Umlobi: Marcus Baldwin
Usuku Lokudalwa: 20 Ujuni 2021
Ukuvuselela Usuku: 18 Unovemba 2024
Anonim
Inaliti ye-Octreotide - Umuthi
Inaliti ye-Octreotide - Umuthi

-Delile

Umjovo wokukhishwa ngokushesha kwe-Octreotide usetshenziselwa ukunciphisa inani le-hormone yokukhula (into yemvelo) ekhiqizwa abantu abane-acromegaly (isimo lapho umzimba ukhiqiza khona i-hormone yokukhula eningi kakhulu, kubangele ukukhuliswa kwezandla, izinyawo, nobuso; ubuhlungu obuhlangene ; nezinye izimpawu) abangenakulashwa ngokuhlinzwa, ngemisebe, noma ngomunye umuthi.Umjovo wokukhishwa ngokushesha kwe-Octreotide nawo usetshenziselwa ukulawula isifo sohudo nokugeleza okubangelwa amathumba e-carcinoid (izicubu ezikhula kancane ezikhipha izinto zemvelo ezingadala izimpawu) kanye ne-vasoactive amathumbu we-peptide wokufihla ama-adenomas (i-VIP-omas; izimila ezakha amanyikwe bese ziyadedelwa izinto zemvelo ezingadala izimpawu). Umjovo we-Octreotide osebenza isikhathi eside usetshenziselwa ukulawula i-acromegaly, izicubu ze-carcinoid, nama-VIP-omas kubantu abaphathwe ngempumelelo ngomjovo we-octreotide kodwa bakhetha ukuthola imijovo kaningi. Umjovo we-Octreotide usesigabeni semithi ebizwa nge-octapeptides. Isebenza ngokunciphisa inani lezinto ezithile zemvelo ezikhiqizwa ngumzimba.


I-Octreotide iza njengesisombululo sokukhishwa ngokushesha (uketshezi) somjovo ozofakwa ngaphansi kwesikhumba (noma ngaphansi kwesikhumba) noma ngemithambo (emthanjeni) I-Octreotide nayo iza njengomjovo osebenza isikhathi eside ozofakwa emisipha yezinqa ngudokotela noma umhlengikazi. Umjovo wokukhishwa ngokushesha kwe-Octreotide uvame ukujova ama-2 izikhathi ezi-4 ngosuku. Umjovo we-Octreotide osebenza isikhathi eside ujovwa kanye njalo emavikini amane. Jova i-octreotide umjovo wokukhishwa ngokushesha ngezikhathi ezifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Jova umjovo we-octreotide njengoba nje uqondisiwe. Ungayifaki ngaphezulu noma ngaphansi kwayo noma uyijoje kaningi kunokuyalelwa ngudokotela wakho.

Uma ungakalashwa ngomjovo we-octreotide, uzoqala ukwelashwa kwakho ngomjovo we-octreotide okhishwa ngokushesha. Uzokwelashwa ngomjovo okhishwa ngokushesha wamaviki ama-2, futhi udokotela wakho angakhuphula kancane umthamo wakho ngaleso sikhathi. Uma umuthi usebenza kuwe futhi ungabangeli imiphumela emibi kakhulu, udokotela wakho angakunika umjovo osebenza isikhathi eside ngemuva kwamasonto amabili. Ukuze ulawule isimo sakho, kungadingeka ukuthi uqhubeke nokuthola umjovo okhishwa ngokushesha amasonto ama-2 noma ngaphezulu ngemuva kokuthola umthamo wakho wokuqala womjovo osebenza isikhathi eside. Udokotela wakho angakhuphula noma anciphise umthamo wakho womjovo osebenza isikhathi eside ezinyangeni ezi-2 noma ezi-3 ngemuva kokuwuthola okokuqala.


Uma welashelwa isimila se-carcinoid noma i-VIP-oma, ungahle ube nezimpawu zokuwohloka kwezimpawu zakho ngezikhathi ezithile ngesikhathi sokwelashwa kwakho. Uma lokhu kwenzeka, udokotela wakho angakutshela ukuthi usebenzise umjovo wokukhishwa ngokushesha izinsuku ezimbalwa kuze kube yilapho izimpawu zakho zilawulwa.

