Ukuhlolwa kwegazi le-Parathyroid (PTH)

Ukuhlolwa kwe-PTH kukala izinga le-hormone ye-parathyroid egazini.

I-PTH imele i-hormone ye-parathyroid. I-hormone yamaprotheni ekhishwe yindlala ye-parathyroid.

Ukuhlolwa kwelabhorethri kungenziwa ukukala inani le-PTH egazini lakho.

Kudingeka isampula yegazi.

Buza umhlinzeki wakho wezempilo ukuthi kufanele uyeke ukudla noma ukuphuza isikhathi esithile ngaphambi kokuhlolwa. Imvamisa, awudingi ukuzila ukudla noma ukuyeka ukuphuza.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

I-PTH ikhishwa yizindlala ze-parathyroid. Izindlala ze-4 ezincane ze-parathyroid zitholakala entanyeni, eduze noma ezinamathiselwe ohlangothini olungemuva lwendlala yegilo. Indlala yegilo ikhona entanyeni, ngenhla nje lapho kuhlangana khona amathambo akho ophakathi nendawo.

I-PTH ilawula amazinga e-calcium, i-phosphorus, ne-vitamin D egazini. Kubalulekile ukulawula ukukhula kwamathambo. Umhlinzeki wakho anga-oda lokhu kuhlolwa uma:

• Unezinga eliphakeme le-calcium noma eliphansi le-phosphorus egazini lakho.
• Une-osteoporosis ebucayi engachazeki noma engaphenduli ekwelashweni.
• Unesifo sezinso.

Ukusiza ukuqonda ukuthi i-PTH yakho ijwayelekile, umhlinzeki wakho uzokala i-calcium yakho yegazi ngasikhathi sinye.

Amanani ajwayelekile angama-picograms ayi-10 kuya kwangama-55 ngemililitha (pg / mL).

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye izinhlobo ezihlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Inani le-PTH ebangeni elijwayelekile lisengafaneleka lapho amazinga e-serum calcium ephezulu. Khuluma nomhlinzeki wakho mayelana nokuthi umphumela wakho usho ukuthini.

Izinga eliphakeme kunokujwayelekile lingavela nge:

• Ukuphazamiseka okwandisa amazinga e-phosphate noma e-phosphorus egazini, njengesifo sezinso sesikhathi eside (esingapheli)
• Ukwehluleka komzimba ukuphendula ku-PTH (pseudohypoparathyroidism)
• Ukuntuleka kwe-calcium, okungabangelwa ukungayidli i-calcium eyanele, ukungamunci i-calcium esiswini, noma ukulahlekelwa i-calcium eningi emchameni wakho
• Ukukhulelwa noma ukuncelisa ibele (akuvamile)
• Ukuvuvukala kwezindlala ze-parathyroid, ezibizwa nge-primary hyperparathyroidism
• Amathumba endlala ye-parathyroid, ebizwa nge-adenomas
• Ukuphazamiseka kuka-Vitamin D, kufaka phakathi ukukhanya kwelanga okwanele kubantu abadala asebekhulile nezinkinga zokumunca, ukwehla nokusebenzisa uvithamini D emzimbeni

Izinga eliphansi kunokujwayelekile lingavela nge:

• Ukususwa ngengozi kwezindlala ze-parathyroid ngesikhathi sokuhlinzwa kwe-thyroid
• Ukubhujiswa okuzenzakalelayo kwendlala ye-parathyroid
• Umdlavuza oqala kwenye ingxenye yomzimba (njengesifuba, amaphaphu, noma ikholoni) bese usabalalela ethanjeni
• I-calcium eyeqile esikhathini eside imvamisa ivela kuma-calcium amaningi noma ama-antacids athile, aqukethe i-calcium carbonate noma i-sodium bicarbonate (i-baking soda)
• Izindlala zeParathyroid azikhiqizi i-PTH eyanele (hypoparathyroidism)
• Amazinga aphansi we-magnesium egazini
• Kushisa bhé kule ndawo ngezindlala ze-parathyroid
• I-Sarcoidosis nesifo sofuba
• Ukudla okweqile kukavithamini D

Eminye imibandela ukuhlolwa okunga-odwa kuyo ifaka:

• Ama-endocrine neoplasia amaningi (AMADODA) I
• Ama-endocrine neoplasia amaningi (AMADODA) II

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukubhoboza okuningi ukuthola imithambo
• Ukuquleka noma uzizwe unekhanda elincane
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-Parathormone; I-Parathormone (PTH) i-molecule engaguquki; I-PTH ehambisanayo; Hyperparathyroidism - Ukuhlolwa kwegazi kwe-PTH; I-Hypoparathyroidism - Ukuhlolwa kwegazi kwe-PTH

I-Bringhurst FR, iDemay MB, iKronenberg HM. AmaHormoni nokuphazamiseka kwesimo semaminerali. Ku: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 13. IPhiladelphia, PA: Elsevier; 2016: isahluko 28.

UKlemm KM, uKlein MJ. Omaka bezinto eziphilayo zamathambo metabolism. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. IPhiladelphia, PA: Elsevier; I-2017: isahluko 15.