Inaliti ye-Cladribine

-Delile

• Ngaphambi kokuthola i-cladribine,
• I-Cladribine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo we-Cladribine kufanele unikezwe esibhedlela noma esikhungweni sezokwelapha ngaphansi kweso likadokotela onolwazi lokunikeza imishanguzo yokwelashwa ngamakhemikhali yomdlavuza.

I-Cladribine ingadala ukwehla okukhulu kwenani lazo zonke izinhlobo zamaseli egazi egazini lakho. Lokhu kungadala izimpawu ezithile futhi kungakhuphula ubungozi bokuthi uzoba nokutheleleka okungathi sína noma ukopha. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulimaza; indle emnyama neyokulinda; igazi elibomvu endle; ukuhlanza kwegazi; noma okokuhlanza okubukeka njengezindawo zekhofi.

I-Cladribine ingadala ukulimala okukhulu kwezinzwa. Ukulimala kwemithambo kungenzeka esikhathini esingaphezu kwenyanga eyodwa ngemuva kokujovwa ngomjovo we-cladribine. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ubuhlungu, ukushiswa, ukuba ndikindiki, noma ukuncinza ezandleni noma ezinyaweni; ubuthakathaka ezandleni noma emilenzeni; noma ukulahlekelwa amandla okuhambisa izingalo noma imilenze.

I-Cladribine ingadala izinkinga ezinkulu zezinso. Tshela udokotela wakho uma uke waba nesifo sezinso noma wake waba naso. Tshela udokotela kanye nosokhemisi wakho uma uthatha ama-antibiotic e-aminoglycoside afana ne-amikacin (Amikin), i-gentamicin (Garamycin), noma i-tobramycin (i-Tobi, i-Nebcin); i-amphotericin B (i-Amphotec, i-Fungizone); i-angiotensin-converting enzyme (ACE) inhibitors efana ne-benazepril (Lotensin), i-captopril (i-Capoten), i-enalapril (i-Vasotec), i-fosinopril (i-Monopril), i-lisinopril (i-Prinivil, i-Zestril), i-moexipril (i-Univasc), i-perindopril) ), i-ramipril (i-Altace), ne-trandolapril (i-Mavik); noma imishanguzo yokulwa nokuvuvukala efana ne-diclofenac (Cataflam, Voltaren), naproxen (Aleve, Naprosyn), ne-sulindac (Clinoril). Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuncipha kokuchama; ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi; ukukhathala okungajwayelekile noma ubuthakathaka.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngaphambi, ngesikhathi, nangemva kokwelashwa ukuze ahlole impendulo yomzimba wakho ku-cladribine.

I-Cladribine isetshenziselwa ukwelapha i-hairy cell leukemia (umdlavuza wohlobo oluthile lweseli emhlophe yegazi). I-Cladribine isekilasini lemithi eyaziwa ngokuthi ama-purine analogs. Isebenza ngokumisa noma ukunciphisa ukukhula kwamangqamuzana omdlavuza.

Umjovo we-Cladribine uza njengesisombululo (uketshezi) esizofakwa ngaphakathi (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Imvamisa inikezwa kancane ngaphezulu kwezinsuku eziyi-7 njengomjovo oqhubekayo wokufaka emthanjeni.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-cladribine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-cladribine, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-cladribine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nokunye okulandelayo: ama-immunosuppressants anjenge-azathioprine (Imuran), i-cyclosporine (i-Neoral, i-Sandimmune), i-methotrexate (i-Rheumatrex), i-sirolimus (i-Rapamune), ne-tacrolimus (i-Prograf). Udokotela wakho uzodinga ukukuqapha ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-cladribine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Akufanele ukhulelwe ngenkathi uthola i-cladribine. Uma ukhulelwa ngenkathi uthola i-cladribine, shayela udokotela wakho. I-Cladribine ingalimaza umbungu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Cladribine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ubuhlungu besisu
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• ukuqubuka kwesikhumba
• ikhanda
• ukujuluka okweqile
• ubuhlungu, ububomvu, ukuvuvukala, noma izilonda endaweni lapho umjovo wafakwa khona

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• isikhumba esiphaphathekile
• ukukhathala ngokweqile
• ukuphelelwa umoya
• isiyezi
• ukushaya kwenhliziyo okusheshayo

I-Cladribine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuncipha kokuchama
• ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukopha okungajwayelekile noma ukulinyazwa
• ezimnyama nezilindayo noma ezinezihlalo ezinegazi
• ukuhlanza okunegazi noma okokuhlanza okubukeka njengezizathu zekhofi
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukuncinza ezandleni noma ezinyaweni
• ubuthakathaka ezandleni noma emilenzeni.
• ukulahlekelwa amandla okuhambisa izingalo noma imilenze.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• ILeustatin^®

• 2-CdA
• 2-Chloro-2’-deoxyadenosine
• CdA
• I-chlorodeoxyadenosine