U-Erlotinib

-Delile

• Ngaphambi kokuthatha i-erlotinib,
• I-Erlotinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Erlotinib isetshenziselwa ukwelapha izinhlobo ezithile zomdlavuza wamaphaphu weseli ongasencane osabalalele ezicutshini eziseduze noma kwezinye izingxenye zomzimba ezigulini esezelashwe okungenani ngomuthi owodwa we-chemotherapy futhi ezingakabi ngcono. I-Erlotinib isetshenziswa futhi ngokuhlangana nomunye umuthi (i-gemcitabine [Gemzar]) ukwelapha umdlavuza wepancreatic osabalalele ezicutshini eziseduze noma kwezinye izingxenye zomzimba futhi ongakwazi ukwelashwa ngokuhlinzwa. U-Erlotinib usesigabeni semithi ebizwa nge-kinase inhibitors. Isebenza ngokuvimba isenzo sephrotheni engavamile ekhombisa ukuthi amangqamuzana omdlavuza ayanda. Lokhu kusiza ukunciphisa noma ukumisa ukusabalala kwamangqamuzana omdlavuza.

U-Erlotinib uza njengethebhulethi azoyithatha ngomlomo. Imvamisa ithathwa esiswini esingenalutho kanye ngosuku, okungenani ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla isidlo noma isidlo. Thatha i-erlotinib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-erlotinib njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho anganciphisa umthamo wakho we-erlotinib ngesikhathi sokwelashwa kwakho. Lokhu kuncike ekutheni umuthi usebenza kanjani kuwe kanye nemiphumela emibi oyitholayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho. Qhubeka uthathe i-erlotinib noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-erlotinib ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-erlotinib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-erlotinib, noma imuphi omunye umuthi, noma iziphi izithako ezibhebheni ze-erlotinib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela noma engabhaliswanga, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: i-angiogenesis inhibitors efana ne-bevacizumab (Avastin); ama-anticoagulants (’ama-thinner egazi’) afana ne-warfarin (Coumadin); ama-antifungal anjenge-itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), ne-voriconazole (Vfend); i-boceprevir (i-Victrelis); carbamazepine (Tegretol); i-ciprofloxacin (Cipro, Proquin XR); i-clarithromycin (i-Biaxin); i-conivaptan (iVaprisol); I-HIV protease inhibitors efana ne-atazanavir (Reyataz), indinavir (Crixivan), lopinavir / ritonavir (Kaletra), nelfinavir (Viracept), ritonavir (Norvir), ne-saquinavir (Fortovase, Invirase); H₂ ama-blocker afana ne-cimetidine (Tagamet), i-famotidine (i-Pepcid), i-nizatidine (i-Axid), ne-ranitidine (i-Zantac); imithi yezinduna efana ne-benzoyl peroxide (e-Epiduo, eBenzaClin, eBenzamycin, abanye); i-midazolam (iVesi): nefazodone; izidakamizwa ezingezona ukuvuvukala (ama-NSAID) ezinjenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-steroids yomlomo efana ne-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (i-Medrol), ne-prednisone (i-Deltasone); i-phenobarbital (Luminal, Solfoton); i-phenytoin (iDilantin); ama-proton pump inhibitors afana ne-esomeprazole (Nexium), i-lansoprazole (i-Prevacid), i-omeprazole (i-Prilosec), i-pantoprazole (i-Protonix), ne-rabeprazole (i-AcipHex); i-rifabutin (i-Mycobutin); i-rifampin (i-Rifadin, i-Rimactane); i-rifapentine; imithi yetekisi yomdlavuza efana ne-docetaxel (Taxotere) ne-paclitaxel (Abraxane, Taxol); i-telithromycin (Ketek); teriflunomide (Aubagio); ne-troleandomycin (TAO) (ayitholakali e-U.S.). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-erlotinib, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• uma uthatha ama-antacids, thatha amahora ambalwa ngaphambi noma amahora ambalwa ngemuva kokuthatha i-erlotinib.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• Tshela udokotela wakho uma welashwa noma usanda kwelashwa ngamakhemikhali noma ngemisebe (ukwelashwa komdlavuza osebenzisa amagagasi ezinhlayiya zamandla aphezulu ukubulala amangqamuzana omdlavuza). Phinda utshele udokotela wakho uma uke waba nesifo samaphaphu noma ukutheleleka, izilonda zesisu, izifo eziguquguqukayo (isimo lapho kwakhiwa khona amaphakethe angavamile emathunjini amakhulu futhi angavuvuka), noma isifo sesibindi noma sezinso.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Akufanele ukhulelwe ngenkathi uthatha i-erlotinib futhi okungenani inyanga engu-1 ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ongazisebenzisa. Uma ukhulelwa, shayela udokotela wakho ngokushesha. U-Erlotinib angalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ngesikhathi sokwelashwa kwakho nge-erlotinib futhi kuze kube amasonto ama-2 ngemuva komthamo wakho wokugcina.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-erlotinib.
• utshele udokotela wakho uma usebenzisa imikhiqizo kagwayi. Ukubhema ugwayi kunganciphisa ukusebenza kwalo muthi.
• hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside nokugqoka isigqoko, ezinye izingubo zokuzivikela, izibuko zelanga, kanye nelanga. Khetha i-sunscreen enesici sokuvikela ilanga (SPF) okungenani esingu-15 futhi iqukethe i-zinc oxide noma i-titanium dioxide. Ukuvezwa yilanga kwandisa ubungozi bokuthi uzoba nokuqubuka ngesikhathi sokwelashwa kwakho ne-erlotinib.
• kufanele wazi ukuthi i-erlotinib ingadala ukuqubuka nezinye izinkinga zesikhumba. Ukuze uvikele isikhumba sakho, sebenzisa umswakama ongenatshwala omncane, ugeze isikhumba sakho ngensipho emnene, bese ususa izimonyo ngomuthi ohlanza kancane.

