Isici se-rheumatoid (RF)

I-rheumatoid factor (RF) ukuhlolwa kwegazi okukala inani le-antibody ye-RF egazini.

Isikhathi esiningi, igazi likhishwa emthanjeni ongaphakathi endololwaneni noma ngemuva kwesandla.

Ezinsaneni noma ezinganeni ezincane, ithuluzi elibukhali elibizwa ngokuthi i-lancet lingasetshenziselwa ukubhoboza isikhumba.

• Igazi liqoqa kuthubhu encane yengilazi ebizwa nge-pipette, noma kwi-slide noma kumugqa wokuhlola.
• Kubekwa ibhandishi phezu kwale ndawo ukunqanda ukuphuma kwegazi.

Isikhathi esiningi, awudingi ukuthatha izinyathelo ezikhethekile ngaphambi kwalolu vivinyo.

Ungase uzwe ubuhlungu obuncane noma isitinyela lapho kufakwa inaliti. Ungase futhi uzizwe ushaywa yisiza ngemuva kokukhishwa kwegazi.

Lokhu kuhlolwa kuvame ukusetshenziselwa ukusiza ukuxilonga isifo samathambo noma isifo se-Sjögren.

Imiphumela ivame ukubikwa ngenye yezindlela ezimbili:

• Inani, elejwayelekile lingaphansi kuka-15 IU / mL
• Ithenda, ejwayelekile ngaphansi kuka-1: 80 (1 kuya ku-80)

Uma umphumela ungaphezu kwezinga elijwayelekile, ulungile. Inombolo ephansi (imiphumela emibi) imvamisa isho ukuthi awunaso isifo samathambo noma iSjögren syndrome. Kodwa-ke, abanye abantu abanale mibandela basene-RF engeyinhle noma ephansi.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Umphumela ongajwayelekile usho ukuthi ukuhlolwa kutholakele, okusho ukuthi izinga eliphakeme le-RF litholakele egazini lakho.

• Iningi labantu abane-arthritis ye-rheumatoid noma i-Sjögren syndrome banezivivinyo ezinhle ze-RF.
• Izinga eliphakeme, kungenzeka ukuthi eyodwa yalezi zimo ikhona. Kukhona nezinye izivivinyo zalezizinkinga ezisiza ukwenza ukuxilongwa.
• Akuwona wonke umuntu onezinga eliphakeme le-RF one-rheumatoid arthritis noma i-Sjögren syndrome.

Umhlinzeki wakho kufanele futhi enze olunye uvivinyo lwegazi (anti-CCP antibody), ukusiza ukuxilonga isifo samathambo (RA). I-anti-CCP antibody icacise kakhulu i-RA kune-RF. Ukuhlolwa okuyi-antibody ye-CCP kusho ukuthi i-RA mhlawumbe ukuxilongwa okulungile.

Abantu abanezifo ezilandelayo bangaba namazinga aphezulu e-RF:

• I-Hepatitis C
• Uhlelo lupus erythematosus
• I-dermatomyositis ne-polymyositis
• I-Sarcoidosis
• I-cryoglobulinemia exubile
• Isifo esixubile sezicubu

Amazinga aphezulu kunejwayelekile we-RF angabonakala kubantu abanezinye izinkinga zezokwelapha. Kodwa-ke, lawa mazinga aphezulu e-RF awakwazi ukusetshenziselwa ukuxilonga lezi ezinye izimo:

• Ingculaza, isifo sokusha kwesibindi, umkhuhlane, i-mononucleosis esithathelwanayo, nezinye izifo ezibangelwa amagciwane
• Izifo ezithile zezinso
• I-Endocarditis, isifo sofuba nezinye izifo ezibangelwa amagciwane
• Ukutheleleka ngama-parasite
• I-leukemia, i-myeloma eminingi, neminye imidlavuza
• Isifo samaphaphu esingapheli
• Isifo esingalapheki sesibindi

Kwezinye izimo, abantu abaphilile futhi abanayo enye inkinga yezokwelapha bazoba nezinga eliphezulu le-RF elijwayelekile.

• Ukuhlolwa kwegazi

U-Aletaha D, uNeogi T, uSilman AJ, et al. Izindlela zokuhlukanisa i-Rheumatoid arthritis 2010: i-American College of Rheumatology / European League Against Rheumatism isinyathelo sokubambisana. U-Ann Rheum Dis. 2010; 69 (9): 1580-1588. I-PMID: 20699241 www.ncbi.nlm.nih.gov/pubmed/20699241.

U-Andrade F, uDarrah E, uRosen A. Ama-Autoantibodies ku-arthritis ye-rheumatoid. Ku: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, abahleli. Incwadi kaKelley noFirestein yeRheumatology. Umhlaka 10. IPhiladelphia, PA: Elsevier; 2017: isahluko 56.

UHoffmann MH, Trouw LA, uSteiner G. Autoantibodies ku-rheumatoid arthritis. Ku: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, abahleli. I-Rheumatology. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2019: isahluko 99.

UMason JC. Izifo ze-rheumatic kanye nesistimu yenhliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann, DL, Tomaselli GF, Braunwald E, ama-eds. Isifo Senhliziyo SikaBraunwald: Incwadi Yemithi Yezinhliziyo Nemithambo. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2019: isahluko 94.

I-Pisetsky DS. Ukuhlolwa kwelabhoratri ezifweni zamathambo. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 257.

von Mühlen CA, Fritzler MJ, Chan EKL. Ukuhlolwa kwemitholampilo kanye nelabhorethri yezifo ze-rheumatic system. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 52.