Ukujova kweCetuximab

-Delile

• Ngaphambi kokuthola ukwelashwa nge-cetuximab,
• I-Cetuximab ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

I-Cetuximab ingadala ukusabela okunzima noma okusongela impilo ngenkathi uthola umuthi. Lokhu kusabela kuvame kakhulu ngomthamo wokuqala we-cetuximab kepha kungenzeka nganoma yisiphi isikhathi ngenkathi welashwa. Udokotela wakho uzokubuka ngokucophelela ngenkathi uthola umthamo ngamunye we-cetuximab futhi okungenani ihora elilodwa ngemuva kwalokho. Tshela udokotela wakho uma uxabana nenyama ebomvu, noma uma wake walunywa umkhaza. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi sokumnika noma ngemuva kokumnika ukutshela udokotela wakho ngokushesha: ukuphefumula kanzima ngokuzumayo, ukuphefumula okuncane, ukuphefumula noma ukuphefumula okunomsindo, ukuvuvukala kwamehlo, ubuso, umlomo, izindebe noma umphimbo, ukushuba, isifuba, ukuquleka, isiyezi, isicanucanu, umkhuhlane, ukubanda, noma ubuhlungu besifuba noma ingcindezi. Uma uhlangabezana nenye yalezi zimpawu udokotela wakho anganciphisa noma ayeke ukumnika kwakho futhi aphathe izimpawu zempendulo. Ungahle ungakwazi ukwelashwa nge-cetuximab ngokuzayo.

Abantu abanomdlavuza wekhanda nentamo abaphathwa ngemishanguzo ye-radiation kanye ne-cetuximab bangaba nengozi eyengeziwe yokuboshwa kwe-cardiopulmonary (isimo lapho inhliziyo iyeka ukushaya nokuphefumula kuyeka) kanye nokufa okungazelelwe ngesikhathi noma ngemuva kokwelapha kwabo. Tshela udokotela wakho uma uke waba nesifo semithambo yegazi noma (wake waba naso lapho kwenzeka ukuthi imithambo yegazi yenhliziyo incishiswe noma ivaleke ngamafutha noma i-cholesterol deposits); ukwehluleka kwenhliziyo (isimo lapho inhliziyo ingakwazi ukupompa igazi elanele kwezinye izingxenye zomzimba); ukushaya kwenhliziyo okungajwayelekile; esinye isifo senhliziyo; noma ngaphansi kwezinga elijwayelekile le-magnesium, i-potassium, noma i-calcium egazini lakho.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngesikhathi nangemva kokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-cetuximab.

Khuluma nodokotela wakho ngezingozi zokusebenzisa i-cetuximab.

I-Cetuximab isetshenziselwa ukwelashwa ngemisebe noma ngaphandle kwemisebe ukwelapha uhlobo oluthile lomdlavuza wekhanda nentamo osabalele ezicutshini eziseduze noma kwezinye izingxenye zomzimba. Ingasetshenziswa futhi neminye imithi yokwelapha uhlobo oluthile lomdlavuza wekhanda nentamo osabalele kwezinye izingxenye zomzimba noma oqhubeka ubuya ngemuva kokwelashwa. I-Cetuximab nayo isetshenziswa yodwa noma ihlanganiswe neminye imithi yokwelapha uhlobo oluthile lomdlavuza wekoloni (amathumbu amakhulu) noma i-rectum esabalele kwezinye izingxenye zomzimba. I-Cetuximab isekilasini lemithi ebizwa ngama-antibody monoclonal. Isebenza ngokunciphisa noma ngokumisa ukukhula kwamangqamuzana omdlavuza.

ICetuximab iza njengesisombululo (uketshezi) ukuze ifakwe (ijojowe kancane) emthanjeni. ICetuximab inikezwa ngudokotela noma umhlengikazi ehhovisi lezokwelapha noma esikhungweni sokumnika. Isikhathi sokuqala lapho uthola khona i-cetuximab, izofakwa isikhathi esingamahora ama-2, khona-ke amanani alandelayo azofakwa ngaphezu kwehora elilodwa. I-Cetuximab ivame ukunikezwa kanye ngesonto inqobo nje uma udokotela wakho encoma ukuthi uthole ukwelashwa.

Udokotela wakho angadinga ukwehlisa ukumnika kwakho, ukunciphisa umthamo wakho, ukubambezela noma ukumisa ukwelashwa kwakho, noma ukukuphatha ngeminye imithi uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-cetuximab.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola ukwelashwa nge-cetuximab,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-cetuximab, noma eminye imithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.
• utshele udokotela wakho uma uke waba nesifo senhliziyo noma wake waba naso.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Kuzofanele wenze ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa. Akufanele ukhulelwe ngenkathi welashwa nge-cetuximab futhi okungenani izinyanga ezimbili ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. Uma ukhulelwa ngenkathi uthola i-cetuximab, shayela udokotela wakho.
• tshela udokotela wakho uma uncelisa. Udokotela wakho angakutshela ukuthi ungancelisi ngesikhathi sokwelashwa kwakho nezinyanga ezimbili ngemuva komthamo wakho wokugcina.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala kwabesifazane. Khuluma nodokotela wakho ngezingozi zokuthola i-cetuximab.
• hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside futhi ugqoke izingubo zokuzivikela, isigqoko, izibuko zelanga, nesikrini selanga ngesikhathi sokwelashwa kwakho nge-cetuximab kanye nezinyanga ezimbili ngemuva kokwelashwa kwakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa isikhathi sokuthola i-cetuximab, shayela udokotela wakho ngokushesha.

I-Cetuximab ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqubuka okufana nezinduna
• isikhumba esomile noma esiqhekezayo
• ukulunywa
• ukuvuvukala, ubuhlungu, noma izinguquko kuzinzipho noma ezinzwaneni
• (amehlo) abomvu, amanzi, noma alumayo
• ijwabu leso (elibomvu noma elivuvukile)
• ubuhlungu noma umuzwa ovuthayo esweni (s)
• ukuzwela kwamehlo ekukhanyeni
• ukulahleka kwezinwele
• ukukhula kwezinwele ekhanda, ebusweni, ezinkophe, noma esifubeni
• izindebe eziqhekekile
• ikhanda
• ukukhathala
• ubuthakathaka
• ukudideka
• ukuba ndikindiki, ukushosholoza, ubuhlungu, noma ukushiswa izingalo noma imilenze
• umlomo owomile
• izilonda ezindebeni, emlonyeni, noma emphinjeni
• Umphimbo obuhlungu
• isicanucanu
• ukuhlanza
• shintsha emandleni okunambitha ukudla
• ukulahlekelwa isifiso sokudla
• ukuncipha komzimba
• ukuqunjelwa
• isifo sohudo
• isilungulela
• ubuhlungu obuhlangene
• ubuhlungu bamathambo
• ubuhlungu, ububomvu, noma ukuvuvukala endaweni lapho kwajova khona umuthi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukulahleka kombono
• ukushwabana, ukuxebuka, noma ukuchitha isikhumba
• isikhumba esibomvu, esivuvukile, noma esinegciwane
• ukukhwehlela okusha noma okuba kubi, ukuphefumula okuncane, noma ubuhlungu besifuba

I-Cetuximab ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Buza udokotela wakho uma unemibuzo mayelana nokwelashwa kwakho nge-cetuximab.

Kwezinye izimo, udokotela wakho uzokuyalela ukuhlolwa kwelebhu ngaphambi kokuba uqale ukwelashwa kwakho ukuze ubone ukuthi umdlavuza wakho ungelashwa nge-cetuximab.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Erbitux^®