Umjovo weCaplacizumab-yhdp

-Delile

• Ngaphambi kokuthola i-caplacizumab-yhdp,
• ICaplacizumab-yhdp ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

Umjovo weCaplacizumab-yhdp usetshenziselwa ukwelapha ukutholwa kwe-thrombotic thrombocytopenic purpura (aTTP; ukuphazamiseka lapho umzimba uhlasela khona futhi udale amahlule, inani eliphansi lamaplatelets namaseli abomvu egazi, futhi kungadala ezinye izinkinga ezinkulu) kuhlanganiswe ne-plasma exchange therapy futhi imishanguzo yokuzivikela emzimbeni. ICaplacizumab-yhdp isekilasini lemithi ebizwa ngama-antithrombotic agents. Isebenza ngokuvimba ukusebenza kwento ethile emzimbeni edala izimpawu ze-TTP.

ICaplacizumab-yhdp iza njengempuphu ezoncibilika kuketshezi futhi inikezwe ngomjovo (emthanjeni) noma ngomjovo ongaphansi (ngaphansi kwesikhumba). Imvamisa inikezwa ngosuku lokuqala lokwelashwa njengomjovo we-intravenous okungenani imizuzu eyi-15 ngaphambi kokushintshaniswa kwe-plasma, bese kuthi futhi njengomjovo ongena ngaphansi ngemuva kokuqedwa kwe-plasma Ngemuva kosuku lokuqala lokwelashwa kuvame ukunikezwa njengomjovo owodwa osetshenziswa nsuku zonke ngokulandela ukushintshaniswa kwe-plasma inqobo nje uma uthola ukwelashwa kokushintshaniswa kweplasma, bese kuthi kanye ngosuku nsuku zonke izinsuku ezingama-30 kuya kwezingama-58 ngemuva kokuyeka ukwelashwa kokushintshaniswa kweplasma. Sebenzisa i-caplacizumab-yhdp ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-caplacizumab-yhdp njengoba kuqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angakuvumela noma umnakekeli enze imijovo ekhaya. Cela udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozokwenza imijovo ukuthi angayilungisa kanjani futhi ayijoje i-caplacizumab-yhdp. Ngaphambi kokusebenzisa umjovo we-caplacizumab-yhdp okokuqala ngqa, funda imiyalelo ebhaliwe eza nayo. Buza usokhemisi noma udokotela wakho ikhophi lemiyalo yomkhiqizi yolwazi lokusebenzisa isiguli.

Kufanele ujove umjovo we-caplacizumab-yhdp ngomgogodla endaweni yesisu (esiswini) kepha gwema inkaba yakho nendawo engamasentimitha ama-5 ukuyizungeza. Musa ukujova endaweni efanayo izinsuku ezimbili zilandelana.

Lahla izinaliti, imijovo, nezitsha ezisemgodini ongamelana nokubhoboza. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-caplacizumab-yhdp,

• Tshela udokotela kanye nosokhemisi wakho uma une-allergies ku-caplacizumab-yhdp, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-caplacizumab-yhdp. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: apixaban (Eliquis), clopidogrel (Plavix), dabigatran (Pradaxa), dipyrimadole (Persantine, in Aggrenox), edoxaban (Savaysa), enoxaparin (Lovenox), fondaparinux (Arixtra), heparin, prasugrel (I-Effient), i-rivaroxaban powder (i-Xarelto), i-ticagrelor (i-Brilinta), noma i-warfarin (i-Coumadin, i-Jantoven). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waba ne-hemophilia noma (wake waba nesifo sofuzo lapho umzimba ungakwazi ukumisa ukopha kahle) noma ezinye izinkinga zokopha, noma isifo sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola i-caplacizumab-yhdp, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-caplacizumab-yhdp. Udokotela wakho noma udokotela wamazinyo angakutshela ukuthi ungasebenzisi i-caplacizumab-yhdp izinsuku eziyi-7 ngaphambi kokuhlinzwa.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Sebenzisa umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma ungasayitholi imishanguzo yokushintshaniswa nge-plasma, futhi kudlule amahora angaphezu kwangu-12 selokhu umthamo ongabanjwanga, yeqa umthamo ongabanjwanga bese uqhubeka nesimiso sakho sokulinganisa ngezikhathi ezivamile. Ungasebenzisi umthamo ophindwe kabili ukwenza okulahlekile.

ICaplacizumab-yhdp ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ukukhathala ngokweqile
• ukuhlungu obusemhlane
• ubuhlungu bemisipha
• ukuhayiza, ukubhoboza, noma ukuzwa isikhumba esikhunjeni
• ukulunywa eduze kwalapho umuthi wajova khona
• ukuphelelwa umoya
• imfiva

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isifuba
• ukopha okunzima okungayeki ukufaka ukopha okuvela engxenyeni, isitho sangasese sangasese, ikhala, izinsini noma indawo lapho kwajova khona umuthi
• ukuhlanza igazi
• izitulo zokubambezela ezibomvu, noma ezimnyama
• igazi emchameni
• ikhanda elibuhlungu ngokuzumayo, isicanucanu, ukuhlanza
• ngokuzumayo, ubuhlungu besisu obukhali, isicanucanu, ukuhlanza
• ukuchama kaningi, okubuhlungu, noma okuphuthumayo

Umjovo weCaplacizumab-yhdp ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine esiqandisini, futhi kude nokukhanya. Ungafrizi. Umjovo weCaplacizumab-yhdp ungagcinwa ekamelweni lokushisa izinyanga ezifika kwezimbili kepha kufanele ugcine kwikhathoni lokuqala ukuvikela ekukhanyeni. ICaplacizumab-yhdp akufanele ibuyiselwe esiqandisini ngemuva kokuthi igcinwe ekamelweni lokushisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukopha

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukubheka ukuthi ukwelashwa nge-caplacizumab-yhdp kufanele kuqhutshekwe yini.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla.Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Cablivi^®