Ukuhlolwa kwama-Coombs

Ukuhlolwa kweCoombs kubheka amasosha omzimba angahle anamathele kumaseli akho abomvu egazi futhi abangele ukuthi amangqamuzana abomvu egazi asheshe afe.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile okudingekile kulolu vivinyo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

Kunezinhlobo ezimbili zokuhlolwa kweCoombs:

• Ngqo
• Okungaqondile

Ukuhlolwa okuqondile kweCoombs kusetshenziselwa ukuthola amasosha omzimba anamathele ebusweni bamaseli abomvu egazi. Izifo eziningi nezidakamizwa kungadala ukuthi lokhu kwenzeke. La ma-antibodies kwesinye isikhathi abulala amangqamuzana abomvu egazi futhi abangele i-anemia. Umhlinzeki wakho wokunakekelwa kwezempilo angancoma lokhu kuhlolwa uma unezimpawu noma izimpawu ze-anemia noma i-jaundice (ukuphuzi kwesikhumba noma kwamehlo).

Ukuhlolwa okungaqondile kweCoombs kubheka amasosha omzimba antanta egazini. La ma-antibodies angenza ngokumelene namaseli athile abomvu egazi. Lokhu kuhlolwa kuvame ukwenziwa ukuthola ukuthi ungaphendula yini ekufakelweni igazi.

Umphumela ojwayelekile ubizwa ngomphumela ongemuhle. Kusho ukuthi bekungekho ukuhlangana kwamaseli futhi awunawo amasosha omzimba kumaseli abomvu egazi.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Ukuhlolwa okungajwayelekile (okuhle) okuqondile kwe-Coombs kusho ukuthi unamasosha omzimba aphikisana namaseli akho abomvu egazi. Lokhu kungabangelwa:

• I-autoimmune hemolytic anemia
• I-lymphocytic leukemia noma isifo esifanayo
• Isifo segazi ezinganeni ezisanda kuzalwa esibizwa nge-erythroblastosis fetalis (esibizwa nangokuthi isifo se-hemolytic sosana olusanda kuzalwa)
• I-mononucleosis ethathelwanayo
• Ukutheleleka kwe-Mycoplasma
• Ugcunsula
• Uhlelo lupus erythematosus
• Ukusabela kokumpontshelwa, njengaleyo ngenxa yamayunithi wegazi afaniswe ngokungafanele

Umphumela wokuhlolwa ungahle ube ongajwayelekile ngaphandle kwesizathu esicacile, ikakhulukazi kubantu abadala.

Ukuhlolwa okungajwayelekile (okuhle) okungaqondile kweCoombs kusho ukuthi unamasosha omzimba azosebenza ngokumelene namaseli abomvu egazi umzimba wakho awubheka njengowangaphandle. Lokhu kungaphakamisa:

• I-Erythroblastosis fetalis
• Umdlalo wegazi ongahambelani (uma usetshenziswa emabhange egazi)

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukopha ngokweqile
  
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Ukuhlolwa okuqondile kwe-antiglobulin; Ukuhlolwa okungaqondile kwe-antiglobulin; I-anemia - i-hemolytic

I-Elghetany MT, iSchexneider KI, ukuphazamiseka kwe-Banki K. Erythrocytic. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 32.

UMichel M. Autoimmune kanye ne-intravascular hemolytic anemias. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 151.