Uma une-acromegaly futhi welashwa nge-radiation therapy, udokotela wakho mhlawumbe uzokutshela ukuthi ungasebenzisi umjovo wokukhishwa ngokushesha kwe-octreotide amasonto ama-4 minyaka yonke noma ungatholi umjovo we-octreotide osebenza isikhathi eside amasonto ayi-8 minyaka yonke. Lokhu kuzovumela udokotela wakho ukuthi abone ukuthi ukwelashwa ngemisebe kusithinte kanjani isimo sakho futhi anqume ukuthi kusamele uphathwe nge-octreotide.

Umjovo wokukhishwa ngokushesha kwe-Octreotide ufika ngezimbiza, ama-ampule, namapeni wokulinganisa aqukethe ama-cartridges emithi. Qiniseka ukuthi uyazi ukuthi uluphi uhlobo lwesitsha i-octreotide yakho engenayo nokuthi iziphi ezinye izinto, njengezinaliti, imijovo, noma amapeni, ozodinga ukujova umuthi wakho.

Uma usebenzisa umjovo okhishwa ngokushesha ovela esitsheni, ipeni le-ampule noma i-dosing, ungakwazi ukujova umuthi ngokwakho ekhaya noma ube nomngane noma isihlobo esenza imijovo. Cela udokotela wakho akukhombise noma umuntu ozobe ejova ukuthi angajova kanjani umuthi. Futhi khuluma nodokotela wakho mayelana nokuthi kufanele uwufake kuphi umjovo emzimbeni wakho nokuthi kufanele uzungeze kanjani izindawo ezinomjovo ukuze ungafaki endaweni efanayo kaningi. Ngaphambi kokujova umuthi wakho, bheka njalo uketshezi. futhi ungayisebenzisi uma kunamafu noma kuqukethe izinhlayiya. Bheka ukuthi usuku lokuphelelwa yisikhathi aludlulanga yini, nokuthi isisombululo somjovo siqukethe inani elifanele loketshezi, nokuthi uketshezi lucacile futhi alunambala. Ungasebenzisi ipeni le-vial, ampule, noma i-dosing uma liphelelwe yisikhathi, uma lingaqukethe inani elifanele loketshezi, noma uma uketshezi lunamafu noma lunemibala.


Funda ngokucophelela imiyalelo yomkhiqizi yokusetshenziswa eza nomuthi. Le miyalo ichaza ukuthi ungawujova kanjani umthamo womjovo we-octreotide. Qiniseka ukuthi ubuza usokhemisi noma udokotela wakho uma unemibuzo mayelana nokuthi ungawujova kanjani lo muthi.

Lahla izibaya zomthamo ezisetshenzisiwe, izitsha, ama-ampule, noma imijovo esitsheni esingamelana nokubhoboza. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Umjovo we-Octreotide ungalawula izimpawu zakho, kepha ngeke uselaphe isimo sakho. Qhubeka nokusebenzisa umjovo we-octreotide noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa umjovo we-octreotide ngaphandle kokukhuluma nodokotela wakho. Uma uyeka ukusebenzisa umjovo we-octreotide, izimpawu zakho zingabuya.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-octreotide,

  • Tshela udokotela wakho kanye nosokhemisi uma une-aleji kumjovo we-octreotide, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-octreotide. Buza usokhemisi wakho ukuthola uhlu lwezithako. Uma uzosebenzisa umjovo osebenza isikhathi eside, phinda utshele udokotela wakho uma unegciwane ku-latex.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-beta blocker anjenge-atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), nepropranolol (Inderal); i-bromocriptine (i-Cycloset, i-Parlodel); ama-calcium channel blocker afana ne-amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), nifedipine (Adalat, Procardia), nisoldipine (Sular), kanye ne-verapamil (Calan, Isoptin, Verelan); i-cyclosporine (Gengraf, Neoral, Sandimmune); i-insulin nemithi yomlomo yesifo sikashukela; i-quinidine; kanye ne-terfenadine (Seldane) (ayitholakali e-U.S.). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
  • Tshela udokotela wakho ukuthi wondliwa yini ngokudla okuphelele kwe-parenteral (TPN; ukondla ngokunikeza uketshezi oluqukethe izakhi ngqo emthanjeni) futhi uma ngabe uke waba nesifo sikashukela noma senhliziyo, isibindi noma isifo sezinso.
  • tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Ungakwazi ukukhulelwa ngesikhathi ukwelashwa kwakho nge-octreotide noma ngabe ubungakwazi ukukhulelwa ngaphambi kokwelapha kwakho ngoba une-acromegaly. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma ukhulelwa ngenkathi uthola umjovo we-octreotide, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma ukhohlwa ukujova umjovo womjovo okhishwa ngokushesha, jovelela umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi sedosi yakho elandelayo, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Musa ukujova umthamo ophindwe kabili ukwenzela okulahlekile.

