Bexarotene

-Delile

• Ngaphambi kokuthatha i-bexarotene,
• I-Bexarotene ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

I-Bexarotene akumele ithathwe yiziguli ezikhulelwe noma ezingakhulelwa. Kunobungozi obukhulu bokuthi i-bexarotene izodala ukuthi ingane izalwe inokukhubazeka kokuzalwa (izinkinga ezikhona ngesikhathi sokuzalwa).

Khuluma nodokotela wakho ngezingozi zokuthatha i-bexarotene.

Ezigulini zesifazane:

Uma ungakhulelwa, kuzodingeka ugweme ukukhulelwa ngesikhathi sokwelashwa kwakho nge-bexarotene. Kufanele usebenzise izindlela ezimbili ezamukelekayo zokulawula ukubeletha inyanga eyodwa ngaphambi kokuba uqale ukuthatha i-bexarotene, ngaso sonke isikhathi ngesikhathi ukwelashwa kwakho, nangenyanga e-1 ngemuva kokwelashwa kwakho. Udokotela wakho uzokutshela ukuthi yiziphi izindlela zokulawula ukubeletha ezamukelekayo. I-Bexarotene inganciphisa ukusebenza kahle kwezindlela zokuvimbela inzalo ngamahomoni (amaphilisi okulawula ukubeletha, amabala, izindandatho, okufakelwa kanye nemijovo), ngakho-ke kubaluleke kakhulu ukusebenzisa indlela yesibili yokulawula inzalo kanye nalolu hlobo lokuvimbela inzalo.

Uzoqala ukuthatha i-bexarotene ngosuku lwesibili noma lwesithathu esikhathini sakho sokuya esikhathini. Kufanele ube nokuhlolwa kokukhulelwa okungekuhle kungakapheli isonto elilodwa uqale ukwelashwa kwakho futhi njalo ngenyanga ngenkathi welashwa. Ngemuva kokuhlolwa ngakunye kokukhulelwa okungalungile, uzonikezwa kuphela i-bexarotene yenyanga engu-1.

Yeka ukuthatha i-bexarotene bese ushayela udokotela wakho ngokushesha uma ucabanga ukuthi ukhulelwe, uphuthelwa ukuya esikhathini, noma uya ocansini ngaphandle kokusebenzisa izindlela ezimbili zokulawula ukubeletha.

Ezigulini zesilisa:

Kufanele usebenzise ikhondomu njalo uma uhlangana nowesifazane okhulelwe noma okwazi ukukhulelwa ngenkathi uthatha i-bexarotene kanye nenyanga e-1 ngemuva kokwelashwa kwakho. Shayela udokotela wakho uma umlingani wakho ekhulelwa ngalesi sikhathi.

I-Bexarotene isetshenziselwa ukwelapha i-T-cell lymphoma (CTCL, uhlobo lomdlavuza wesikhumba) kubantu abanesifo esingalapheki ngempumelelo okungenani ngomunye umuthi. UBexarotene usesigabeni semithi ebizwa ngama-retinoids. Isebenza ngokumisa ukukhula kwamangqamuzana omdlavuza.

UBexarotene uza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku ngokudla. Thatha i-bexarotene ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-bexarotene njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlafune ama-capsule noma uwaqede uketshezi noma emlonyeni wakho. Uma ungakwazi ukugwinya amaphilisi aphelele, khuluma nodokotela wakho.

I-Bexarotene ingaba yingozi uma ingena esikhunjeni. Ungawathinti ama-capsule noma i-powder kusuka kuma-capsules uma ephukile noma evuza. Uma i-powder evela ku-capsule ephukile ifika esikhunjeni sakho, geza indawo ngensipho namanzi ngokushesha bese ushayela udokotela wakho.

Udokotela wakho uzokuqala ngomthamo omaphakathi we-bexarotene futhi anganciphisa umthamo wakho uma uba nemiphumela engemihle noma wandise umthamo wakho uma isimo sakho singathuthuki.

