, ama-eds. Izinqubo Zomtholampilo zikaRoberts noHedges ku-Emergency Medicine kanye ne-Acute Care. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2019: isahluko 60.

I-National Institute of Neurological Disorders and Stroke iwebhusayithi. I-Neurosyphilis. www.ninds.nih.gov/Disorders/All-Disorders/Neurosyphilis-Information-Page. Kubuyekezwe ngoMashi 27, 2019. Kufinyelelwe ngoFebhuwari 19, 2021.

URadolf JD, iTramont EC, uSalazar JC. Ugcunsula (Treponema pallidum). Ku: Bennett JE, Dolin R, Blaser MJ, ama-eds. Mandell, Douglas, kanye neBennett's Principles and Practice of Infectious Diseases. Umhlaka 9. IPhiladelphia, PA: Elsevier; 2020: isahluko 237.