Uma uphuthelwa i-aphoyintimenti yokuthola umthamo womjovo osebenza isikhathi eside, shayela udokotela wakho ukuthi ahlele kabusha ukuqokwa.

Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophakeme nophansi nokuthi yini okufanele uyenze uma unalezi zimpawu.

Umjovo we-Octreotide ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • isifo sohudo
  • ukuqunjelwa
  • izitulo eziphaphathekile, ezinkulu, ezinuka kabi
  • ukuzwa njalo isidingo sokukhipha amathumbu
  • igesi
  • ubuhlungu besisu
  • isicanucanu
  • isilungulela
  • ikhanda
  • isiyezi
  • ukukhathala
  • emuva, imisipha, noma ubuhlungu obuhlangene
  • ekhaleni
  • ukulahleka kwezinwele
  • ubuhlungu endaweni lapho umjovo wafakwa khona
  • umbono uyashintsha

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

  • ubuhlungu engxenyeni engenhla kwesokudla yesisu, maphakathi nesisu, emuva, noma ehlombe
  • ukuphuzi kwesikhumba noma kwamehlo
  • ukushaya kwenhliziyo okuphuzile noma okungajwayelekile
  • ukuvilapha
  • ukuzwela emakhazeni
  • isikhumba esiphaphathekile nesomile
  • izinzipho ezinemilenze nezinwele
  • ubuso obukhukhumele
  • izwi elihoshozelayo
  • ukudana
  • izikhathi ezinzima zokuya esikhathini
  • ukuvuvukala phansi kwentamo
  • ukuqina emphinjeni
  • ubunzima bokuphefumula nokugwinya
  • ukuqubuka
  • ukulunywa

Umjovo we-Octreotide ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma ugcina umjovo osebenza isikhathi eside ekhaya lakho kuze kufike isikhathi sokuthi ujojowe ngudokotela noma unesi wakho, kufanele uwugcine kumabhokisi okuqala esiqandisini futhi uwuvikele ekukhanyeni. Uma uzogcina isisombululo sokukhishwa ngokushesha komjovo kuma-ampulets, izitsha, noma izibaya zokulinganisa, kufanele usigcine kubhokisi lokuqala lokuqala esiqandisini ukulivikela ekukhanyeni; ungafrizi. Ungagcina imishanguzo yemithamo eminingi ekhishwa ngokushesha ngemuva kokuyisebenzisa okokuqala ekamelweni lokushisa kuze kube yizinsuku eziyi-14. Ungagcina ipeni lomthamo okhishwa ngokushesha ekamelweni lokushisa ngemuva kokusetshenziswa kokuqala kuze kube yizinsuku ezingama-28 ngesikhwama sepeni ngaso sonke isikhathi. Ungagcina imishanguzo yedosi elilodwa lomjovo okhishwa ngokushesha kanye nama-ampuler ekamelweni lokushisa kuze kube yizinsuku eziyi-14, kepha ulahle noma yisiphi isixazululo esingasetshenzisiwe kuma-ampule noma izigaxa zethamo elilodwa ngemuva kokusetshenziswa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

  • ukushaya kwenhliziyo okuphuzile noma okungajwayelekile
  • isiyezi
  • ukuquleka
  • ukuqhuma
  • isifo sohudo
  • ubuthakathaka
  • ukuncipha komzimba

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho kumjovo we-octreotide.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

  • I-Bynfezia®
  • ISandostatin®
  • ISandostatin® ILAR Depot
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