ILatuda (lurasidone): yenzelwe ini, ungayithatha kanjani nemiphumela engemihle

-Delile

• Yenzelwe ini
• Ungathatha kanjani
• Imiphumela emibi engaba khona
• Ubani okungafanele athathe

ILurasidone, eyaziwa ngegama lokuhweba iLatuda, iwumuthi osezigabeni zama-antipsychotic, osetshenziselwa ukwelapha izimpawu zeschizophrenia kanye nokudangala okubangelwa ukuphazamiseka kwe-bipolar.

Lo muthi usanda kuvunywa yi-Anvisa ukudayiswa emakhemisi eBrazil, ngamaphilisi angama-20mg, 40mg kanye nama-80mg, ngamaphakethe amaphilisi ayi-7, 14, 30 noma angama-60, futhi angatholakala noma a-odolwe emakhemisi amakhulu. Njengoba kuyi-antipsychotic, iLurasidone iyingxenye yesigaba semithi elawulwayo futhi ithengiswa kuphela ngomuthi okhethekile kumakhophi amabili.

Yenzelwe ini

I-Lurasidone isetshenziselwa ukwelapha:

• ISchizophrenia, kubantu abadala nentsha eneminyaka engu-13 kuya kwengu-18;
• Ukudangala okuhambisana nesifo se-bipolar, kubantu abadala, njengomuthi owodwa noma ngokuhlangana nabanye, njenge-lithium noma i-valproate.

Lo muthi uyi-antipsychotic, esebenza njenge-ejenti ekhethiwe yokuvimbela imiphumela ye-dopamine ne-monoamine, eyi-neurotransmitters yobuchopho, ebalulekile ekuthuthukiseni izimpawu.

Kodwa-ke, isebenza ngokuthuthuka okuthile maqondana nama-antipsychotic amadala, njengokushintshwa okuncane kokugaya umzimba, okuba nomthelela omncane ekuzuzeni isisindo nasekushintsheni kweprofayili yomzimba noshukela womzimba.

Ungathatha kanjani

Amaphilisi e-Lurasidone kufanele athathwe ngomlomo, kanye ngosuku, kanye nokudla, futhi kunconywa ukuthi athathwe ngasikhathi sinye usuku ngalunye. Ngaphezu kwalokho, amaphilisi kufanele agwinywe ephelele, ukugwema ukunambitheka kwawo okumunyu.

Imiphumela emibi engaba khona

Eminye yemiphumela emibi kakhulu yeLurasidone ukozela, ukungahlaliseki, isiyezi, ukunyakaza okungazibandakanyi, ukuqwasha, ukuphazamiseka, ukukhathazeka noma ukuzuza kwesisindo.

Eminye imiphumela engaba khona ukuquleka, ukuncipha kwesifiso sokudla, ukucobeka, ukungaboni kahle, i-tachycardia, ushintsho kumfutho wegazi, isiyezi noma izinguquko ekubalweni kwegazi, isibonelo.

Ubani okungafanele athathe

I-Lurasidone iyaphikiswa lapho kukhona:

• Ukuzwela okukhulu kwesithako esisebenzayo noma kunoma ikuphi kokuxhunywayo kuthebulethi;
• Ukusetshenziswa kwezidakamizwa eziqinile ze-CYP3A4, njengeBoceprevir, Clarithromycin, Voriconazole, Indinavir, Itraconazole noma iKetoconazole, isibonelo;
• Ukusetshenziswa kwezidakamizwa eziqinisa i-CYP3A4, njengeCarbamazepine, iPhenobarbital, Phenytoin, Rifampicin noma iSt John's wort, isibonelo.

Ngenxa yokusebenzisana nomphumela wale mithi, uhlu lwemithi esetshenzisiwe kumele njalo lwaziswe kudokotela ohambisanayo.

I-Lurasidone kufanele isetshenziswe ngokuqapha ngabantu abanesifo sezinso noma esilinganiselwe kuya kwesifo esibi sesifo, isifo sikaParkinson, ukuphazamiseka kokuhamba, isifo senhliziyo nemithambo yegazi noma ezinye izifo zemizwa. Ngaphezu kwalokho, lo muthi awuzange uhlolwe ezigulini esezikhulile ezine-dementia noma ezinganeni, ngakho-ke ukusetshenziswa kufanele kugwenywe kulezi zimo.