Gwema ukudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi usebenzisa lo muthi.

Ukuvimbela isifo sohudo esingabangelwa yi-erlotinib, phuza ama-sips amancane ketshezi njengesiphuzo sezemidlalo esingenashukela kaningi usuku lonke, udle ukudla okuncane okunjengama-crackers kanye ne-toast, futhi ugweme ukudla okubabayo.

Thatha umthamo olandelayo ngesikhathi sakho esivamile ngosuku olulandelayo. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Erlotinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukulahlekelwa isifiso sokudla
• isicanucanu
• ukuhlanza
• isilungulela
• igesi
• ukuqunjelwa
• izilonda zomlomo
• ukuncipha komzimba
• ukukhathala ngokweqile
• ikhanda
• ubuhlungu bamathambo noma imisipha
• ukudana
• ukukhathazeka
• ukuba ndikindiki, ukushiswa, noma ukushaywa izandla noma izinyawo
• ukuvuvukala kwezingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi
• ukufiphala kwesikhumba
• ukulahleka kwezinwele
• izinguquko ekubukeni kwezinwele nezinzipho

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka (kungabukeka njengezinduna futhi kungathinta isikhumba ebusweni, esifubeni esingenhla, noma emuva)
• ukushwabana, ukuxebuka, ukoma noma ukuqhekeka kwesikhumba
• ukulunywa, ubumnene, noma ukushiswa kwesikhumba
• ukuphelelwa umoya
• ukukhwehlela
• umkhuhlane noma amakhaza
• ukukhula kwezinkophe ngaphakathi kwejwabu leso
• ubuhlungu obukhulu besisu
• amehlo omile, abomvu, abuhlungu, ahlengekayo, noma acasukile
• ukungaboni kahle
• ukuzwela kweso ekukhanyeni
• ubuhlungu besifuba noma ingcindezi
• ubuhlungu ezingalweni, entanyeni, noma eqolo
• ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla
• inkulumo ehamba kancane noma enzima
• isiyezi noma ukuquleka
• ubuthakathaka noma ukuba ndikindiki kwengalo noma komlenze
• ukulimaza noma ukopha okungavamile
• ezimnyama nezilindayo noma ezinezihlalo ezinegazi
• uhlanza olunegazi noma olubukeka njengezizathu zekhofi
• amehlo acwile
• umlomo owomile
• ukuncipha kokuchama
• umchamo omnyama
• isikhumba esiphaphathekile noma esiphuzi
• ububomvu, imfudumalo, ubuhlungu, isisa, noma ukuvuvukala emlenzeni owodwa

I-Erlotinib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isifo sohudo
• ukuqubuka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-erlotinib.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UTarceva^®