I-Pitolisant

-Delile

• Ngaphambi kokuthatha i-pitolisant,
• I-Pitolisant ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Pitolisant isetshenziselwa ukwelapha ukulala ngokweqile emini okubangelwa i-narcolepsy (isimo esibangela ukulala ngokweqile emini) nokwelapha i-cataplexy (iziqephu zobuthakathaka bemisipha eziqala ngokuzumayo futhi zihlale isikhashana) kubantu abadala abane-narcolepsy. UPitolisant usesigabeni semithi ebizwa nge-H₃ abavimba. Isebenza ngokuguqula inani lezinto ezithile zemvelo endaweni yobuchopho elawula ukulala nokuvuka.

IPitolisant iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla ngokushesha nje lapho uvuka ekuseni. Thatha i-pitolisant ngasikhathi sinye nsuku zonke. Ungashintshi isikhathi sosuku osithatha i-pitolisant ngaphandle kokukhuluma nodokotela wakho. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-pitolisant njengoba nje kuqondisiwe.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi we-pitolisant futhi akhuphule kancane umthamo wakho, hhayi ngaphezu kwesisodwa njalo ezinsukwini eziyi-7.

IPitolisant inganciphisa ubuthongo bakho, kepha ngeke ilaphe inkinga yakho yokulala. Kungathatha amasonto ayisishiyagalombili noma ngaphezulu ngaphambi kokuthi uzwe ngokugcwele nge-pitolisant. Qhubeka uthathe i-pitolisant noma ngabe uzizwa uphumule kahle. Ungayeki ukuthatha i-pitolisant ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-pitolisant,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergies kwi-pitolisant, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-pitolisant. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: amiodarone (Nexterone, Pacerone), antihistamines efana ne-diphenhydramine ne-promethazine, carbamazepine (Carbatrol, Epitol, Tegretol), cyclosporine (Gengraf, Neoral, Sandimmune), bupropion (Aplenzin, Forvivo, Wellbutrin Contrave), chlorpromazine, clomipramine (Anafranil), disopyramide (Norpace), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), imipramine (Tofranil), midazolam, mirtazapine (Remeron), moxifloxacin (Aveloetine), Axetine Pexeva), phenytoin (Dilantin, Phenytek), procainamide, rifampin (Rifadin, eRifamate, eRifater, Rimactane), quinidine (eNeudexta), sotalol (Betapace, Sorine, Sotylize), thioridazine, ne-ziprasidone (Geodon). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-pitolisant, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• tshela udokotela wakho uma unesifo sesibindi. Udokotela wakho angakutshela ukuthi ungathathi i-pitolisant.
• utshele udokotela wakho uma uke waba nesikhawu eside se-QT (inkinga yenhliziyo engajwayelekile engadala ukushaya kwenhliziyo okungajwayelekile, ukuquleka, noma ukufa okungazelelwe) noma ukushaya kwenhliziyo okusheshayo, okuhamba kancane, noma okungajwayelekile; futhi uma unamazinga aphansi we-magnesium noma i-potassium egazini lakho; futhi uma unesifo sezinso.
• kufanele wazi ukuthi i-pitolisant inganciphisa ukusebenza kokuvimbela inzalo ngamahomoni (amaphilisi okulawula ukubeletha, amabala, izindandatho, izimila, imijovo, namadivayisi we-intrauterine). Sebenzisa enye indlela yokulawula ukubeletha ngenkathi uthatha i-pitolisant nezinsuku ezingama-21 ngemuva kokuyeka ukuyithatha. Khuluma nodokotela wakho ngezinhlobo zokulawulwa kokuzalwa okuzokusebenzela ngesikhathi nangemva kokwelashwa kwakho nge-pitolisant.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-pitolisant, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Pitolisant ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ubunzima bokulala noma ukulala
• isicanucanu
• ubuhlungu besisu
• ukulahlekelwa isifiso sokudla
• ukutheleleka okuphezulu kokuphefumula
• ubuhlungu bemisipha noma bamalunga
• ukulala ukukhuluma, ukulala ukwethuka, noma ubunzima bokuhamba lapho ulele noma uvuka
• ubuthakathaka bemisipha obuqala ngokuzumayo buhlale isikhashana
• ukuqubuka
• umlomo owomile
• ukukhathazeka
• ukucasuka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukushesha, ukushaya ngamandla, noma ukushaya kwenhliziyo okungajwayelekile
• ukuphefumula kanzima noma ukugwinya
• ukuquleka
• ukubona izinto ezingekho (ukubona izinto noma ukuzwa amazwi angekho)

I-Pitolisant ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Wakix^®