I-immunoelectrophoresis - umchamo

I-urine immunoelectrophoresis ukuhlolwa kwelebhu okulinganisa ama-immunoglobulin kusampula yomchamo.

Ama-immunoglobulin amaphrotheni asebenza njengama-antibodies, alwa nokutheleleka. Kunezinhlobo ezahlukahlukene zala maprotheni alwa nezinhlobo ezahlukene zezifo. Amanye ama-immunoglobulins angajwayelekile futhi angabangelwa umdlavuza.

Ama-immunoglobulin nawo angalinganiswa egazini.

Isampula yomchamo wokubamba ehlanzekile iyadingeka.Indlela yokubamba ehlanzekile isetshenziselwa ukuvimbela amagciwane avela endondeni noma esithweni sangasese ekungeneni kusampula yomchamo. Ukuqoqa umchamo wakho, umhlinzeki wezokunakekelwa kwempilo angakunika ikhithi ekhethekile yokubamba ehlanzekile equkethe isisombululo sokuhlanza kanye nokusula okuyinyumba. Landela imiyalo ngqo.

Ngemuva kokunikeza isampula yomchamo, ithunyelwa elabhorethri. Lapho, isazi selabhorethri sizobeka isampula lomchamo ephepheni elikhethekile bese sisebenzisa amandla kagesi. Amaprotheni ahlukahlukene anyakaza futhi akha amabhendi abonakalayo, aveza inani elijwayelekile leprotheyini ngalinye.

Umhlinzeki wakho angakucela ukuthi uqoqe umchamo wokuqala wasekuseni, okugxilwe kakhulu.

Uma uthatha iqoqo kusana, ungadinga izikhwama zokuqoqa ezengeziwe.

Isivivinyo sihilela ukuchama okujwayelekile kuphela, futhi akukho ukungaphatheki kahle.

Lokhu kuhlolwa kusetshenziselwa ukukala inani lama-immunoglobulin ahlukahlukene emchameni. Ngokuvamile, kwenziwa ngemuva kokutholakala kwenani elikhulu lamaprotheni emchameni.

Imvamisa awekho amaprotheni, noma inani elincane kuphela lamaprotheni emchameni. Lapho kunamaprotheni emchameni, imvamisa iqukethe i-albhamuin ikakhulukazi.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

I-immunoglobulin emchameni ingavela ku:

• Ukwakhiwa okungajwayelekile kwamaprotheni kwizicubu nezitho (i-amyloidosis)
• Umdlavuza wegazi
• Umdlavuza wegazi obizwa nge-multiple myeloma
• Ukuphazamiseka kwezinso ezinjenge-IgA nephropathy noma i-IgM nephropathy

Abanye abantu banama-immunoglobulin amaningi, kodwa abanawo umdlavuza. Lokhu kubizwa ngokuthi yi-monoclonal gammopathy yokubaluleka okungaziwa, noma i-MGUS.

Immunoglobulin electrophoresis - umchamo; I-Gamma globulin electrophoresis - umchamo; Umchamo we-immunoglobulin electrophoresis; IEP - umchamo

• Umgudu womchamo wabesifazane
• Umgudu womchamo wabesilisa

IChernecky CC, iBerger BJ. Amaprotheni electrophoresis - umchamo. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 920-922.

UGertz MA. I-Amyloidosis. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 179.

UMcPherson RA. Amaprotheni athile. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 19.

URajkumar SV, iDispenzieri A. I-myeloma eminingi kanye nokuphazamiseka okuhlobene. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, abahleli. I-Abeloff’s Clinical Oncology. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2020: isahluko 101.