I-Dacarbazine

-Delile

• Ngaphambi kokuthola i-dacarbazine,
• IDacarbazine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

Umjovo we-Dacarbazine kufanele unikezwe esibhedlela noma esikhungweni sezokwelapha ngaphansi kweso likadokotela onolwazi lokunikeza imishanguzo yokwelapha umdlavuza ngamakhemikhali.

IDacarbazine ingadala ukwehla okukhulu kwenani lamaseli egazi emnkantsheni wakho. Lokhu kungadala izimpawu ezithile futhi kungakhuphula ubungozi bokuthi uzoba nokutheleleka okungathi sína noma ukopha. Uma unenani eliphansi lamaseli egazi, udokotela wakho angamisa noma abambezele ukwelashwa kwakho. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokuminyana, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulinyazwa.

IDacarbazine ingadala ukulimala kwesibindi okubi noma okusongela impilo. Ukulimala kwesibindi kungenzeka kaningi kubantu abathola ezinye izidakamizwa zomdlavuza ngamakhemikhali kanye nokwelashwa kwe-dacarbazine. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isicanucanu, ukukhathala ngokweqile, ukopha okungavamile noma ukulimaza, ukungabi namandla, ukulahlekelwa isifiso sokudla, ubuhlungu engxenyeni engakwesokudla esiswini, noma ukuphuzi kwesikhumba noma kwamehlo.

Umjovo we-Dacarbazine ubangele ukukhubazeka kokuzalwa ezilwaneni. Le mithi ayifundwanga kwabesifazane abakhulelwe, kepha kungenzeka ukuthi futhi ingadala ukukhubazeka kokuzalwa ezinganeni ezinonina abathole umjovo we-dacarbazine ngesikhathi sokukhulelwa. Akufanele usebenzise umjovo we-dacarbazine ngenkathi ukhulelwe noma uhlela ukukhulelwa ngaphandle kokuthi udokotela wakho anqume ukuthi lokhu kuyindlela engcono kakhulu yokwelapha isimo sakho.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-dacarbazine.

Khuluma nodokotela wakho ngezingozi zokusebenzisa umjovo we-dacarbazine.

I-Dacarbazine isetshenziselwa ukwelapha i-melanoma (uhlobo lomdlavuza wesikhumba) osudlulele kwezinye izingxenye zomzimba wakho. IDacarbazine isetshenziswa futhi ngokuhlangana neminye imithi yokwelapha iHodgkin's lymphoma (isifo sikaHodgkin's; uhlobo lomdlavuza oluqala ohlotsheni lwamaseli amhlophe egazi avame ukulwa nokutheleleka). IDacarbazine isekilasini lemithi eyaziwa ngokuthi ama-purine analogs. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

Umjovo we-Dacarbazine uza njengempuphu ezohlanganiswa noketshezi oluzofakwa ngaphakathi (emthanjeni) ngaphezu komzuzu owodwa noma lufakwe ngemithambo ngemizuzu engaphezu kwengu-15 kuye kwengu-30 ngudokotela noma unesi esikhungweni sezokwelapha. Lapho i-dacarbazine isetshenziselwa ukwelapha i-melanoma, ingajovwa kanye ngosuku izinsuku eziyishumi zilandelana njalo emavikini amane noma ingajova kanye ngosuku izinsuku ezi-5 zilandelana njalo emavikini ama-3. Lapho i-dacarbazine isetshenziselwa ukwelapha i-Hodgkin's lymphoma ingafakwa kanye ngosuku izinsuku ezi-5 zilandelana njalo emavikini amane noma ingajova kanye ezinsukwini eziyi-15.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-dacarbazine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-dacarbazine, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-dacarbazine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.
• tshela udokotela wakho uma uncelisa.
• hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside futhi ugqoke izingubo zokuzivikela, izibuko zelanga, nesikhumba selanga. IDacarbazine ingenza isikhumba sakho sizwele ekukhanyeni kwelanga.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

IDacarbazine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• isifo sohudo
• izilonda emlonyeni nasemphinjeni
• ukulahleka kwezinwele
• umuzwa wokusha noma ukuncinza ebusweni
• ukuqhuma
• izimpawu ezinjengomkhuhlane

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ububomvu, ubuhlungu, ukuvuvukala, noma ukushisa endaweni lapho umjovo wanikezwa khona
• isifuba
• ukuqubuka kwesikhumba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• umkhuhlane, ubuhlungu bemisipha, nokuzwa okuvamile kobuhlungu nokukhathala

IDacarbazine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-DTIC-Dome^®

• I-Dimethyl Triazeno Imidazol Carboxamide
• Imidazole Carboxamide
• I-DIC
• I-DTIC