Kungathatha izinyanga ezimbalwa noma ngaphezulu ngaphambi kokuthi uqaphele inzuzo ephelele ye-bexarotene. Ungayeki ukuthatha i-bexarotene ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-bexarotene,

• utshele udokotela wakho kanye nosokhemisi uma unegciwane ku-bexarotene; noma enye i-retinoid, efana ne-acitretin (Soriatane), etretinate (Tegison), isotretinoin (Accutane), noma i-tretinoin (Vesanoid); noma yimuphi omunye umuthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amiodarone (Cordarone); ezinye izinto zokuvikela ezifana ne-ketoconazole (i-Nizoral) ne-itraconazole (i-Sporanox); i-cimetidine (Tagamet); i-clarithromycin (i-Biaxin); i-diltiazem (iCardizem); i-erythromycin (E.E.S., E-Mycin, Erythrocin); i-fluvoxamine; i-gemfibrozil (i-Lopid), i-HIV protease inhibitors efana ne-indinavir (Crixivan), i-nelfinavir (i-Viracept), ne-ritonavir (i-Norvir, e-Kaletra); i-insulin nemithi yomlomo yesifo sikashukela; nefazodone; i-phenobarbital; i-phenytoin (iDilantin); i-rifampin (i-Rifadin, i-Rimactane); i-tamoxifen (i-Nolvadex); i-verapamil (Calan); novithamini A. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-bexarotene, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho uma uphuza noma wake waphuza utshwala obuningi. Phinda utshele udokotela wakho uma uke waba ne-pancreatitis noma wake waba nayo; amazinga aphezulu e-cholesterol nezinye izinto ezinamafutha egazini; isifo sikashukela; ngamehlo; noma inyongo, igilo, izinso, noma isifo sesibindi.
• tshela udokotela wakho uma uncelisa.
• buza udokotela wakho ngokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi uthatha i-bexarotene. Utshwala bungenza imiphumela emibi evela ku-bexarotene ibe yimbi kakhulu.
• hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside futhi ugqoke izingubo zokuzivikela, izibuko zelanga, nesikhumba selanga. I-Bexarotene ingenza isikhumba sakho sizwele ekukhanyeni kwelanga.

Khuluma nodokotela wakho ngokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Thatha umthamo ophuthelwe ngokudla ngokushesha nje lapho usakukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Bexarotene ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ubuthakathaka
• ukukhathala
• ukwanda kokuzwela emakhazeni
• ukwanda kwesisindo
• ukudana
• ubuhlungu obuhlangene noma besisipha
• izinwele ezondile, ezinamafinyila noma izinzipho
• ukuqunjelwa
• ukuqubuka
• isikhumba esomile
• ububomvu, ukukala, noma ukulunywa kwesikhumba
• ukulahleka kwezinwele
• ukuvuvukala kwamaqakala, izinyawo, nemilenze
• ubunzima bokulala noma ukulala
• isicanucanu
• ukuhlanza
• isifo sohudo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ubuhlungu bomhlane noma besisu obuzumayo noma obuqhubekayo
• isicanucanu esinzima futhi esiqhubekayo nokuhlanza
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• izinguquko embonweni

I-Bexarotene ingakhuphula amazinga e-cholesterol namanye amafutha egazini lakho futhi ingavimbela indlala yakho yegilo ukuthi isebenze ngokujwayelekile. Udokotela wakho uzokuqapha ngokucophelela ukuze abone ukuthi ngabe uhlangabezana yini neminye yale miphumela emibi. Uma uhlangabezana neminye yale miphumela emibi, udokotela wakho angakunikeza omunye umuthi wokulawula imiphumela emibi ngenkathi uthatha i-bexarotene.

I-Bexarotene ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Ukugcine ekamelweni lokushisa kude nokushisa okweqile, ukukhanya nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-bexarotene.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi uthatha i-bexarotene.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Targretin^® Amaphilisi