I-Immunoelectrophoresis - igazi

I-Serum immunoelectrophoresis ukuhlolwa kwelebhu okulinganisa amaprotheni abizwa ngama-immunoglobulin egazini. Ama-immunoglobulin amaphrotheni asebenza njengama-antibodies, alwa nokutheleleka. Kunezinhlobo eziningi zama-immunoglobulin alwa nezinhlobo ezahlukene zezifo. Amanye ama-immunoglobulins angajwayelekile futhi angabangelwa umdlavuza.

Ama-immunoglobulin nawo angalinganiswa emchameni.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile kwalokhu kuhlolwa.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

Lokhu kuhlolwa kuvame ukusetshenziselwa ukuhlola amazinga ama-antibodies lapho umdlavuza othile nezinye izifo zikhona noma kusolwa.

Umphumela ojwayelekile (ongemuhle) usho ukuthi isampula legazi linezinhlobo ezijwayelekile zama-immunoglobulin. Izinga le-immunoglobulin eyodwa lalingephakeme kunanoma iyiphi enye.

Imiphumela engajwayelekile ingabangelwa:

• I-myeloma eminingi (uhlobo lomdlavuza wegazi)
• I-lymphocytic leukemia noma i-Waldenström macroglobulinemia (izinhlobo zomdlavuza wamangqamuzana amhlophe egazi)
• I-Amyloidosis (inqwaba yamaprotheni angajwayelekile ezicutshini nasezithweni)
• I-Lymphoma (umdlavuza wezicubu ze-lymph)
• Ukuhluleka kwezinso
• Ukutheleleka

Abanye abantu banama-immunoglobulin amaningi, kodwa abanawo umdlavuza. Lokhu kubizwa ngokuthi yi-monoclonal gammopathy yokubaluleka okungaziwa, noma i-MGUS.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

IEP - i-serum; Immunoglobulin electrophoresis - igazi; I-Gamma globulin electrophoresis; I-serum immunoglobulin electrophoresis; I-Amyloidosis - i-electrophoresis serum; I-myeloma eminingi - i-serum electrophoresis; I-Waldenström - i-serum electrophoresis

• Ukuhlolwa kwegazi

U-Aoyagi K, Ashihara Y, Kasahara Y. Ama-Immunoassays kanye ne-immunochemistry. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 44.

IKricka LJ, iPark JY. Amasu we-immunochemical. Ku: Rifai N, ed. I-Tietz Textbook ye-Clinical Chemistry kanye ne-Molecular Diagnostics. Umhlaka 6. ISt Louis, MO: Elsevier; 2018: isahluko 23.